7 results match your criteria: "Keio University Faculty of Medicine[Affiliation]"

In vivo confocal microscopy (IVCM) is a non-invasive imaging technique used to visualize the layers of the cornea and conjunctiva in real time. In patients with atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC), this technology can be useful in diagnosing and monitoring the disease, as well as evaluating the efficacy of treatments. IVCM can reveal subclinical abnormalities in the corneal and conjunctival epithelium such as inflammatory cell infiltrates and tissue damage, which can provide insight into the pathogenesis of AKC.

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Article Synopsis
  • Doctors studied what causes brain bulges called intracranial aneurysms (IAs), which can lead to serious bleeding.
  • They found that many of these IAs have changes in certain genes that affect how the cells work, discovering 16 mutated genes in 92% of the cases they looked at.
  • One gene mutation was shown to make blood vessels grow bigger in mice, suggesting that these findings could help create new treatments to prevent or fix IAs.
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Comparison of Long-Term Corneal Astigmatic Changes After Cataract Surgery in Eyes With Superior or Horizontal Clear Corneal Incisions.

Am J Ophthalmol

October 2022

Department of Ophthalmology (S.H., K.N.), Keio University Faculty of Medicine, Tokyo, Japan; Hayashi Eye Hospital (M.Y., K.H., K.N.), Fukuoka, Japan.

Purpose: To compare long-term corneal astigmatic changes after stabilization of surgically induced astigmatism (SIA) subsequent to phacoemulsification between eyes that underwent superior clear corneal incision (CCI) or horizontal CCI.

Design: Retrospective, comparative case series.

Methods: We examined the anterior corneal astigmatism of eyes that underwent a 2.

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Purpose: To compare the progression of posterior vitreous detachment (PVD) between eyes that underwent cataract surgery and eyes that did not undergo surgery in non-highly myopic patients.

Methods: One-hundred twenty-five eyes of 125 patients scheduled for phacoemulsification and 125 eyes of 125 age-matched patients who did not undergo surgery were enrolled. PVD status was evaluated using swept-source optical coherence tomography at 2 days (baseline), and 1, 3, 6, and 12 months postoperatively, and classified into five stages: 0 (no), 1 (paramacular), 2 (perifoveal), 3 (peripapillary), and 4 (complete).

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Purpose: To compare short-term changes in refractive prediction error (PE) after phacoemulsification among eyes receiving different types of single-piece acrylic intraocular lenses (IOLs).

Design: Randomized clinical trial.

Methods: A total of 195 eyes of 195 patients scheduled for implantation of a single-piece acrylic IOL were randomly assigned to receive 1 of 3 IOLs: 1) an Alcon model SN60WF, 2) a Hoya model XY-1, or 3) an AMO model ZCB00V.

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A better understanding of the pathophysiology and etiology of dry eye disease leads to more efficient management and treatment of the disease process. However, there is substantial variation among both clinicians and countries in terms of dry eye treatment modalities. The latest 2017 International Dry Eye Workshop II report aimed to reduce these differences and emphasized the use of a stepped care algorithm.

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The efficacy and side effects of various antiepileptic drugs (AEDs), especially pyridoxine, ACTH and valproate sodium (VPA), in the treatment of West syndrome were reviewed. ACTH remains to be the most effective treatment for West syndrome. However, there are significant adversive effects with prolonged ACTH therapy.

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