72 results match your criteria: "Kent State University College of Podiatric Medicine[Affiliation]"
Front Physiol
October 2024
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, United States.
Metabolic acidosis (MAc)-an extracellular pH (pH) decrease caused by a [HCO ] decrease at constant [CO]-usually causes intracellular pH (pH) to fall. Here we determine the extent to which the pH decrease depends on the pH decrease vs the concomitant [HCO ] decrease. We use rapid-mixing to generate out-of-equilibrium CO/HCO solutions in which we stabilize [CO] and [HCO ] while decreasing pH (pure acidosis, pAc), or stabilize [CO] and pH while decreasing [HCO ] (pure metabolic/down, pMet↓).
View Article and Find Full Text PDFJ Wound Care
September 2024
Oregon Health & Science University, Portland, OR, US.
Objective: This case series examines the use of a multimodal wound matrix (MWM) trialled in a selection of clinical practice settings and on a variety of hard-to-heal wounds. The objective was to evaluate the effects of MWM and its performance in managing such wounds, regardless of clinical setting and ulcer type.
Method: Treatment of the MWM was conducted by independent wound care practitioners on wounds that were of >4 weeks duration.
J Wound Care
August 2024
Director of Wound Care Research, Kent State University College of Podiatric Medicine, Independence, Ohio, US.
Wounds
May 2024
Natrox Wound Care, Cambridge, UK.
Background: Sufficient oxygen is critical for multiple processes in wound healing. Nonhealing wounds have low tissue oxygen levels due to damaged microvasculature and comorbidities limiting tissue perfusion. Hypoxia may be reversed using continuous topical oxygen therapy (cTOT).
View Article and Find Full Text PDFJ Wound Care
March 2024
SerenaGroup Research Foundation, Cambridge, MA US.
TS is a consultant for Inotec AMD Ltd., UK. The authors have no other conflicts of interest to declare.
View Article and Find Full Text PDFImportance: Patients with kidney failure have an increased risk of diabetes-related foot complications. The benefit of regular foot and ankle care in this at-risk population is unknown.
Objective: To investigate foot and ankle care by podiatrists and the outcomes of diabetic foot ulcers (DFUs) in patients with kidney failure.
Background: The long-term chronic effect of radiotherapy is commonly referred to as LRTI. Clinical complications such as skin atrophy, tissue fibrosis, endothelial damage, ulcer formation, and compromised wound healing are common sequela. Despite advances in medicine over the past decade, there remains a need for effective treatments for LRTI skin necrosis and ulcerations.
View Article and Find Full Text PDFFoot (Edinb)
December 2023
Podiatric Medical Student, Kent State University College of Podiatric Medicine, Independence, OH, USA.
Foot (Edinb)
December 2023
Kent State University College of Podiatric Medicine, 6000 Rockside Woods Blvd, Independence, OH 44131, USA. Electronic address:
Eplasty
September 2023
Ocean State Foot and Ankle Specialists, Woonsocket, Rhode Island.
Background: Amputations in the diabetic foot are commonly associated with complications, including delayed wound healing, surgical site dehiscence, and the need for additional amputations. Use of a novel adhesive suture retention device (ASRD) has been previously shown to support improved linear closure outcomes. The purpose of this retrospective case review was to determine if the adoption of the ASRD in 5 podiatric surgical practices would reduce postoperative complications in patients with diabetes undergoing foot amputations including surgical site dehiscence and the need for additional amputation.
View Article and Find Full Text PDFJ Wound Care
August 2023
Clinic of Plastic, Hand and Aesthetic Surgery, Burn Center, BG Clinic Bergmannstrost, Halle (Saale, Germany); Medical University Halle, Outpatient and Operating Center, Martin-Luther University, Halle (Saale), Germany; University of Applied Science Anhalt, Institute of Applied Bioscience and Process Management, Head of Academic Wound Consultant Education Course, Koethen, Germany.
Background: Elevated bacterial bioburden and biofilm formation are common causes for delayed wound healing. Biofilm is an assemblage of surface-associated microbes enclosed in a self-produced matrix. Identifying and managing biofilm is a crucial component of successful wound care protocols.
View Article and Find Full Text PDFNeurochem Res
September 2023
Department of Neural and Behavioral Sciences, Penn State University College of Medicine, 500 University Drive H109, Hershey, PA, 17033, USA.
Foot (Edinb)
September 2023
Kent State University College of Podiatric Medicine, 6000 Rockside Woods Blvd. N., Independence, OH 44131, United States. Electronic address:
Background: When evaluating hallux valgus (HV) deformity with anteroposterior (AP) foot radiographs, the distal metatarsal articular angle (DMAA) has been the subject of frequent debate. Although a straightforward indicator of structural alignment of the distal first metatarsal articular surface, inter- and intraobserver measurements can vary widely. Alterations in the radiographic appearance of bony "structure" with positional changes of the foot/foot bones in HV deformities in no small part contributes to these inaccuracies.
