Evaluation of TNF-α and IFN-γ primed conditioned medium of mesenchymal stem cell in acetic acid-induced mouse model of acute colitis.

IBD, an autoimmune-inflammatory disorder that affects people who are genetically prone to inflammation. There is a lot of interest in MSC-CM therapy, especially when primed with TNF-α + IFN-γ. Throughout the study, data were collected on the percentage of apoptotic cells, gene expression of ZO-1, Foxp3, GATA3, IDO-1, Muc2, T-bet, Notch1, TNFR2, and ROR-γt, colon weight and length, histopathological analysis, and DAI.

Prediction of breath-holding spells based on electrocardiographic parameters using machine-learning model.

Background: Breath-holding spells (BHS) are common in infancy and early childhood and may appear like seizures. Factors such as autonomic dysfunction and iron deficiency anemia are thought to contribute to the incidence of BHS. In this study, electrocardiographic (ECG) parameters of patients with BHS were compared to those of healthy, normal children.

The Impact of Loving-Kindness Meditation on Compassion Fatigue of Nurses Working in the Neonatal Intensive Care Unit: A Randomized Clinical Trial Study.

Compassion fatigue is a common complication in nurses, which can lead to burnout, job dissatisfaction, and a decline in the quality of patient care. This study aimed to investigate the impact of loving-kindness meditation on compassion fatigue of nurses working in the neonatal intensive care unit (NICU). This cluster-blinded randomized clinical trial study was conducted on 66 NICU nurses in 2 educational hospitals selected.

Paroxysmal dyskinesia and electrodermal volatility: The role of mindfulness, self-compassion and psychophysiological interventions.

To date, there are no behavioral or psychophysiological treatment studies on paroxysmal dyskinesia (PD). PD is a group of debilitating movement disorders that present with severe episodes of dystonia, chorea, and/or ballistic like movements. This is a first case report of a 50-year-old male who received behavioral interventions (e.

MDA Framework for FAIR Principles.

This paper shows that the MDA framework can be helpful for designing and implementing FAIR principles. We reached this conclusion based on a focus group interview with six experts, during which we focused on the three MDA components: mechanics, dynamics and aesthetics.

Mobile-Based Self-Care Application for COVID-19: Development Process Using the ADDIE Model.

During the COVID-19 era, technology-enhanced protection of this disease has saved lives in developed countries in which citizens have the privilege of accessing and using such technologies to fight Coronavirus. In the undeveloped countries, on the other hand, citizens have had no accession or ability to use digital technologies to prevent COVID-19. Having this in front, in the MyShield research project, we aim to address how to teach self-care skills in undeveloped countries in the era of COVID-19 using a mobile low-cost application effectively based on a standard educational model (ADDIE).

The effect of Cornus mas extract consumption on bone biomarkers and inflammation in postmenopausal women: A randomized clinical trial.

The drastic decrease in estrogen levels in menopausal women can elevate bone resorption and osteoporosis. Cornus mas extract (C. mas extract) is a potential candidate for treating menopausal-related bone complications because of its phytoestrogen and anti-inflammatory contents.

Clinical and Epidemiological Characteristics of Postdischarge Patients With COVID-19 in Tehran, Iran: Protocol for a Prospective Cohort Study (Tele-COVID-19 Study).

Background: COVID-19 was declared a pandemic on March 11, 2020. Given that the severe shortage of hospital beds has led to early discharge and insufficient patient education on home care routines and isolation protocols, the close follow-up of patients and their immediate relatives is an integral part of transitioning from hospital care to home care for patients with COVID-19.

Objective: We designed the Tele-COVID-19 prospective cohort to follow-up with COVID-19 patients in Tehran, Iran, and improve health care delivery and the recording of postdischarge patients' clinical profiles.

Nursing process education: A review of methods and characteristics.

The concepts of the nursing process have been assigned as important plans for the curricula and continuing education programs in the nursing discipline. This paper focuses on the main characteristics of the educational methods applied in training programs in the nursing process or nursing care plan. The original studies were extracted from the PubMed, ProQuest, Scopus, Science Direct and, Web of Science databases, following two-step screening by two reviewers.

An Expert System to Diagnose Pneumonia Using Fuzzy Logic.

Introduction: Pneumonia is the most common and widespread killing disease of respiratory system which is difficult to diagnose due to identical clinical signs of respiratory system.

