Enhancing yield and oil content in oilseed rape hybrids: Insights from line × tester and SIIG approaches.

Background: The production of high-oil-yielding hybrid varieties is a primary objective in oilseed rape ( L.) breeding programs. Biometric genetic experiments such as line × tester provide valuable insights into the genetic structure of traits associated with high oil yield.

The effect of quercetin on adipogenesis, lipolysis, and apoptosis in 3T3-L1 adipocytes: The role of SIRT1 pathways.

Background: Lipotoxicity, caused by adipocyte triglyceride over-accumulation, contributes to obesity-related comorbidities such as hypertension, type 2 diabetes, coronary heart disease, respiratory dysfunction, and osteoarthritis. This study focuses on determining how sirtuin-1 (SIRT-1) mediates quercetin's (QCT) effect on 3T3-L1 adipocytes. Key aspects of this study include preventing adipogenesis, inducing lipolysis, and stimulating adipocyte apoptosis.

Systematic review and meta-analysis of knowledge, attitudes, and practices regarding COVID-19 among chronic disease patients: A global perspective.

Background: Chronic health conditions were significantly correlated with an increased clinical severity of coronavirus 2019 (COVID-19) and a heightened risk of COVID-19 mortality. This study aims to determine global knowledge, attitudes, and practices (Knowledge Abuse Profile) of the patients with chronic diseases toward COVID-19.

Methods: The study was initiated in December 2019 and extended until April 2023, during which an extensive search for relevant English-language literature was conducted as part of this systematic review and meta-analysis.

Anti-Bacterial Activity of Four Distinct Propolis Extracts against and ; Etiological Agent of American and European Foulbrood Disease of Honeybees.

Four different propolis samples obtained from different regions of Iran were evaluated for their antibacterial effects against the bacterial agents responsible for two important honeybee diseases. () and (), as the etiological agents of American foulbrood (AFB) and European foulbrood (EFB) diseases, were subjected to propolis ethanolic extracts in the agar well diffusion assay. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the antibacterial effects of the samples against the two indicator organisms were determined by the microdilution technique using different concentrations of the propolis extracts.

An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent.

Drug resistance to antibacterial and anticancer drugs is one of the most important global problems in the treatment field that is constantly expanding and hinders the recovery and survival of patients. Therefore, it is necessary to identify compounds that have antibacterial and anticancer properties or increase the effectiveness of existing drugs. One of these approaches is using natural compounds that have few side effects and are effective.

NMDA Receptors in the Rat Paraventricular Thalamic Nucleus Reduce the Naloxone-induced Morphine Withdrawal.

Background: NMDA receptors have a significant role in the development of opioid physical dependence. Evidence demonstrated that a drug of abuse enhances neuronal excitability in the Paraventricular Nucleus (PVT). The current research studied whether blocking NMDA receptors through the administration of MK801 in the PVT nucleus could affect the development of Morphine (Mor) dependence and hence the behavioral indices induced by morphine withdrawal in rats.

Genotype and environment interaction and stability of grain yield and oil content of rapeseed cultivars.

Investigating the interaction of genotype and environment in multi-environment experiments (MET) is one of the reliable techniques to demonstrate the most stable and compatible cultivars. The main contribution of this study is to evaluate the stability and compatibility of rapeseed cultivars using additive main effects and multiplicative interaction (AMMI) and genotype plus genotype environment interaction (GGE) bi-plot methods for grain yield and oil content. For this purpose, an experiment in a randomized complete block design (RCBD) with three replications was conducted for 10 rapeseed cultivars across 10 environments (five regions in 2 years).

Administration of Orexin-A into the Rat Thalamic Paraventricular Nucleus Enhances the Naloxone Induced Morphine Withdrawal.

Objective: Orexin neuropeptides are implicated in physical dependence on opioids and expression of withdrawal symptoms in drug abuse. The paraventricular nucleus of the midline thalamus (PVT) has a high expression of orexin receptors. The current research studied the effect of orexin-A in the PVT area on the development of behavioral indices produced by morphine withdrawal in rats.

