11,240 results match your criteria: "Kazakhstan; M.A. Aitkhozhin's Institute of Molecular Biology and Biochemistry[Affiliation]"

Article Synopsis
  • Pseudochorthippus geminus is redefined and depicted using specimens collected from southern Kazakhstan and northern Kyrgyzstan.
  • The research includes the analysis of male calling songs of both P. geminus and P. parallelus, highlighting differences in their song patterns.
  • Although the songs suggest that P. geminus and P. parallelus are distinct species, their physical traits are subtle and may not be reliable for identifying them.
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Article Synopsis
  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
  • The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
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Objectives: This study aims to analyze the impact of COVID-19 on pregnancy and labor, focusing on its effects on maternal and child health. The research explores the relationships between coronavirus infection and clinical and laboratory parameters, as well as the risks of pregnancy complications and adverse birth outcomes.

Methods: The study involved 60 pregnant women diagnosed with COVID-19.

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Extreme ecosystems are a rich source of specialized metabolites that can overcome multidrug resistance. However, the low efficiency of traditional exploratory research in discovering new antibiotics remains a major limitation. We hypothesized that actinomycetes may have the ability to produce antibiotics in the extremes of a changing natural environment.

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Background: Rupture of an abdominal aortic aneurysm (AAA) is a life-threatening emergency, with untreated cases nearing a 100% mortality rate. This case presents a rare complication of AAA rupture with an infected retroperitoneal hematoma, emphasizing the importance of timely diagnosis and a multidisciplinary approach.

Case Presentation: A 59-year-old male presented with lower back pain, fever, and difficulty moving, persisting for three weeks.

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Nanostructured materials have been suggested to be used as a source of dietary zinc for livestock animals. In this study, we assessed the cytotoxicity of newly synthesized nanostructured zinc carbonate hydroxide (ZnCH) Zn(CO)(OH)microflakes. Cytotoxicity of the microflakes was assessed against murine L929 cell line and rat mature erythrocytes.

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miR158a negatively regulates plant resistance to Phytophthora parasitica by repressing AtTN7 that requires EDS1-PAD4-ADR1 complex in Arabidopsis thaliana.

Plant J

January 2025

State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China.

Small RNAs are involved in diverse cellular processes, including plant immunity to pathogens. Here, we report that miR158a negatively regulates plant immunity to the oomycete pathogen Phytophthora parasitica in Arabidopsis thaliana. By performing real-time quantitative PCR, transient expression, and RNA ligase-mediated 5' rapid amplification of cDNA ends assays, we demonstrate that miR158a downregulates AtTN7 expression by cleaving its 3'-untranslated region.

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The article embarks upon a study of political Sufism in contemporary Kazakhstan and patterns of religious continuity through an examination of Islamic manifestations that stretch back centuries, juxtaposed with the current state religious policy. It examines the role of the Muftiate's "official Islam" in shaping the life of religious communities, exploring the intricate interplay between religious identity, secularism, and public perception in the post-Soviet landscape. The author employed a multi-faceted research approach, integrating historical analysis, policy examination, and an ethnographic study of contemporary religious dynamics in the country.

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This study aimed to elucidate the effects of various nutritional supplements on the physical, structural and sensory attributes of low-fat yogurt derived from camel milk, with the longer-term objective of enhancing its appeal and suitability for elderly consumers. Fresh camel milk was obtained from an Australian farm. Two yogurt variants were created: plain yogurt (CMY) and yogurt with added fructooligosaccharides, microbial transglutaminase (a ubiquitous food additive with potential health risks), apple pectin and linseed oil (CMYWA).

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Fruit and vegetables are a basic component of the human diet. European pesticide monitoring data indicated recently that in one sample multiple residues were detected which might be a public concern. Thus, the challenge of the present study was to assess the potential dietary exposure of the most critical EU children and adults subpopulations consuming fruit and vegetables.

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Most of the world's mountains are distributed across national boundaries. However, due to the sovereignty of national boundaries, conservation plans between neighboring countries are often uncoordinated. Against the backdrop of impending environmental changes, transboundary mountain ecosystems and biodiversity face significant threats.

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Article Synopsis
  • * Recent studies highlight its pharmacological properties, particularly those of methyl antcinate A (MAA), which shows significant anti-cancer, anti-inflammatory, and gastro-protective effects.
  • * There is a need for further research and clinical trials to better understand MAA's anti-tumor effects and to explore the structure-activity relationships of antcins for potential therapeutic applications.
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The study of working conditions and the quality of life (QoL) of medical workers has not lost its relevance worldwide. This highlights the need to understand the many aspects of life that may characterize physician performance and satisfaction with working conditions. This is extremely important for providing quality and safe medical care.

