Decreased incubation of fentanyl seeking in the absence of proximal drug-paired stimuli.

Treating substance use disorders is difficult as individuals often resume substance use during abstinence. One potential factor contributing to the recurrence of substance use is incubation of drug craving. Specifically, individuals report higher levels of craving when presented with drug-paired stimuli across abstinence, although this effect is largely absent in opioid-dependent individuals.

Increasing provider awareness of Lp(a) testing for patients at risk for cardiovascular disease: A comparative study.

Background: Lipoprotein(a) [Lp(a)] is a low-density lipoprotein variant with atherogenic, thrombogenic, and pro-inflammatory properties that may have numerous pathologic effects, including dyslipidemia. Screening for Lp(a) is clinically significant, due to its causal role in atherosclerotic cardiovascular disease (ASCVD). Among clinicians, however, there remains a general lack of both clinical awareness of Lp(a) and adequate tools to track Lp(a) testing in patients.

Challenges and Research Opportunities for Integrating Quantitative Electroencephalography Into Sports Concussion Rehabilitation.

Although concussion management and return to play/learn decision making focuses on reducing symptoms, there is growing interest in objective physiological approaches to treatment. Clinical and technological advancements have aided concussion management; however, the scientific study of the neurophysiology of concussion has not translated into its standard of care. This expert commentary is motivated by novel clinical applications of electroencephalographic-based neurofeedback approaches (eg, quantitative electroencephalography [QEEG]) for treating traumatic brain injury and emerging research interest in its translation for treating concussion.

Countermovement Jumps and Acute to Chronic Workload Ratios in Low, Moderate, and High Jump Load Groups Throughout a Division I Volleyball Season.

Sanders, GJ, Skodinski, S, Cabarkapa, DV, Howard, M, Cabarkapa, D, Kollock, RO, and Peacock, CA. Countermovement jumps and acute to chronic workload ratios in low, moderate, and high jump load groups throughout a Division I volleyball season. J Strength Cond Res XX(X): 000-000, 2024-The purpose of the study was to evaluate the effects of low, moderate, and high jump loads on the acute to chronic workload ratio (ACWR) and neuromuscular fatigue throughout a Division I volleyball season.

Progerin can induce DNA damage in the absence of global changes in replication or cell proliferation.

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by features of accelerated aging, and individuals with HGPS seldom live beyond their mid-teens. The syndrome is commonly caused by a point mutation in the LMNA gene which codes for lamin A and its splice variant lamin C, components of the nuclear lamina. The mutation causing HGPS leads to production of a truncated, farnesylated form of lamin A referred to as "progerin.

KF4 Anti-Chymotrypsin-like Elastase 1 Antibody and Purified Alpha-1 Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine Alpha-1 Antitrypsin Deficiency.

Alpha-1 antitrypsin (AAT) deficiency is the most common genetic cause of emphysema. Chymotrypsin-like Elastase 1 (CELA1) is a serine protease neutralized by AAT and is important in emphysema progression. Cela1-deficiency is protective in a murine models of AAT-deficient emphysema.

Post-concussion changes in the N200 and P300 ERPs are associated with cognitive symptoms and performance.

Purpose: To examine how post-concussion changes to the N200 and P300 event-related potentials (ERPs) are associated with cognitive symptoms and neurocognitive performance.

Methods: High-density electroencephalography (EEG) was recorded during a Go/No-Go task from 16 young adults within one month after their concussion and 16 matched controls. Participants were also administered the Cognitive-Linguistic Quick Test (CLQT) and self-reported concussion-like symptoms.

Sulfites and sulfates formed by weathering of early martian carbonates in a sulfur dioxide-bearing atmosphere.

Despite ample evidence that extensive water-rock interactions occurred under a CO-dominated atmosphere on early Mars, carbonate minerals are relatively rare at the surface. One possibility to explain this scarcity is that carbonates were initially abundant, but were later destroyed when atmospheric conditions changed, particularly as a result of volcanism releasing large volumes of sulfur dioxide SO into the atmosphere. However, despite some early theoretical and experimental results, no study has investigated the stability of the most common carbonates (Ca, Mg and Fe) in the presence of abundant SO gas.

Designing high-performance asymmetric and hybrid energy devices via merging supercapacitive/pseudopcapacitive and Li-ion battery type electrodes.

We report a strategic development of asymmetric (supercapacitive-pseudocapacitive) and hybrid (supercapacitive/pseudocapacitive-battery) energy device architectures as generation-II electrochemical energy systems. We derived performance-potential estimation regarding the specific power, specific energy, and fast charge-discharge cyclic capability. Among the conceived group, pseudocapacitor-battery hybrid device is constructed with a high-rate intrinsic asymmetric pseudocapacitive (α - MnO/rGO) and a high-capacity Li-ion intercalation battery type (po-nSi/rGO) electrodes.

Aging and the visual perception of rigid and nonrigid motion.

Nonrigid forms of motion are commonplace in everyday life. Given previously documented age-related deteriorations in various tasks involving motion (discriminating speed, identifying motion direction, etc.), an experiment was conducted to evaluate the potential effect of age upon the visual ability to detect rigid and nonrigid object motion.

Calcium alginate-biochar composite immobilized A. ferrooxidans effectively removes sulfate and ferric iron from acid mine drainage.

Bioremediation has been applied in the treatment of acid mine drainage (AMD), but high levels of sulfate (SO) and ferric iron (Fe) in AMD often affect microbial activity. A novel biochar-microorganism composite (I-CMR600) was developed by alginate gel-embedding method to improve the tolerance of microorganisms and the removal effects of SO and Fe in AMD, and its removal mechanism and biological behavior were explored in this study. The removal performance of I-CMR600 under different influencing factors was studied by batch adsorption experiments.

MOSQUITO SPECIES DISTRIBUTION IN TIRES IN RURAL AND URBAN LANDSCAPES ACROSS NORTHERN KENTUCKY.

Discarded vehicle tires can be found in habitats spanning a human land-use gradient from rural to urban and create an ideal artificial container habitat for mosquito larval development. The purpose of this study was to examine mosquito species composition in discarded vehicle tires in rural and urban habitats. Discarded tires were placed at 6 rural and 6 urban forested sites and sampled weekly for juvenile mosquitoes.

Technology-assisted instruction with teacher prompts on fraction multiplication word problems: A single-case design with visual analysis and Bayesian multilevel modeling.

This study examines the effects of technology-assisted instruction with teacher prompts on the ability to visualize and solve fraction multiplication word problems for four middle school students with learning disabilities. A multiple-probe design across participants, a type of single-case design, showed a functional relationship between the intervention and the targeted mathematical outcomes. Although there were some fluctuations over time, students demonstrated improvements from the baseline to intervention phases (Tau ranged from 0.

The Effect of Sampling Context on Preschoolers' Finite Verb Morphology Composite Scores.

Purpose: The finite verb morphology composite (FVMC) is a valid measure for charting children's tense development and for differentiating children with and without language impairment during preschool and early elementary years. However, it is unclear whether FVMC scores vary as a function of language sample elicitation contexts. The current study evaluated the performance on FVMC in preschool-aged children across different language sampling contexts.