Aim: In this research, to diagnose this, a structure of a fuzzy expert system has been offered. This is done in order to help general physicians and the patients make decision and also differentiate among chronic bronchitis, tuberculosis, asthma, embolism, lung cancer.

Intelligent Computer Systems for Multiple Sclerosis Diagnosis: a Systematic Review of Reasoning Techniques and Methods.

Objective: Intelligent computer systems are used in diagnosing Multiple Sclerosis and help physicians in the accurate and timely diagnosis of the disease. This study focuses on a review of different reasoning techniques and methods used in intelligent systems to diagnose MS and analyze the application and efficiency of different reasoning methods in order to find the most efficient and applicable methods and techniques for MS diagnosis.

Methods: A complete research was carried out on articles in various electronic databases based on Mesh vocabulary.

Clinical and Para Clinical Information Needs of Infertility Electronic Health Records in Iran: A Delphi Study.

Background: infertility is referred to the person's inability to conceive pregnancy after one year of intercourse without using protection. This study paves the ground for creating a complete, united, and coherent source of patients' medical information.

Materials And Methods: this is an applied research of descriptive-cross sectional type which has been carried out through qualitative - quantitative methods.

A Retrospective Study on Scropionism in Iran (2002-2011).

Background: Scorpion sting is a common medical emergency in Iran. The epidemiological features and control of such cases vary from south to north. This review will provide new information about the epidemiology of scorpion stings in different provinces of Iran.

Barriers and Facilitators to Implementing a Change Initiative in Long-Term Care Using the INTERACT® Quality Improvement Program.

Implementation of major organizational change initiatives presents a challenge for long-term care leadership. Implementation of the INTERACT® (Interventions to Reduce Acute Care Transfers) quality improvement program, designed to improve the management of acute changes in condition and reduce unnecessary emergency department visits and hospitalizations of nursing home residents, serves as an example to illustrate the facilitators and barriers to major change in long-term care. As part of a larger study of the impact of INTERACT® on rates of emergency department visits and hospitalizations, staff of 71 nursing homes were called monthly to follow-up on their progress and discuss successful facilitating strategies and any challenges and barriers they encountered during the yearlong implementation period.

Status of ocular trauma in hospitalized patients in Kashan, 2011: As a sample of industrial city.

Purpose: Ocular trauma is the third leading cause of hospitalization in ophthalmology patients, imposing direct and indirect physical and psychological costs on society. This study aims to investigate the status of ocular trauma in hospitalized patients in the industrialized city of Kashan in 2011.

Methods: This cross-sectional descriptive applied study was conducted in 2012 on patients hospitalized for ocular trauma.

Older Adults of Underrepresented Populations and Their End-of-Life Preferences: An Integrative Review.

This integrative review was conducted to examine the evidence for understanding diversity in end-of-life preferences among older adults of underrepresented groups. Findings from 21 studies were critically examined, grouped, and compared across studies, populations, and settings. Five major themes emerged: advance directives, hospice and palliative care, communication, knowledge and information, and home and family.

Quality of sleep and its related risk factors in hospitalized older patients in Kashan's Hospitals, Iran 2009.

Context: Sleep is an effective factor in the process recovery from diseases. Many variables affect the sleep quality of hospitalized older patients.

Aim: This study was conducted to evaluate the quality of sleep and its related risk factors in hospitalized older patients in Kashan's hospitals, Iran 2009.

Gastrointestinal parasites of stray cats in Kashan, Iran.

Considering the role of parasites in contamination of human beings and domestic animals and lack of information in the region, the present study was performed to investigate the infection status of helminthes and protozoa of stray cats in central Iran. A cross - sectional study was conducted on 113 stray cats trapped from different geographic regions of Kashan during four seasons and were necropsied. Different organs including: kidney, heart, liver, lungs, gastrointestinal tract and abdominal cavity were inspected for helminthes and protozoa infection.

Effects of a self-care program on quality of life of cirrhotic patients referring to Tehran Hepatitis Center.

Background: Chronic liver disease especially liver cirrhosis is one of the medical problems that substantially reduces the quality of life of its victims. Because of the chronic and irreversible nature of the disease, it needs self-care programs to be developed according to client's needs and to maintain their independence and sense of well-being. The purpose of this study was to determine the effects of a self-care educational program on Quality of Life (QoL) of a sample of Iranian cirrhotic patients.