408 results match your criteria: "Kasturba Medical College-Manipal[Affiliation]"

Importance of interprofessional collaboration in teaching diabetic foot self-management: Perceptions of health care professionals.

Med J Armed Forces India

December 2024

Professor (Physiotherapy) & Principal, KM Patel Institute of Physiotherapy, Pramukhswami Medical College Campus, Bhaikaka University, Karamsad, Gujarat, India.

Background: Diabetes and associated diabetic foot ulcers require coordinated management, including several health care professional (HCPs). Therefore, an interprofessional (IP) team-based approach is essential for effectively managing and educating the population on diabetic foot self-management strategies. However, the perceptions of the HCPs related to the importance of IP teamwork in diabetic foot care and their readiness to work in an IP team are less explored.

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ABO-incompatible transplantations are increasingly gaining relevance with advancements in therapeutic modalities, thus allowing patients to receive timely solid organ transplants. Therapeutic apheresis (TA) procedures remain instrumental as a preconditioning measure to enable such transplants. This survey was undertaken to find out current trends and practices of TA across major transplant centers in India.

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A man in his early 60s presented with dysphagia and odynophagia. He was diagnosed with squamous cell carcinoma of the oesophagus. During his hospital stay, he developed a productive cough and experienced recurrent fever spikes.

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Purpose: To investigate the current thoughts and perspectives on kidney stone analysis amongst urologists and urology residents worldwide.

Methods: In October 2022 an online survey supported by the EULIS was circulated amongst urologists and urology residents worldwide. The survey was based on the current EAU guidelines regarding stone analysis and its role in urolithiasis management.

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Objectives: The prevalence and burden of neurological diseases are high among the older age group. Stroke and other neurological diseases significantly impair functional capacity and lead to poor quality of life. This study aims to provide a national-level estimate for palliative and supportive care needs among older Indian adults with stroke and other neurological diseases.

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An Observational Study on Female Genital Dermatoses and the Impact of Chronic Genital Dermatoses on Quality of Life in Adult Females.

Indian J Dermatol

October 2024

From the Department of Dermatology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Background: Female genital dermatoses (FGD) or vulvar dermatoses are a group of disorders that affect the vulva and contiguous parts. Most of the FGDs can be chronic or recurrent. Effects on Quality of life (QoL) in patients having dermatological conditions are well studied but this is not the case in vulvar dermatoses.

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Article Synopsis
  • Exercise training is increasingly recognized as a valuable addition to medical treatment for pulmonary arterial hypertension (PAH), but the metabolic changes it induces are not well understood.
  • The study involved male Wistar rats, which were divided into four groups, with some undergoing treadmill exercise for five weeks to analyze metabolic effects.
  • Results indicated significant alterations in lipid and amino acid metabolism due to PAH, but exercise helped restore normal levels of arginine and homocysteine, potentially improving PAH outcomes.
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Background: One in five people will be older than 60 by the year 2050 in India. This demographic transition demands integration of geriatric and palliative care. The national level burden of palliative and supportive care needs of the older population is largely unknown in India.

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Article Synopsis
  • Treating chronic bone illnesses can be very expensive, prompting a study to compare the costs of Jan Aushadhi (JA) medicines with both the cheapest and most expensive branded options in India.
  • The analysis examined 67 medications for various conditions, revealing that JA drugs are significantly cheaper; for example, some branded medications were over 32 times more expensive than JA alternatives.
  • The findings highlight the substantial cost savings possible by opting for JA medicines, making them a viable alternative for patients seeking affordable treatment for bone-related issues.
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Background: Facial emotion recognition (FER) deficits are being considered as core features of social cognitive deficits in schizophrenia, associated with socio-occupational dysfunction. Social cognition intervention programs have been shown to improve these deficits; however, there are no such intervention strategies in India. In this study, we aim to examine the efficacy of Training of Affect Recognition - Indian Version (TAR-IV) to enhance the FER abilities of people with schizophrenia.

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Background: Exposure to complex trauma in early childhood can undermine the development of mentalization capacity. Complex trauma has also been causally linked to borderline personality disorder (BPD). The inclusion of complex post-traumatic stress disorder in ICD-11 has made it imperative to have an in-depth understanding of complex trauma.

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An Algorithm for Management of Radial Longitudinal Deficiency.

J Hand Surg Asian Pac Vol

December 2024

Department of Hand Surgery, Kasturba Medical College Manipal, Manipal Academy Of Higher Education, Manipal, Karnataka, India.

