462 results match your criteria: "Kayseri City Hospital[Affiliation]"

Purpose: To evaluate the compatibility and readability of ChatGPT-4 in providing responses to common inquiries about strabismus and amblyopia.

Materials And Methods: A series of commonly asked questions were compiled, covering topics such as the definition, prevalence, diagnostic approaches, surgical and non-surgical treatment alternatives, postoperative guidelines, surgery-related risks, and visual prognosis associated with strabismus and amblyopia. Each question was asked three times on the online ChatGPT-4 platform both in English and French, with data collection conducted on February 18, 2024.

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  • - The study focuses on improving transitional care for adolescents with juvenile idiopathic arthritis (JIA) as they move to adult healthcare systems, suggesting the need for tailored programs in each country.
  • - A Delphi study involving adolescents, parents, and clinicians was conducted to gather expert opinions and identify key components of transitional care, with significant participation in the initial surveys.
  • - While a consensus was reached on essential transitional care issues for JIA patients, further agreement is needed on practical applications of a final checklist to enhance care in Turkey.
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Background: Earthquakes cause significant psychological and physical trauma in children, especially when leading to amputations, as they disrupt physical, emotional, and social well-being.

Aim: This study was conducted phenomenologically to explore the experiences of children amputated in the Kahramanmaraş earthquake and their parents/caregivers.

Method: This study was conducted as a phenomenological study with children who were amputated in the Kahramanmaraş earthquake and their parents/caregivers between August and October 2023.

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Many factors such as religious beliefs, cultural structure, the perspective of the host country toward refugees, and the course of the migration process can affect the family planning and fertility behaviors of refugees. This study aimed to determine the knowledge, attitudes, and behaviors of Syrian refugee pregnant women in the Kayseri province of Türkiye regarding fertility characteristics and family planning. This descriptive and cross-sectional study was conducted with 290 pregnant Syrian refugee women.

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Carbon monoxide (CO) poisoning is a common occurrence, typically resulting from exposure to CO emissions in enclosed spaces. CO is a colorless, odorless, and tasteless gas. In this case report, we present a 52-year-old male patient who developed crush syndrome and acute kidney injury following carbon monoxide (CO) intoxication.

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  • Dual antiplatelet therapy (DAPT) is essential for managing acute and chronic coronary syndromes, helping to lower mortality rates and prevent further complications.
  • A study followed 1500 patients on a specific fixed-dose DAPT (ASA + clopidogrel) to evaluate its effectiveness and safety, primarily focusing on hospitalization and bleeding risks.
  • Results indicated that the fixed-dose combination therapy was effective, with low rates of hospitalization for cardiovascular issues and minimal bleeding complications in appropriately selected patients.
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Objective: We aimed to determine the role of plasma alpha- and beta-synuclein levels and other routine inflammatory parameters in the diagnosis, outcome, and mortality of acute ischemic stroke (AIS).

Methods: In our study, serum alpha- and beta-synuclein levels and clinical data were prospectively evaluated in 93 subjects (43 controls and 50 AIS patients) admitted to the emergency department. The outcome status and prognostic classification were performed according to the modified Rankin Scale (mRS) scores on the 30 day from hospital admission.

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Background: Since nursing students' interactions with nurses in the clinical practice process play an important role in nursing education and practice, it is a necessity to evaluate nurses' attitudes towards students.

Aim: To develop a valid and reliable measurement tool to determine the attitudes of nurses' towards nursing students in the clinical practice process.

Design: This study used a quantitative cross-sectional design.

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Introduction: Vasospasm has been reported as the most important cause of mortality and morbidity in patients with subarachnoid haemorrhage (SAH) who can reach the hospital. Matrix metalloproteinases (MMPs) are a gene family, which are called neutral proteases in the central nervous system (CNS). In this experimental study we studied the upregulation of MMPs (MMP-8, MMP-9, and MMP-13) gene expression and the inhibitor effects of doxycycline after experimental SAH model in rats.

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BCR::ABL1-negative myeloproliferative neoplasms (MPNs) pose a substantial risk of thrombosis, leading to significant morbidity and mortality. Anticoagulant therapy, historically based on vitamin K antagonists (VKAs), has limitations in preventing recurrent thrombotic events and managing bleeding complications. Direct oral anticoagulants (DOACs) offer a potential alternative with improved pharmacokinetics and compliance.

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Objective: Mechanisms of sleep disorders in fibromyalgia (FM) patients, such as insomnia, early morning awakenings and poor quality sleep, have not yet been proven and no consistent and effective treatment is yet available. The aim of this study was to investigate the pineal gland volume and the relationship between total fibre count, total fibre volume and total fibre length of the spinoreticular tract involved in regulation of sleep and wakefulness in terms of the mechanism of sleep disturbance.

Methods: This study included only female cases, 31 with fibromyalgia and 31 controls.

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DOCK8 deficiency due to a deep intronic variant in two kindreds with hyper-IgE syndrome.

