Long-Term Effect of Half-Fluence Photodynamic Therapy on Fundus Autofluorescence in Acute Central Serous Chorioretinopathy.

Purpose: To evaluate normalized short-wavelength fundus autofluorescence (SW-FAF) imaging changes over time as a predictive parameter for the retinal pigment epithelium (RPE) function in eyes compromised by acute central serous chorioretinopathy (CSCR) after indocyanine green angiography-guided verteporfin (Visudyne®, Novartis Pharma, Basel, Switzerland) photodynamic therapy (PDT) with a half-fluence rate (25 J/cm).

Methods: Quantitative data of SW-FAF grey values (SW-FAF GV) from a 350 m (SW-350) and 1200 m (SW-350) and 1200 -test was calculated to explore the differences of SW-350 and SW-1200 between one month and the long-term follow-up.

Results: Mean differences (95% CI) in SW-FAF GV between 1 month and 7 years after half-fluence PDT were 0.