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Using collective expert judgements to evaluate quality measures of mass spectrometry images.
Bioinformatics
June 2015
European Molecular Biology Laboratory, Heidelberg, Germany, Center for Industrial Mathematics, University of Bremen, Bremen, Germany, High Performance Humanoid Technologies Lab, Institute for Anthropomatics, Karlsruhe Institute of Technology, Karlsruhe, Germany, Denator, Uppsala, Sweden, Protim, Inserm U1085 - Irset, University of Rennes 1, Rennes, France, SCiLS GmbH, Bremen, Germany, College of Computer and Information Science, Northeastern University, Boston, MA, USA and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA European Molecular Biology Laboratory, Heidelberg, Germany, Center for Industrial Mathematics, University of Bremen, Bremen, Germany, High Performance Humanoid Technologies Lab, Institute for Anthropomatics, Karlsruhe Institute of Technology, Karlsruhe, Germany, Denator, Uppsala, Sweden, Protim, Inserm U1085 - Irset, University of Rennes 1, Rennes, France, SCiLS GmbH, Bremen, Germany, College of Computer and Information Science, Northeastern University, Boston, MA, USA and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA European Molecular Biology Laboratory, Heidelberg, Germany, Center for Industrial Mathematics, University of Bremen, Bremen, Germany, High Performance Humanoid Technologies Lab, Institute for Anthropomatics, Karlsruhe Institute of Technology, Karlsruhe, Germany, Denator, Uppsala, Sweden, Protim, Inserm U1085 - Irset, University of Rennes 1, Rennes, France, SCiLS GmbH, Bremen, Germany, College of Computer and Information Science, Northeastern University, Boston, MA, USA and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA European Molecular Biology Laboratory, Heidelberg, Germany, Center for Industrial Mathematics, University of Bremen, Bremen, Germany, High Performance Humanoid Technologies Lab, Institute for Anthropomatics, Karlsruhe Institute of Technolo
Motivation: Imaging mass spectrometry (IMS) is a maturating technique of molecular imaging. Confidence in the reproducible quality of IMS data is essential for its integration into routine use. However, the predominant method for assessing quality is visual examination, a time consuming, unstandardized and non-scalable approach.
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