Clin Immunol

November 2024

Division of Immunology, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. Electronic address:

Article Synopsis
  • DOCK8 deficiency causes most cases of autosomal recessive hyper-immunoglobulin E syndrome (HIES) due to mutations that disrupt protein expression, but some patients show symptoms without identifiable mutations.
  • Researchers used Whole Exome Sequencing to discover a deep intronic DOCK8 variant in two patients that led to a significant alteration in protein structure and function.
  • The findings indicate that non-coding mutations play a crucial role in immunodeficiency disorders, suggesting the need for further investigation into these types of mutations in unexplained immune system issues.
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  • The cold pressor test (CPT) is used to assess autonomic functions by inducing sympathetic activation, leading to increased blood pressure and heart rate in healthy individuals.
  • A study involving 40 healthy volunteers measured internal jugular vein (IJV) flow parameters before and after immersing their hands in cold water (1°C) for one minute.
  • Results showed significant increases in blood pressure, heart rate, and IJV volumetric flow, but a decrease in IJV diameter, indicating that CPT activates the sympathetic nervous system and affects venous flow in the IJV.
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Purpose: The C-reactive protein (CRP) velocity (CRPv) is an indicator of the change in CRP over time. In individuals with sepsis, the second values of CRP and CRPv have been shown to have more importance than the first CRP value measured at admission. This study examined the importance of CRPv for mortality among individuals who were hospitalized in the intensive care unit (ICU).

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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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  • Acute ischemic stroke (AIS) is a serious complication in COVID-19 patients, with a study showing it occurred in 2.31% of hospitalized patients, primarily affecting older individuals with existing health issues.
  • The study analyzed 693 COVID-19 patients from April 2020 to February 2021, revealing that many AIS cases arose within the first 24 hours, led by total anterior circulation infarction and cardioembolic causes.
  • Patients with AIS had a higher prevalence of hypertension and heart disease, with a significant mortality rate, highlighting the need for awareness and monitoring for stroke risks in COVID-19 cases, particularly in older adults.
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  • - The study assessed trauma CT interpretation proficiency among emergency medicine residents in Turkey, finding a median accuracy rate of 64.9% with factors influencing interpretation performance analyzed.
  • - Four main factors linked to interpretation failure were identified: shorter interpretation times, lower self-confidence, over-reliance on radiology reports, and lack of departmental training programs.
  • - The findings suggest the necessity for improved educational strategies in radiology for emergency medicine residents to enhance their skills in trauma CT interpretation and ultimately improve patient care outcomes.
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Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy that occurs when the median nerve is compressed within the carpal tunnel. Electromyography (EMG) is accepted as the most frequently used and important diagnostic method for CTS. Recently, magnetic resonance imaging (MRI) has begun to be used in CTS patients to directly visualize the median nerve and examine the changes occurring in the nerve structure.

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Evaluation of contraception methods in chronic myeloid leukemia patients: A Turkish multicenter study.

J Oncol Pharm Pract

September 2024

Division of Haematology, Department of Internal Medicine, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, Istanbul, Turkey.

Background And Aim: Chronic myeloid leukemia (CML) incidence has recently increased in younger individuals. With time, given the nature of the disease and available therapies, as well as the existing paucity and inconsistency of advice, worries about fertility have surfaced. With all these clear unknowns, we designed this study to raise awareness among both physicians and CML patients about whether male and female patients of childbearing age were using contraception at the time of diagnosis, and if so, which methods they were using.

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Leiomyomas and schwannomas are both types of rare benign soft tissue tumours. Leiomyomas are more commonly found in the lower limbs than in the upper extremities, while schwannomas are rare peripheral nerve sheath tumours that can occur in different anatomical regions. However, they rarely occur in the saphenous nerve.

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In March 2024, 12 European Network of Young Gynae Oncologists- (ENYGO-IJGC) Editorial Fellows conducted 10 interviews with senior opinion leaders on original and controversial topics in the field of gynecologic oncology presented during the 25th European Society of Gynaecological Oncology (ESGO) Congress in Barcelona, Spain. This article provides a summary and overview of the content of these discussions summarizing key points presented at the meeting. These selected interviews were chosen by consensus by the ENYGO-IJGC Editorial Fellows based on novelty and relevance to the field of gynecologic oncology.

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Purpose: This study aimed to assess the diagnostic accuracy of smartphone photographs, taken at the emergency department (ED) and shared with hand surgeons, in identifying critical circulatory issues and neurovascular bundle injury, as well as tendon and bone injuries.

Methods: The photographs of hand injuries of 50 patients who were referred to our ED between January 2020 and January 2022 were used to design a questionnaire. This questionnaire, including closed-ended questions about the injured structures, was shared with a group of hand surgeons via a WhatsApp group in Turkey.

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Article Synopsis
  • Spinal surgeries have become more common, especially for treating low back pain, which many people experience at some point in their lives.
  • Epidural fibrosis is a type of scar tissue that can form after spinal surgery, and researchers want to find better ways to prevent it.
  • In a study with rats, scientists tested two drugs, tenoxicam and diclofenac sodium, and found that they help stop the scar tissue from forming by blocking certain chemicals that cause inflammation.
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