24 results match your criteria: "Kensington Vision and Research Institute[Affiliation]"
In-Office Suprachoroidal Viscopexy for Acute Rhegmatogenous Retinal Detachment.
JAMA Ophthalmol
December 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Importance: In-office suprachoroidal viscopexy (SCVEXY) is a relatively new procedure for rhegmatogenous retinal detachment (RRD), but minimal information is available regarding outcomes and safety.
Objective: To report outcomes with in-office SCVEXY for primary acute RRD.
Design, Setting, And Participants: This retrospective case series was conducted at St Michael's Hospital in Toronto, Ontario, Canada from June 2023 to February 2024 among consecutive patients with primary acute RRDs who presented with retinal tears that were reachable with the current in-office SCVEXY technique in the temporal or nasal retina.
Suprachoroidal Space in Rhegmatogenous Retinal Detachment Assessed with Optical Coherence Tomography: Implications for Potential Future Therapeutic Interventions.
Retina
November 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Purpose: To comprehensively investigate the suprachoroidal space (SCS) in the context of rhegmatogenous retinal detachment (RRD) using swept-source optical coherence tomography (SS-OCT).
Methods: We conducted a post hoc analysis of 90 consecutive patients with a primary RRD. Baseline SS-OCT scans were graded for the presence and thickness of the suprachoroidal space.
Morphologic Stages of Full-Thickness Macular Hole on Spectral-Domain OCT.
Ophthalmol Retina
October 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Objective: To describe the sequential morphological changes of the outer retina after full-thickness macular hole (FTMH) formation utilizing a novel, objective staging system based on OCT, and to determine its association with baseline visual acuity, duration of symptoms, and postoperative visual acuity at 3 months.
Design: Retrospective, observational, multicenter study.
Participants: Patients with idiopathic FTMH presenting to St.
Comparison of the Photoreceptor Mosaic Before and After Macular Hole Surgery With High-Resolution Adaptive Optics Imaging.
Am J Ophthalmol
October 2024
From the Department of Ophthalmology and Vision Sciences, University of Toronto (P.L.O., T.W., S.C.N., M.C.P., H.H., M.I., F.N., P.Y., R.H.M.), Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto (P.L.O., M.C.P., H.H., F.N., P.Y., R.H.M.), Toronto, Ontario, Canada; Kensington Vision and Research Institute (T.W., P.Y., R.H.M.), Toronto, Ontario, Canada. Electronic address:
Article Synopsis
- This study evaluated the photoreceptor mosaic in patients with idiopathic full thickness macular holes before and after surgery using adaptive optics imaging.* -
- Conducted at the Kensington Eye Institute, the research excluded patients with certain conditions and involved detailed measurements of cone density and regularity in the retina.* -
- Results showed a significant decrease in cone density and changes in spacing and dispersion three months post-surgery, demonstrating the effectiveness of adaptive optics for assessing retinal health.*
Long-Term Redetachment Rates of Pneumatic Retinopexy versus Pars Plana Vitrectomy in Retinal Detachment: A PIVOT Post Hoc Analysis.
Ophthalmol Retina
August 2024
Department of Ophthalmology, St. Michael's Hospital/Unity Health Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 7 Kensington Vision and Research Institute, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Purpose: To assess long-term redetachment rates of the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT).
Design: Randomized controlled trial.
Subjects: PIVOT trial participants.
Reattachment rate with pneumatic retinopexy versus pars plana vitrectomy for single break rhegmatogenous retinal detachment.
Br J Ophthalmol
December 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada
Article Synopsis
- This study compares the primary reattachment rate (PARR) of two treatments, pneumatic retinopexy (PnR) and pars plana vitrectomy (PPV), for patients with a specific type of retinal detachment.
- It included 162 patients, where PARR was shown to be similar: 88.2% for PnR and 90.9% for PPV, with PnR providing better visual acuity outcomes.
- The findings suggest that PnR can be considered a suitable first-line treatment for select patients, as it yields similar reattachment rates while enhancing visual recovery.
Inferior vitreous pathology imaged with ultra-wide-field OCT following pneumatic retinopexy.
Can J Ophthalmol
August 2024
St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada; Kensington Vision and Research Institute, Toronto, ON, Canada.. Electronic address:
Morphologic Features of Regulated vs. Dysregulated Rhegmatogenous Retinal Detachment Using Swept-Source Optical Coherence Tomography.
