Phosphineoxide-Chelated Europium(III) Nanoparticles for Ceftriaxone Detection.

The present work demonstrates the optimization of the ligand structure in the series of bis(phosphine oxide) and β-ketophosphine oxide representatives for efficient coordination of Tb and Eu ions with the formation of the complexes exhibiting high Tb- and Eu-centered luminescence. The analysis of the stoichiometry and structure of the lanthanide complexes obtained using the XRD method reveals the great impact of the bridging group nature between two phosphine oxide moieties on the coordination mode of the ligands with Tb and Eu ions. The bridging imido-group facilitates the deprotonation of the imido- bis(phosphine oxide) ligand followed by the formation of tris-complexes.

Analysis of Aluminum Oxides Submicron Particle Agglomeration in Polymethyl Methacrylate Composites.

Agglomeration of distributed particles is the main problem in polymer composites reinforced with such particles. It leads to a decrease in mechanical performance and its poor reproducibility. Thus, development of methods to address the agglomeration of particles is relevant.

Biology of the SARS-CoV-2 Coronavirus.

New coronavirus infection causing COVID-19, which was first reported in late 2019 in China, initiated severe social and economic crisis that affected the whole world. High frequency of the errors in replication of RNA viruses, zoonotic nature of transmission, and high transmissibility allowed betacoronaviruses to cause the third pandemic in the world since the beginning of 2003: SARS-CoV in 2003, MERS-CoV in 2012, and SARS-CoV-2 in 2019. The latest pandemic united scientific community and served as a powerful impetus in the study of biology of coronaviruses: new routes of virus penetration into the human cells were identified, features of the replication cycle were studied, and new functions of coronavirus proteins were elucidated.

Structural, Magnetic and Vibrational Properties of Van Der Waals Ferromagnet CrBr at High Pressure.

The crystal and magnetic structures of van der Waals layered ferromagnet CrBr3 were studied using X-ray powder diffraction and neutron powder diffraction at pressures up to 23 GPa at ambient temperature and up to 2.8 GPa in the temperature range 6-300 K, respectively. The vibration spectra of CrBr3 were studied using Raman spectroscopy at pressures up to 23 GPa at ambient temperature.

Zero Gravity is a Factor that Induces Negative Changes in Myelinated Fibers of the Spinal Tracts.

The development of hypogravitational motor syndrome is an essential negative consequence of weightlessness for humans; an important role in the pathogenesis of this syndrome is played by changes in axons of the spinal tracts. Myelinated fibers and transcriptome of the spinal cord were studied in mice exposed to hypogravity during a 30-day flight on a biosatellite. Morphometric analysis of myelinated fibers of the spinal tracts showed a decrease in the thickness of the myelin sheath.

The Effect of α-Adrenoreceptors Blockade on the Isolated Rat Heart during the Formation of Sympathetic Innervation.

We studied the effects of the α-adrenergic receptor antagonist yohimbine (10-10 M) on inotropy, chronotropy, and coronary flow in the Langendorff-isolated heart from 3- and 6-week-old rats. Yohimbine affected all the studied functional parameters of the isolated heart. The force of contraction of the left ventricular myocardium, HR, and coronary flow decreased at all studied concentrations of the antagonist.

A new triphenylphosphonium-conjugated amphipathic cationic peptide with improved cell-penetrating and ROS-targeting properties.

We study for the first time whether triphenylphosphonium (TPP) moiety can improve cellular delivery and redox properties of amphipathic cationic peptides based on YRFK/YrFK cell-penetrating and cytoprotective motif. TPP moiety was found to increase reducing activity of both stereoisomeric peptides in solution and on electrode surface in association with TPP-mediated intramolecular interactions. Among TPP-conjugated peptides, newly synthesized TPP3-YrFK featured both increased antioxidant efficacy and proteolytic resistance.

[Crista galli pnevmatization: prevalence and clinical significance].

Objective: Determine the frequency of (crest of the rooster) pneumatization and the presence of communication of the pneumatized with the paranasal sinuses.

Material And Methods: Computed tomography data of the paranasal sinuses of 251 patients. The patients' age ranged from 23 to 70 years.

Identification of the novel HLA-A*02:01:204 allele by next-generation sequencing.

The novel HLA-A*02:01:204 allele was characterized using next generation sequencing technology.

Growth Parameters of Various Green Microalgae Species in Effluent from Biogas Reactors: The Importance of Effluent Concentration.

