386 results match your criteria: "Katip Çelebi University Atatürk Education and Research Hospital[Affiliation]"

Background: The two strongest earthquakes in Turkey for eight decades hit Kahramanmaraş province on February 6, 2023. This study aimed to determine psychiatric complaints, acute stress symptoms, anxiety, depression, and sleep characteristics in children who were treated in a tertiary inpatient pediatric unit after the earthquakes. They were evaluated in the fourth week after the earthquake.

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Aim: Breast cancer is the most common cancer in women and is a leading cause of cancer-related mortality. The role of neoadjuvant therapy (NAT) in conjunction with surgical intervention is becoming increasingly prominent in the field of oncology. NAT enhance the probability of breast-conserving surgery in cases of locally advanced breast cancer and in patients with metastatic or inoperable disease.

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Unlabelled: Allan-Herndon-Dudley syndrome is a neurodevelopmental disorder characterized by motor and intellectual disabilities. Despite its rarity, there has been a rise in interest due to ongoing research and emerging therapy suggestions. In this multicenter, retrospective, cross-sectional study, the genetic characteristics and clinical data of twenty-one cases of genetically confirmed MCT8 deficiency were evaluated.

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Background: The ultimate goal of asthma management is to have complete control of the condition, yet the number of patients with uncontrolled asthma continues to rise. This study aims to determine the prevalence of uncontrolled asthma, identify predictive parameters, and compare MART and non-MART treatment regimes.

Methods: A prospective questionnaire was administered to 495 patients who signed the consent form.

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Before and After Covid-19: What Has Changed in HIV Knowledge Level?

J Multidiscip Healthc

November 2024

Katip Celebi University, Ataturk Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Izmir, Turkey.

Introduction: The most essential way to prevent the transmission of Human Immunodeficiency Virus (HIV), one of the most important communicable diseases, is to enhance public knowledge. Our study aimed to assess whether there were any changes in HIV knowledge following the onset of the Covid-19 pandemic.

Methods: In Turkey, information stands were established in Izmir on 1 December 2017 and in public locations in both Istanbul and Izmir on 1 December 2021 to providing education the public about HIV/AIDS.

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Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) often leads to hospital readmissions, with a study involving 415 patients in Turkey revealing significant readmission rates of 42.4% within 30 days and 46% within 90 days after severe exacerbations.
  • Key risk factors for 30-day readmissions include high anxiety and depression scores, a history of severe exacerbations, hospital-acquired pneumonia, and frequent antibiotic use.
  • For 90-day readmissions, factors such as severe heart regurgitation, multiple moderate exacerbations, immunosuppression, and being hospitalized via the emergency department were significant contributors.
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  • COPD exacerbations can lead to increased morbidity and mortality, with prolonged hospital stays linked to various risk factors despite optimal care.
  • A study analyzed 434 COPD patients to identify factors influencing hospital length of stay (LOS), categorizing them into patient-related, disease-related, treatment-related, and hospital utility-related.
  • Key findings indicated that factors like biomass exposure, previous non-invasive mechanical ventilation, low bicarbonate levels, and increased oxygen needs were associated with difficult-to-manage exacerbations and longer hospitalizations.
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Acute pancreatitis (AP) is a clinical condition that arises acutely in the pancreas through various inflammatory pathways due to multiple causes. Turkish Society of Gastroenterology Pancreas Working Group developed comprehensive guidance statements regarding the management of AP that include its epidemiology, etiology, clinical presentation, diagnostic criteria, disease severity, treatment, prognosis, local and systemic complications. The statements were developed through literature review, deliberation, and consensus opinion.

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Resting state functional connectivity in adolescents with substance use disorder and their unaffected siblings.