Genome-wide association study in diverse Iranian wheat germplasms detected several putative genomic regions associated with stem rust resistance.

Stem rust is one of the most important diseases, threatening global wheat production. Identifying genomic regions associated with resistance to stem rust at the seedling stage may contribute wheat breeders to introduce durably resistant varieties. Genome-wide association study (GWAS) approach was applied to detect stem rust () resistance genes/QTLs in a set of 282 Iranian bread wheat varieties and landraces.

Assessment of genotype-trait interaction in maize ( L.) hybrids using GGT biplot analysis.

In order to investigate the interaction of genotype × trait and relationships among agronomic traits on 12 maize hybrids, an experiment was conducted in a randomized complete block design (RCBD) with three replicates in four regions of Karaj, Birjand, Shiraz, and Arak. Results of analysis of variance indicated that most of the genotypes were significantly different in terms of agronomic traits. Mean comparison by Duncan's method showed that KSC705 genotype was more favorable than other genotypes in all studied regions.

A study on genotype-environment interaction based on GGE biplot graphical method in sunflower genotypes ( L.).

GGE biplot technique is one of the appropriate methods for investigating the genotype-environment interaction. An experiment was conducted to examine and evaluate the stability and adaptability of grain yield of 12 sunflower genotypes using the randomized complete block design (RCBD) with three replications in five regions including Karaj, Birjand, Firooz-Abad, Kashmar, and Arak within two agricultural years. Analysis of variance indicated that the effect of location, year, location × year, genotype, and genotype × location was significant at 1% probability level.

Simultaneous use of sensory stimulation and motor exercise improves the manual skills of educable children with mental retardation at preprimary and primary school levels.

Children with mental retardation have various clinical problems. They mostly have motor delay and sensory deficit. Neurorehabilitation focuses on restoring remaining abilities.

Metagenomic investigation of bacteria associated with dental lesions: a cross-sectional study.

Background: Dental caries is considered as one of the most significant global health problem over the world. Dental caries initiates from bacterial shifts within the supragingival biofilm, then a polymicrobial biofilm is formed on the surface of tooth, and finally various bacterial species aggregate in a complex-organized manner. The exploiting variability in 16S rRNA gene sequence has been considered as a cost-efficient high-throughput characterization approach in human oral microbiome investigations.

Comparing the attitude of doctors and nurses toward factor of collaborative relationships.

Background And Objectives: Effective relationship and collaboration between doctors and nurses is considered the main factor in achieving positive medical results, which is the most important goal of the healthcare system. This study aims to compare attitude of doctors and nurses toward factors associated with doctor-nurse collaboration, including shared education and teamwork, caring as opposed to curing, physician's dominance, and nurses' autonomy.

Methods: In this cross sectional, descriptive-comparative study, the Jefferson Scale of Attitudes toward Physician-Nurse Collaboration was used to assess doctor-nurse collaboration in four domains, including shared education and teamwork, caring as opposed to curing, physician's dominance, and nurses' autonomy.

The Prevalence of Personality Disorders among Emergency Nurses Based on MMPI-2 Questionnaire; a Cross-sectional Study.

Introduction: The prevalence of behavioral disorders is substantially higher in stressful working environments such as emergency departments. The present study aimed to evaluate the prevalence of personality disorders among emergency nurses.

Methods: In the present epidemiologic study, the prevalence of personality disorders among emergency nurses of three educational hospitals, Tehran, Iran, were evaluated based on Minnesota Multiphasic Personality Inventory-2 (MMPI-2) test.

Occupational risk assessment in the construction industry in Iran.

Occupational accidents in the construction industry are more common compared with other fields and these accidents are more severe compared with the global average in developing countries, especially in Iran. Studies which lead to the source of these accidents and suggest solutions for them are therefore valuable. In this study a combination of the failure mode and effects analysis method and fuzzy theory is used as a semi-qualitative-quantitative method for analyzing risks and failure modes.