The use of liquid waste as a feedstock for cultivation of microalgae can reduce water and nutrient costs and can also be used to treat wastewater with simultaneous production of biomass and valuable products. This study applied strategies to treat diluted anaerobic digester effluent (ADE) as a residue of biogas reactors with moderate (87 ± 0.6 mg L; 10% ADE) and elevated NH-N levels (175 ± 1.

SARS-CoV-2 Antibody Effectiveness Is Influenced by Non-Epitope Mutation/Binding-Induced Denaturation of the Epitope 3D Architecture.

The public health threat from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to intensify with emerging variants of concern (VOC) aiming to render COVID-19 vaccines/infection-induced antibodies redundant. The SARS-CoV-2 spike protein is responsible for receptor binding and infection of host cells making it a legitimate antibody target. Antibodies mostly target epitopes in the receptor binding domain (RBD).

Identification of the novel HLA-C*05:269 allele by next-generation sequencing.

The novel HLA-C*05:269 allele was characterized using next-generation sequencing technology.

[The effectiveness of short and prolonged course treatment of anxiety with Anvifen].

Objective: To determine the effectiveness of the treatment of anxiety disorder with Anvifen (aminophenylbutyric acid) in a short (21 days) and prolonged (60 days) course of treatment.

Material And Methods: Patients were randomly divided into two groups: a short course (21 days) of treatment with Anvifen (group 1) and a prolonged course (60 days) of treatment with Avifen (group 2). In each group, patients were divided into age subgroups: 20-40 years old (1a - =30, mean age 32 [21; 39], 2a - =30, mean age 33 [23; 38] years) and 41-70 years (1b - =30, mean age 62 [51; 67] years; 2b - =30, mean age 60 [51; 68] years).

The novel HLA-C*04:441:01:02 allele was identified in three unrelated bone marrow donors.

The novel HLA-C*04:441:01:02 allele was characterized using next generation sequencing technology.

Identification of the novel HLA alleles: HLA-A*30:201, HLA-B*51:364 and HLA-C*08:241.

Three novel HLA alleles HLA-A*30:201, HLA-B*51:364 and HLA-C*08:241 alleles detected during routine next generation sequencing.

The novel HLA-A*03 allele, HLA-A*03:440, identified in a potential hematopoietic stem cell donor.

The novel HLA-A*03:440 allele was characterized using next generation sequencing technology.

The novel HLA-A*11 allele, HLA-A*11:01:109:02, identified by next generation sequencing.

The novel HLA-A*11:01:109:02 allele was characterized using next generation sequencing technology.

Characterization of the novel alleles: HLA-A*31:212, HLA-B*50:01:20 and HLA-C*03:593.

Three novel HLA alleles HLA-A*31:212, HLA-B*50:01:20 and HLA-C*03:593 alleles detected during routine next generation sequencing.

Identification and characterization of the novel HLA-A*23:122 allele by next-generation sequencing.

The novel HLA-A*23:122 allele was characterized using next generation sequencing technology.

Teachers' attitudes to cultural diversity: Results from a qualitative study in Russia and Taiwan.

This study examined elementary school teachers' attitudes toward immigrant students and their families in Russia and Taiwan. Qualitative methodology was used for data collection. Teachers' attitudes and conceptual orientations toward cultural diversity in the classroom were identified.

Analysis of herpesvirus infection and genome single nucleotide polymorphism risk factors in multiple sclerosis, Volga federal district, Russia.

Multiple sclerosis (MS) is a heterogeneous disease where herpesvirus infection and genetic predisposition are identified as the most consistent risk factors. Serum and blood samples were collected from 151 MS and 70 controls and used to analyze circulating antibodies for, and DNA of, Epstein Barr virus (EBV), human cytomegalovirus (HCMV), human herpes virus 6 (HHV6), and varicella zoster virus (VZV). The frequency of selected single nucleotide polymorphisms (SNPs) in MS and controls were studied.

Identification of the novel HLA-C*02:212 allele detected in a potential hematopoietic stem cell donor.

The novel HLA-C*02:212 allele was characterized using next generation sequencing technology.

Recognition of the novel HLA-C*07:1002 allele identified in a potential hematopoietic stem cell donor.

The novel HLA-C*07:1002 allele was characterized using next-generation sequencing technology.

Characterization of four novel HLA-B alleles: HLA-B*07:02:92, -B*40:02:36, -B*18:220, -B*18:221.

Four novel HLA-B alleles HLA-B*07:02:92, -B*40:02:36, -B*18:220, and -B*18:221 alleles detected during routine next generation sequencing.