Psychiatry Res Neuroimaging

December 2024

Department of Psychiatry, Ataturk Education and Research Hospital, Katip Celebi University, Izmir, Turkey. Electronic address:

Article Synopsis
  • The study investigates resting-state functional connectivity (rsFC) in adolescents with substance use disorder (SUD), their unaffected siblings, and typically-developing controls to find network organization changes linked to familial SUD risk.
  • Adolescents with SUD exhibited both weaker and stronger rsFC, specifically in the default-mode network (DMN) and its connections with other networks, compared to typically-developing controls.
  • Although unaffected siblings showed no overall differences from controls, they did present lower rsFC within the DMN and between the visual network and other networks, along with higher rsFC between the DMN and fronto-parietal network, indicating potential familial predispositions for SUD.
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Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions and repetitive behaviors. This study examines the effects of fenofibrate on a propionic acid (PPA)-induced rat model of ASD, focusing on behavioral changes, inflammatory markers, and histological findings.

Materials And Methods: Thirty male Wistar rats were divided into three groups: a control group, a group receiving PPA and saline, and a group treated with PPA and fenofibrate for 15 days.

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Objectives: To re-evaluate cut-offs for disease activity states according to the Axial Spondyloarthritis Disease Activity Score (ASDAS), and study the impact of sex, age, calendar time, disease and symptom duration on ASDAS and ASDAS cut-offs in a large contemporary cohort.

Methods: Data from 2939 patients with axial spondyloarthritis (axSpA) starting their first tumour necrosis factor inhibitor in nine European registries were pooled and analysed. Receiver operating characteristic analyses were performed to identify cut-offs against external criteria.

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Functional brain networks in clinical high-risk for bipolar disorder and psychosis.

Psychiatry Res

December 2024

Department of Neurosciences, Institute of Health Sciences, Dokuz Eylul University, Izmir, Turkey; Department of Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey; Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Victoria, Australia.

Abnormal connectivity in the brain has been linked to the pathophysiology of severe mental illnesses, including bipolar disorder and schizophrenia. The current study aimed to investigate large-scale functional networks and global network metrics in clinical high-risk for bipolardisorder (CHR-BD, n = 25), clinical high-risk for psychosis (CHR-P, n = 30), and healthy controls (HCs, n = 19). Help-seeking youth at CHR-BD and CHR-P were recruited from the early intervention program at Dokuz Eylul University, Izmir, Turkey.

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Article Synopsis
  • * The study reviewed 19 patients, predominantly experiencing hypoglycemia, with tumor locations identified in 74% of cases via CT and 88% via intraoperative ultrasound, and the most common surgical procedure was enucleation (53%).
  • * The findings suggest that accurately locating insulinomas is vital for the right surgical approach, with enucleation recommended for suitable patients due to its higher success rates and lower serious morbidity, despite a higher occurrence of pancreatic fistulas.
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  • Cerebral small vessel disease (SVD) can lead to various cerebrovascular issues, but research on sex differences in SVD is limited.
  • This study analyzed data from over 20,000 patients with acute ischemic stroke to examine whether the presence and severity of cerebral microbleeds (CMB) and other SVD markers differ between males and females.
  • Results showed that males had more frequent CMB while females had fewer lacunes but higher severe white matter hyperintensities, indicating distinct SVD characteristics based on sex.
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Objectives: We aimed to report the characteristics of pediatric IgG4-related disease (IgG4-RD) through a multicentre registry, to assess disease clusters, and to evaluate the performances of the 2019 American College of Rheumatology and European League Against Rheumatism (ACR/EULAR) classification criteria and the 2020 revised comprehensive diagnostic (RCD) criteria in this cohort.

Methods: Data of IgG4-RD patients in 13 pediatric rheumatology centers were recorded to a web-based registration system. The diagnosis of IgG4-RD was made according to the 2011 comprehensive diagnostic criteria.

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(1) Background: Unruptured Intracranial Aneurysms (UIAs) are common blood vessel malformations, occurring in up to 3 % of healthy adults. Magnetic Resonance Angiography (MRA) is frequently used for the screening of UIAs due to its high resolution in vascular anatomy. However, T2-Weighted Magnetic Resonance Imaging (T2WI) is a standard sequence utilized for the majority of outpatient head scans.

