Geospatial monitoring and human health risk assessment of pharmaceutical residues in groundwater and surface water in Kampala and Mbarara Districts, Uganda.

This study investigated the occurrence, concentration and human health risks of five pharmaceutical residues-metronidazole, sulfamethoxazole, ciprofloxacin, carbamazepine, and caffeine-in groundwater and surface water samples from Kampala and Mbarara districts of Uganda. The present study also employed techniques of remote sensing and geographic information system (GIS); thereby, emphasizing the importance of thematic mapping, land use classification, and spatial buffering to evaluate pharmaceutical contaminants in an environmental setting. The risk quotient (RQ) approach was also employed to assess the risk of exposure to the pharmaceutical contaminants.

Exploring of Chemical Profile and Biological Activities of Three Ocimum Species From Comoros Islands: A Combination of In Vitro and In Silico Insights.

Ocimum species have a great interest in different traditional medicinal systems. This study examined the chemical composition, antioxidant properties, enzyme inhibitory effects, and antibacterial and antifungal activities of the aerial parts of Ocimum gratissimum, Ocimum americanum, and Ocimum basilicum from the Comoros Islands. The extracts were analyzed using high-performance liquid chromatography-mass spectrometry (HPLC-MS) to determine their chemical composition.

Computational models for improving surveillance for the early detection of direct introduction of cassava brown streak disease in Nigeria.

Cassava is a key source of calories for smallholder farmers in sub-Saharan Africa but its role as a food security crop is threatened by the cross-continental spread of cassava brown streak disease (CBSD) that causes high yield losses. In order to mitigate the impact of CBSD, it is important to minimise the delay in first detection of CBSD after introduction to a new country or state so that interventions can be deployed more effectively. Using a computational model that combines simulations of CBSD spread at both the landscape and field scales, we model the effectiveness of different country level survey strategies in Nigeria when CBSD is directly introduced.

Does the job performance of academics' influence burnout and psychological counselling? A comparative analysis amongst high-, average-, low-, and non-performers.

Background: Extensive research has been conducted treating burnout as an independent variable and performance as a dependent variable to proffer possible solutions to burnout and job performance among academics. Despite this, the burnout crises persist and are exacerbated by the ongoing global proliferation of higher education. Acknowledging this, the current study explored whether performance may contribute to the emergence of burnout.

Whether academics' job performance makes a difference to burnout and the effect of psychological counselling-comparison of four types of performers.

Treating burnout as an independent variable while performance is the dependent variable, earlier studies revealed that job burnout experienced by academics adversely affects how well they perform. Whether performance may contribute to the emergence of burnout is yet to be analyzed-it is an issue investigated in this paper. Readjusting the nature of the variables, this quantitative study adopted group regression and it discovered that the performance of academics instead regulates their burnout without making performance a consequence of burnout-a new dynamic that challenges the earlier assumption.

Ameliorative Effect of Against Dinitrophenylhydrazine Induced Hyperbilirubinemia in Wistar Albino Rats.

Background: popularly known as gawo in Hausa, is traditionally used to treat jaundice in Zuru emirate of Kebbi State. Herein, the ameliorative effect of against 2.4-dinitrophenylhydrazine-induced hyperbilirubinemia in Wistar albino rats was investigated.

Epidemiology of multidrug-resistant Klebsiella pneumoniae infection in clinical setting in South-Eastern Asia: a systematic review and meta-analysis.

The rising prevalence of multidrug-resistant (MDR) and extended-spectrum beta lactamase-resistant (ESBL) Klebsiella pneumoniae (K. pneumoniae) is an important global public health challenge. This threat is even more pertinent in clinical settings.

Sustainable application of electrocatalytic and photo-electrocatalytic oxidation systems for water and wastewater treatment: a review.

Wastewater treatment and reuse have risen as a solution to the water crisis plaguing the world. Global warming-induced climate change, population explosion and fast depletion of groundwater resources are going to exacerbate the present global water problems for the forthcoming future. In this scenario, advanced electrochemical oxidation process (EAOP) utilising electrocatalytic (EC) and photoelectrocatalytic (PEC) technologies have caught hold of the interest of the scientific community.

Occurrence, environmental impact and fate of pharmaceuticals in groundwater and surface water: a critical review.

In many nations and locations, groundwater serves as the population's primary drinking water supply. However, pharmaceuticals found in groundwater and surface waters may affect aquatic ecosystems and public health. As a result, their existence in natural raw waters are now more widely acknowledged as a concern.

Comparative evolutionary analyses of eight whitefly Bemisia tabaci sensu lato genomes: cryptic species, agricultural pests and plant-virus vectors.

Background: The group of > 40 cryptic whitefly species called Bemisia tabaci sensu lato are amongst the world's worst agricultural pests and plant-virus vectors. Outbreaks of B. tabaci s.

An insight into the mechanisms of action of selected bioactive compounds against epigenetic targets of prostate cancer: implications on histones modifications.

Prostate cancer is a leading cause of morbidity and mortality among men globally. In this study, we employed an in silico approach to predict the possible mechanisms of action of selected novel compounds reported against prostate cancer epigenetic targets and their derivatives, exhausting through ADMET profiling, drug-likeness, and molecular docking analyses. The selected compounds: sulforaphane, silibinin, 3, 3'-diindolylmethane (DIM), and genistein largely conformed to ADMET and drug-likeness rules including Lipinski's.