Article Synopsis
  • - The management of radial longitudinal deficiency (RLD) lacks specific guidelines, resulting in varied treatment approaches that complicate the determination of effective interventions for individual patients.
  • - Approximately 40% of RLD cases are associated with syndromes like Holt-Oram, TAR, and VACTERL, making it essential for hand surgeons to recognize these conditions and their implications for treatment.
  • - Surgical procedures like centralisation and radialisation are fundamental for treatment, but current methods do not fully restore normal wrist function; emerging techniques focus on improving biomechanics and considering proximal limb changes in management.
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The solid variant of aneurysmal bone cyst is an expansile cystic lesion involving long tubular bones with unknown aetiology and usually occurs in the second decade of life. This is a paradigm of fibrocystic lesions. We report the rare case of a male with a biopsy-proven solid variant aneurysmal bone cyst of the cuboid that was mistakenly diagnosed as osteomyelitis.

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Lipomas of the talus are rare benign bone lesions. They are usually atraumatic in aetiology with a male preponderance and generally occur between the third and sixth decades of life. We report the case of a man in his 30s who had presented with pain and swelling in the posteromedial aspect of his left ankle of 6 months' duration, associated with functional restrictions, and was diagnosed as a case of intraosseous lipoma involving the talus.

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Mycetoma of the hand is a chronic granulomatous disease seen in the tropics and subtropical regions, mainly affecting the skin and subcutaneous tissue of the foot. Primary actinomycotic osteomyelitis involving the metacarpals is rarely reported in the literature. The conventional treatment for actinomycosis has been high-dose penicillin.

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Neurofilaments are intermediate filaments present in neurons. These provide structural support and maintain the size and shape of the neurons. Dysregulation, mutation, and aggregation of neurofilaments raise the levels of these proteins in the blood and cerebrospinal fluid (CSF), which are characteristic features of axonal damage and certain rare neurological diseases, such as Giant Axonal Neuropathy and Charcot-Mare-Tooth disease.

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Objective: To identify a suitable approach for blood irradiation other than the commonly used water medium and to study the impact of different algorithm dose computations.

Methods: Water is the commonly used medium for blood irradiation. In this study computed tomography scans were taken with locally made blood irradiation phantoms other than water, by using air, rice powder and thermocole using parallel beam for 25 Gy.

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Article Synopsis
  • Chloride levels, often overlooked in critically ill patients, can indicate serious outcomes, such as acute kidney injury (AKI) and major adverse kidney events (MAKE30) in those with sepsis.
  • In a study involving 400 sepsis patients, hypochloremia was found to be a significant risk factor for adverse kidney outcomes, with 32.3% of patients showing low chloride levels within 72 hours of ICU admission.
  • Conversely, hyperchloremia did not demonstrate any significant association with MAKE30 or worsening AKI, suggesting that low chloride levels are more critical to monitor in sepsis patients.
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Photobiomodulation therapy for mitigating severity of radiodermatitis in cancer patients undergoing radiotherapy: a scoping review.

Support Care Cancer

October 2024

Photoceutics and Regeneration Laboratory, Centre for Microfluidics, Biomarkers, Photoceutics and Sensors (μBioPS), Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.

Purpose: Radiodermatitis (RD) is an adverse effect of radiation therapy. RD can negatively impact quality of life and can also hinder treatment in cancer patients. Photobiomodulation therapy (PBMT) has the potential to treat RD at the cellular level, and it is more promising compared to other therapy alternatives.

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Multicentric Osteolysis Nodulosis and Arthropathy (MONA) is a rare skeletal disorder driven by mutations in the MMP2 gene, leading to bone and joint degradation. This case series presents three unique MONA cases, highlighting clinical, radiological, and genetic aspects. These insights shed light on the complexities of MONA, aiding early diagnosis and multidisciplinary management.

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LGBTQ+ people (e.g., lesbian, gay, bisexual, transgender, and queer or questioning people) experience systemic marginalisation and discrimination globally and throughout India.

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Study Design: Prospective single-center study.

Purpose: To compare the accuracy of pedicle screws placed by freehand and under fluoroscopy and robotic assistance with intraoperative image acquisition.

Overview Of Literature: Pedicle screws are the most commonly used spinal anchors owing to their ability to stabilize all three spinal columns.

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Uncommon and Unusual Variants of Autoimmune Bullous Diseases.

Indian Dermatol Online J

August 2024

Department of Dermatology, Venereology and Leprology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Article Synopsis
  • Autoimmune blistering diseases (AIBDs) are skin conditions caused by the body's immune system attacking certain proteins, leading to blister formation, and can be categorized into intraepidermal and subepidermal types.
  • The objective of this review is to raise awareness about rare and uncommon AIBD variants, such as pemphigus herpetiformis and anti-laminin 332 pemphigoid, among others.
  • By discussing these unusual variants, the review aims to assist healthcare professionals in the early diagnosis and treatment of these conditions.
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