Am J Ophthalmol
December 2024
From the Department of Ophthalmology and Vision Sciences, University of Toronto (A.P., S.C.N., S.D., M.C.P., I.M.M.), Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto (A.P., S.C.N., S.D., M.C.P., I.M.M.), Toronto, Ontario, Canada; Kensington Vision and Research Institute (A.P., S.C.N., S.D., M.C.P., I.M.M.), Toronto, Ontario, Canada. Electronic address:
Objective: To describe varying morphological features of patients with RRD based on the extent of regulation of the subretinal space by the retinal pigment epithelium (RPE) pump using swept-source optical coherence tomography (SS-OCT).
Design: Prospective clinical cohort study.
Methods: Setting: St.
VALIDATION OF M-CHARTS FOR QUANTITATIVE ASSESSMENT OF METAMORPHOPSIA FOLLOWING RHEGMATOGENOUS RETINAL DETACHMENT REPAIR.
Retina
July 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Purpose: To validate the quantitative assessment of metamorphopsia in rhegmatogenous retinal detachment (RRD) using M-CHARTS by determining its correlation with subjective reporting of metamorphopsia with a validated metamorphopsia questionnaire (modified MeMoQ).
Methods: The Research Ethics Board approved a prospective observational study carried out at St. Michael's Hospital, Toronto, Canada.
Impact of Baseline Morphologic Stage of Rhegmatogenous Retinal Detachment on Postoperative Visual Acuity.
Ophthalmol Retina
July 2024
Department of Ophthalmology, St. Michael's Hospital/Unity Health Toronto, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Purpose: To evaluate the association of baseline morphologic stage of rhegmatogenous retinal detachment (RRD) using OCT with postoperative anatomic and visual acuity (VA) outcomes.
Design: Retrospective cohort study.
Subjects: Consecutive primary fovea-involving RRDs referred from January 2012 to September 2022.
POSTOPERATIVE PHOTORECEPTOR INTEGRITY AND ANATOMICAL OUTCOMES BASED ON PRESENTING MORPHOLOGIC STAGE OF RHEGMATOGENOUS RETINAL DETACHMENT.
Retina
May 2024
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Purpose: To evaluate outer retinal recovery on postoperative optical coherence tomography (OCT) based on presenting morphologic stage of rhegmatogenous retinal detachment (RRD).
Methods: Retrospective cohort of consecutive primary fovea-involving RRDs, referred from January 2012 to September 2022. Baseline OCTs were assessed for morphologic stage of RRD.
Pathophysiology of Secondary Macular Hole in Rhegmatogenous Retinal Detachment.
Invest Ophthalmol Vis Sci
October 2023
Department of Ophthalmology, St. Michael's Hospital/Unity Health Toronto, Toronto, Ontario, Canada.
Purpose: To describe the pathophysiology of secondary macular hole (MH) in rhegmatogenous retinal detachment (RRD).
Methods: A retrospective cohort of 360 consecutive primary fovea-off RRDs presenting to St. Michael's Hospital, Toronto, from January 2012 to September 2022 were included.
Histological changes in retinal detachment: A systematic review for the clinician.
Surv Ophthalmol
December 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Although there have been numerous innovations in the management of retinal detachment (RD) over the past decades, there is still limited understanding of the pathophysiological processes that take place before and after repair. Summarizing key concepts using animal studies may allow for a better assessment of common pre- and postoperative microstructural abnormalities in RD. We performed a systematic literature review on Ovid MEDLINE, EMBASE, and Cochrane Controlled Register of Trials from January 1968 to January 2022, searching animal or human studies reporting retinal histologic changes following primary or induced RD.
View Article and Find Full Text PDFIn-Office Suprachoroidal Viscopexy for Rhegmatogenous Retinal Detachment Repair.
JAMA Ophthalmol
October 2023
Department of Ophthalmology, St Michael's Hospital/Unity Health Toronto, Toronto, Ontario, Canada.
Importance: In-office suprachoroidal viscopexy (SCVEXY) is a minimally invasive technique for rhegmatogenous retinal detachment (RRD) repair that can be performed with no incision, no tamponade agent, and no positioning requirements. This technique has the potential to be a step forward in the armamentarium to treat RRDs.