The Impact of the First and Second Waves of COVID-19 Pandemic in Nigeria.

In recent times, the COVID-19 pandemic has been the subject of global concern. It has so far claimed over 5.4 million lives globally, with over 291 million cases recorded worldwide as of 5 January 2022.

Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria.

Introduction: For decades, viral diseases have been treated using medicinal plants and herbal practices in the northern part of Nigeria. Though scarcely investigated, these medicinal plants could serve as potential sources for novel antiviral drugs against emerging and remerging viral diseases. Therefore, this study is aimed at investigating the medicinal practices and plants used to treat emerging and re-emerging viral diseases including hepatitis, poliomyelitis, monkeypox, smallpox, yellow fever, Lassa fever, meningitis, and COVID-19 in some northern states; Katsina, Kebbi, Kwara and Sokoto states.

(L.) DC.: is a potential source for the exploitation of anticancer agents.

(L.) DC. is a weed plant commonly used for the treatment of eczema.

A systematic review and meta-analysis of the prevalence of in South-East Asia; a one-health approach of human-animal-food-environment.

is an important foodborne intracellular pathogen. The pathogen is the primary cause of human Listeriosis. The main source of human Listeriosis is through consumption of contaminated food products.

Mixed convection flow of an electrically conducting viscoelastic fluid past a vertical nonlinearly stretching sheet.

The study of hydromagnetic mixed convection flow of viscoelastic fluid caused by a vertical stretched surface is presented in this paper. According to this theory, the stretching velocity varies as a power function of the displacement from the slot. The conservation of energy equation includes thermal radiation and viscous dissipation to support the mechanical operations of the heat transfer mechanism.

Women's Footprint in Anti-Doping Sciences: A Bibliometric Approach to Research Impact.

Bibliometrics, the exploitation of large-scale publication data, is a facile approach to explore gender-related trends, especially gender equality in academic publishing and authorship. For the first time, this study aims to investigate the gender-related trends in anti-doping sciences to (1) explore the relational structure of gender aspects of authorial, topical, and methodological features, (2) give recognition to women's contribution to anti-doping research, and (3) identify unique "gendered" potentials for advancing anti-doping research. To deliver on these aims, we employed bibliometric tools to publication records in anti-doping.

Chitinolytic and Antagonistic Activity of Isolated from Fadama Soil against Phytopathogenic Fungi.

Chitinases which degrade chitin have attracted attention as biological antifungal agents. The purpose of this study is to isolate from Fadama soil and assess its chitinolytic and antagonist potential against phytopathogenic fungi for application as biocontrol agent. were isolated from Fadama soil.

Homing in on Endogenous Badnaviral Elements: Development of Multiplex PCR-DGGE for Detection and Rapid Identification of Badnavirus Sequences in Yam Germplasm.

Viruses of the genus (family ) are double-stranded DNA-reverse transcribing (dsDNA-RT) plant viruses and have emerged as serious pathogens of tropical and temperate crops globally. Endogenous badnaviral sequences are found integrated in the genomes of several economically important plant species. Infection due to activation of replication-competent integrated copies of the genera , and has been described.

Effects of Corruption Control on the Number of Undernourished People in Developing Countries.

Developing countries will be home to 85% of the world's population by 2030. Hence, it is important to ensure food security for them. This effort is not easy, as the number of undernourished people (NUP) in the world has increased.

Epigenetic modifications associated with genes implicated in cytokine storm: The potential biotherapeutic effects of vitamins and minerals in COVID-19.

Cytokine storm is a phrase used to refer to an abrupt upsurge in the circulating levels of various pro-inflammatory cytokines, causing increased stimulation and activity of immune cells during disease conditions. The binding of pattern recognition receptors to pathogen-associated molecular patterns during COVID-19 infection recruits response machinery involving the activation of transcription factors and proteins required for a robust immune response by host cells. These immune responses could be influenced by epigenetic modifications as evidenced by significant variations in COVID-19 pathophysiology and response to therapy observed among patients across the globe.

Prevalence and Predictive Factors of Hypertension Among People Living With HIV in Kebbi State, Nigeria: A Cross-sectional Study.

The estimated number of people living with HIV (PLWH) globally in 2018 was 38 million, with sub-Saharan Africa accounting for 70%. Antiretroviral therapy has reduced morbidity among PLWH and has resulted in HIV now being considered a manageable chronic disease rather than a fatal one. The increase in the survival rate of PLWH has led to the emergence of chronic diseases, especially hypertension.

Current State of COVID-19 Pandemic in Africa: Lessons for Today and the Future.

This study is a cross-sectional, observational analysis of the COVID-19 pandemic in Africa, to understand the progression of the disease across the continent. Published data on COVID-19 from 20 January 2020 to 21 June 2021 were obtained and analyzed. Case fatality ratios, as well as case growth rates and other indices were computed.

INCIDENCE OF RIFAMPICIN-RESISTANCE PRESUMPTIVE CASES AMONG OUTPATIENTS IN KEBBI STATE, NIGERIA.

Background: The present study determined the incidence of rifampicin resistance among outpatients at the General Hospital Yauri, Kebbi State, Nigeria.

Materials And Methods: The study is a cross-sectional study conducted from February 2018 to October 2019. Sociodemographic data were collected from hospital registration books.