View Article and Find Full Text PDFIntroduction: Plantar hallux wounds are common in patients with diabetic neuropathy. Several techniques, both surgical and nonsurgical, are designed to offload plantar wounds. However, controversy exists regarding which techniques are superior in terms of efficacy, safety, and longevity.
View Article and Find Full Text PDFJ Foot Ankle Surg
July 2023
Podiatric Surgery Resident, Mercy Regional Medical Center, Lorain, OH.
Wounds
January 2023
Clinic of Plastic, Hand and Aesthetic Surgery, Burn Center, BG Clinic Bergmannstrost, Halle (Saale), Germany; Medical University Halle, Outpatient and Operating Center, Martin-Luther University, Halle (Saale), Germany; University of Applied Science Anhalt, Institute of Applied Bioscience and Process Management, Head of Education Course "Academic Wound Consultant" Koethen, Germany.
The etiology of acute and chronic wounds goes beyond those often reported in the literature, including those with exposed structures, those in which the entire wound bed cannot be visualized, and patients who are not candidates for typical standard of care. Treatment options for these patients may be limited. TABCT is a viable option for these complex wound types and is not hindered by logistical, procedural, or patient factors.
View Article and Find Full Text PDFWounds
September 2022
Clinic of Plastic, Hand and Aesthetic Surgery, Burn Center, BG Clinic Bergmannstrost, Halle (Saale), Germany; Medical University Halle, Outpatient and Operating Center, Martin-Luther University, Halle (Saale), Germany; University of Applied Science Anhalt, Institute of Applied Bioscience and Process Management, Head of Education Course "Academic Wound Consultant" Koethen, Germany.
Complex or hard-to-heal wounds can be acute or chronic; the complexity is based on patient-specific local, systemic, and psychosocial factors. Use of autologous tissue can be a significant adjunct to wound closure. Grafts and flaps are the most common autologous tissue used in wound reconstruction.
View Article and Find Full Text PDFWound Manag Prev
July 2022
Certified Medical Writer, Scriptum Medica Medical Writing, University Place, Washington.
Background: Pretibial injury is common. Although the mechanism of injury may be minor, in a specific patient population, misdiagnosis and delay in appropriate treatment can lead to dire consequences. The ability to identify and properly treat these patients early has the potential to reduce the need for surgical intervention, hospitalization, and prolonged care.
View Article and Find Full Text PDFA growing body of evidence supports the use of topical oxygen therapy (TOT) in the treatment of diabetic foot ulcers (DFUs). In addition, anecdotal evidence suggests that topical oxygen may be effective in the treatment of other wound types. In May 2021, experts in the field of wound healing from across the US assembled in New Orleans for the inaugural Leaders in Wound Healing conference.
View Article and Find Full Text PDFExp Mol Pathol
April 2022
Department of Surgery, University of Wisconsin-Madison, USA 600 Highland Ave, Madison, WI 53792, USA; William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA; University of Wisconsin Carbone Cancer Center, UW Health University Hospital, 1111 Highland Ave, Madison, WI 53705, USA. Electronic address:
Low-grade anal dysplasia is a disease that can progress to high-grade anal dysplasia and eventually anal cancer if left untreated. Research has shown that low-grade anal dysplasia is marked by significant autophagic dysfunction. We hypothesized that systemic induction of autophagy, via phosphoinositide 3-kinase/mammalian target of rapamycin (PI3K/mTOR) inhibition, would be effective in preventing anal cancer development in human papillomavirus (HPV) mice (K14E6/E7) with established low-grade anal dysplasia.
View Article and Find Full Text PDFJ Foot Ankle Surg
September 2022
Kent State University College of Podiatric Medicine, Independence, OH.
Nonuremic calciphylaxis is a rare condition presenting with peripheral ischemic ulcerations. Calciphylaxis is the deposition of calcium and phosphate into arteriolar walls caused by exceeding their solubility range in the blood. It is most commonly seen in patients with end-stage renal disease; however, nonuremic calciphylaxis occurs in patients with normal or mildly impaired renal function.
View Article and Find Full Text PDFPLoS One
November 2021
Department of Biological Sciences, Nova Southeastern University, Ft. Lauderdale, Florida, United States of America.
Metaplasia is a well documented and deleterious effect of crude oil components on oysters. This reversible transformation of one cell type to another is a common response to petroleum-product exposure in molluscs. It has been shown experimentally in previous work that eastern oysters (Crassostrea virginica) exposed to petroleum products will exhibit metaplasia of digestive tissues.
View Article and Find Full Text PDFJ Foot Ankle Surg
January 2022
Associate Professor, Division of Foot and Ankle Surgery & Biomechanics, Kent State University College of Podiatric Medicine, Independence, OH.
Clin Podiatr Med Surg
July 2021
Adjunct Faculty, St. Vincent Charity Medical Center, Cleveland, OH, USA.