Objective: To describe in-office SCVEXY for RRD repair.
Outer Retinal Hyperreflective Dots: A Potential Imaging Biomarker in Rhegmatogenous Retinal Detachment.
Ophthalmol Retina
December 2023
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital/Unity Health Toronto, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Purpose: To investigate hyperreflective dots (HRDs) on baseline OCT in rhegmatogenous retinal detachment (RRD).
Design: Retrospective cohort study.
Subjects: Consecutive primary fovea-off RRDs presenting between January 2012 and September 2022.
Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment in Elderly Patients.
Ophthalmol Retina
November 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Purpose: To assess clinical outcomes in elderly patients aged ≥ 75 years who underwent pneumatic retinopexy (PnR) for primary rhegmatogenous retinal detachment (RRD).
Design: Retrospective cohort study.
Subjects: Patients aged ≥ 75 years with primary RRD undergoing PnR.
Posterior Vitreous Assessment in Pneumatic Retinopexy using Swept-Source OCT.
Ophthalmol Retina
August 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Photoreceptor mosaic before and after macular hole surgery with RTX-1 adaptive optics retinal camera.
Can J Ophthalmol
October 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, ON; Kensington Vision and Research Institute, Toronto, ON; Faculty of Medicine, University of Toronto, Toronto, ON. Electronic address:
Pathophysiology of outer retinal corrugations: Imaging dataset and mechanical models.
Data Brief
April 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
This article presents high-resolution swept-source optical coherence tomography (SS-OCT) imaging data used to elaborate a mechanical model that elucidates the formation of outer retinal corrugations (ORCs) in rhegmatogenous retinal detachments (RRD). The imaging data shared in the repository and presented in this article is related to the research paper entitled "Outer Retinal Corrugations in Rhegmatogenous Retinal Detachment: The Retinal Pigment Epithelium-Photoreceptor Dysregulation Theory" (Muni et al., AJO, 2022).
View Article and Find Full Text PDFBACILLARY LAYER DETACHMENT AND ASSOCIATED ABNORMALITIES IN RHEGMATOGENOUS RETINAL DETACHMENT.
Retina
April 2023
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Purpose: To describe bacillary layer detachment and related abnormalities of the foveal bouquet in rhegmatogenous retinal detachment and assess their impact on photoreceptor recovery and full-thickness macular hole formation, using optical coherence tomography.
Methods: Prospective cohort of 93 consecutive patients with fovea-off rhegmatogenous retinal detachment presenting to St. Michael's Hospital from January 2020 to April 2022, with gradable preoperative foveal optical coherence tomography.
Morphologic Stages of Rhegmatogenous Retinal Detachment Assessed Using Swept-Source OCT.
Ophthalmol Retina
May 2023
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Institute, Toronto, Ontario, Canada. Electronic address:
Purpose: To describe the sequential morphologic changes after rhegmatogenous retinal detachment (RRD) utilizing a novel, objective, and clinically relevant staging system based on swept-source OCT (SS-OCT) and determine its association with the duration of fovea-off and postoperative visual acuity (VA).
Design: Prospective cohort study.
Subjects: Consecutive patients with primary fovea-involving RRD referred to St.
Outer Retinal Corrugations in Rhegmatogenous Retinal Detachment: The Retinal Pigment Epithelium-Photoreceptor Dysregulation Theory.
Am J Ophthalmol
January 2023
Department of Chemical Engineering and Applied Chemistry (M.N.D., A.R.), University of Toronto, Toronto, Ontario, Canada.
Purpose: Outer retinal folds occur when outer retinal corrugations (ORCs) persist after retinal reattachment with worse functional outcomes. We investigate the pathophysiology of ORCs in vivo.
Design: Prospective cohort study.
Impact of tamponade agent on retinal displacement following pars plana vitrectomy for rhegmatogenous retinal detachment repair: a computer simulation model.
Acta Ophthalmol
November 2022
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Understanding the mechanism of retinal displacement following rhegmatogenous retinal detachment repair: A computer simulation model.
Acta Ophthalmol
August 2022
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Purpose: Retinal displacement is common following rhegmatogenous retinal detachment (RRD) repair. A computer simulation was developed to assess forces applied by a gas tamponade of various sizes in the setting of pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV).
Design: Computer simulation model.