8 results match your criteria: "Karolinska universitets-sjukhuset[Affiliation]"

[Not Available].

Lakartidningen

June 2024

docent, överläkare, VO infektionssjukdomar, Akademiska sjukhuset, Uppsala, Referensgruppen för antibiotikafrågor (RAF).

View Article and Find Full Text PDF

CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.

Stem Cell Reports

February 2022

Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland. Electronic address:

Conventional reprogramming methods rely on the ectopic expression of transcription factors to reprogram somatic cells into induced pluripotent stem cells (iPSCs). The forced expression of transcription factors may lead to off-target gene activation and heterogeneous reprogramming, resulting in the emergence of alternative cell types and aberrant iPSCs. Activation of endogenous pluripotency factors by CRISPR activation (CRISPRa) can reduce this heterogeneity.

View Article and Find Full Text PDF

Modern cancer therapy has noticeably improved the prognosis for various cancer diseases, but cardiovascular side effects are not uncommon, both in short and long term. The individual patient's cardiovascular risk profile affects the risk of developing side effects. Potential underestimation of this risk can lead to life-long severe cardiac disease for a patient that has been cured from cancer.

View Article and Find Full Text PDF

[Tight foreskin is usually a benign condition].

Lakartidningen

July 2013

Karolinska universitets-sjukhuset, institutionen för kvinnors och barns hälsa, Karolinska institutet, Stockholm.

View Article and Find Full Text PDF

Object: Intracranial chondrosarcomas have a high risk of recurrence after surgery. This retrospective study of patients with intracranial chondrosarcoma was conducted to determine the long-term results of microsurgery followed by Gamma Knife surgery (GKS) for residual tumor or recurrence.

Methods: The authors treated nine patients whose median age was 36 years.

View Article and Find Full Text PDF