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Objectives: This study aims to compare the elastographic properties of the ovaries of patients with poor ovarian response (POR) with healthy controls by using real-time ultrasound tissue elastography and to investigate the predictive value of ovarian strain ratio (OSR) in the diagnosis of POR.

Materials And Methods: A cross-sectional study was conducted among infertility patients. OSR measurements of 46 women diagnosed with POR and 41 healthy controls with male infertility were performed by real-time ultrasound tissue elastography.

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Background: Endotracheal suctioning is a procedure used by neonatal intensive care unit nurses to maximize oxygenation and clear airways of secretions, and is one of the most common painful procedures causing stress in intubated newborns.

Aim: This aim of this study is to compare the effects of open and closed endotracheal suctioning on pain, peak heart rate and oxygen saturation in neonates on mechanicalventilation.

Materials And Methods: This experimental-design study was conducted on 30 newborns who were mechanically ventilated in the tertiary neonatal intensive care unit of a public hospital.

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Background: Diabetes foot infection is a very important public health problem that causes serious health problems, mortality, and high health expenditures, and is one of the most important complications of diabetes mellitus. There are concerns that approaches such as limited personal visits to doctors, avoidance of hospitals, and restrictions on nonemergency surgical procedures during the coronavirus disease of 2019 pandemic pose a threat to those with diabetic foot problems, including diabetic foot ulcers (DFUs), ischemia, and infection, resulting in increased limb loss and mortality.

Methods: This multicenter, retrospective, cross-sectional study was conducted in 14 tertiary care hospitals from various regions of Turkey.

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Spinal bone lesions encompass a wide array of pathologies, spanning from benign abnormalities to aggressive malignancies, such as diffusely localized metastases. Early detection and accurate differentiation of the underlying diseases is crucial for every patient's clinical treatment and outcome, with radiological imaging being a core element in the diagnostic pathway. Across numerous pathologies and imaging techniques, deep learning (DL) models are progressively considered a valuable resource in the clinical setting.

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Left Ventricular Hypertrophy Findings on Electrocardiogram Predict Impaired Left Atrial Functions.

Turk Kardiyol Dern Ars

July 2024

Department of Cardiology, Faculty of Medicine, Atatürk Research and Training Hospital, Katip Çelebi University, Izmir, Türkiye.

Objective: Electrocardiographic left ventricular hypertrophy (ECG LVH) holds significant clinical importance in cardiovascular disease. Pathological processes that lead to left ventricular hypertrophy (LVH) also induce remodeling and impair left atrial (LA) function. Atrial function can be assessed using speckle-tracking echocardiography.

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A scoping review of pain resulting from the endotracheal suctioning of paediatric intensive care patients.

Int J Palliat Nurs

June 2024

Information and Document Management, İzmir Kâtip Çelebi University, Faculty of Social Sciences and Humanities, İzmir, Turkey.

Background: This scoping review was conducted to summarise and map studies on pain resulting from endotracheal suctioning in paediatric intensive care patients.

Method: This scoping review conducted in June 2022 was performed by screening articles published in English. Scopus, PubMed, Cochrane, Web of Science, MedLine and Ovid databases were used for screening.

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Article Synopsis
  • Anastomotic stricture (AS) is a common complication after esophageal atresia (EA) repair, and a study was conducted using data from the Turkish Esophageal Atresia Registry to identify risk factors for its development.
  • The research included 713 patients from 2015 to 2021, finding that 20.19% developed AS, with significant factors like being a term baby, having a birth weight over 2,500g, experiencing gastroesophageal reflux (GER), and having a recurrent tracheoesophageal fistula (TEF).
  • The study concluded that these risk factors are critical for understanding AS development in EA patients, particularly within their first year of life, and emphasized the importance of
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Purpose: Spinal surgery is associated with severe diffuse pain in the postoperative period. Effective pain management plays an essential role in reducing morbidity and mortality. This study is designed to compare the ultrasound-guided erector spinae plane (ESP) block and surgical infiltrative ESP block for postoperative analgesia management after lumbar spinal fusion surgery.

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