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Background: Artificial intelligence integration into healthcare has gained significant attention in recent years, with its use ranging from disease diagnosis to surgical assistance. While artificial intelligence's potential to improve patient outcomes and optimise patient care is undeniable, concerns regarding privacy, transparency, and the potential for medical errors persist. To take full advantage of artificial intelligence's transformative abilities, understanding patient perceptions and attitudes towards its integration into medicine is crucial for ethical considerations and health outcomes.

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Objectives: This study aimed to compare mental healthcare services for older adults aged ≥65 years among countries in World Psychiatric Association (WPA) Zone 10.

Methods: A culturally sensitive questionnaire was developed and sent to the presidents of national psychiatric associations of the eight countries in WPA Zone 10 (Armenia, Azerbaijan, Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, and Uzbekistan).

Results: Psychiatric associations of six countries responded to the questionnaire (Armenia and Moldova did not respond).

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The construction industry significantly impacts the environment through natural resource depletion and energy consumption, leading to environmental degradation. Circular Economy (CE) material efficiency strategies-such as material reuse, design for disassembly, prefabrication, and recycling-offer promising solutions for reducing resource consumption and waste. This paper explores stakeholders' perspectives on the costs and benefits of implementing CE material efficiency strategies in the construction industry, using the 3-R (Reduce, Reuse, Recycle) framework.

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Rabbit heart bioartificial tissue: perfusion decellularization and characterization.

Biomed Phys Eng Express

December 2024

Nazarbayev University, School of Engineering and Digital Sciences, Department of Chemical and Materials Engineering, Astana, Kazakhstan.

Despite new approaches in the treatment of cardiovascular disease (CVD) such as percutaneous coronary intervention, coronary artery bypass graft, and left ventricular assist devices, which cannot fully compensate for the effectiveness of the original heart, heart transplantation still remains as the most effective solution. A growing body of literature recognizes the importance of developing a whole heart constructed from living tissues to provide an alternative option for patients suffering from diseases of the cardiovascular system. A potential solution that shows a promise is to generate cell-free, i.

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, commonly known as garlic chives, is an underutilized species despite its significant culinary value for its mild garlic flavor and therapeutic potential due to the presence of sulphur-containing compounds with antimicrobial, anti-inflammatory, and antioxidant properties. This study assessed the cultivation potential of in the non-traditional agro-climatic region of the Western Ghats, focusing on the effects of cultivars and seasonal variations on growth, yield, and quality in two-year field trials. Among the accessions tested, Kazakhstan CGN-1587 demonstrated the highest yield, producing 157.

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Objective: To quantify and compare concurrent within-person trends in lifestyle risks, nutrition status, and drivers of food choice among urban migrants in Central Asia.

Design: We collected panel data on household structure, drivers of food choice, nutrition knowledge, and diverse measures of nutrition status and lifestyle risk from urban migrants at 0, 3, 6, and 9 months using harmonized methodology in two cities. Trends were analyzed using mixed-effects models and qualitatively compared within and between cities.

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Introduction: Currently, limited data are available on long-term use of dupilumab to treat atopic dermatitis (AD) in a multinational real-world setting. The aim of this analysis was to report the interim 1-year data for patients with AD enrolled in the GLOBOSTAD registry, including treatment patterns, dupilumab effectiveness and safety, and healthcare burden.

Methods: GLOBOSTAD is an ongoing, 5-year, multinational, prospective, observational study of adult/adolescent (aged ≥ 12 years at baseline) patients with AD who initiated dupilumab in real-world settings according to their local country-specific prescribing guidelines.

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Background And Aim: In some countries, the application of digital technologies in dairy cattle breeding is still under development. This study aimed to investigate the use of digital technologies in dairy cattle breeding to improve the reproductive function of cows and heifers in three northern regions of Kazakhstan.

Materials And Methods: This study explores the application of Austrian smaXtec bolus sensors, which enable the daily monitoring of the reproductive functions of cows and heifers in livestock.

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Background: The diagnosis of ulcerative colitis (UC) today is limited to a small number of biomarkers. Trimethylamine-N-oxide (TMAO) is the product of reactions resulting from the degradation of dietary-free choline, phosphatidylcholine, and carnitine metabolism by the intestinal microbiota. Earlier studies showed his involvement in the pathogenesis of UC.

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