1 results match your criteria: "Kazan Center of the Russian Academy of Sciences[Affiliation]"
Synthesis and antimycobacterial activity of triterpeni≿ A-ring azepanes.
Eur J Med Chem
January 2018
Arbuzov Institute of Organic and Physical Chemistry, Kazan Center of the Russian Academy of Sciences, Arbuzova st., 8, 420088, Kazan, Russian Federation.
A series of A-ring azepanones and azepanes derived from betulonic, oleanonic and ursonic acids was synthesized and evaluated for their in vitro antimycobacterial activities against M. tuberculosis (MTB) H37Rv and SDR-TB in the National Institute of Allergy and Infectious Diseases. Triterpenic A-azepano-28-hydroxy-derivatives were synthesized by the reduction with LiAlH of triterpenic azepanones available from the Beckmann rearrangement of the corresponding C3-oximes.
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