Nursing department directors' perspectives on leadership training programme: A descriptive qualitative study.

Background: Leadership training is crucial for nurses to navigate changes, but research on nursing department directors' views of such programmes is limited.

Aim: To explore the perspectives and experiences of nursing department directors regarding a national leadership training programme for mid-level nurse managers.

Design: Descriptive Qualitative Study.

Distinct cross talk of IL-17 & TGF-β with the immature CD11c TRAF6 -null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo.

Background: Dendritic cells (DCs), though borne heterogeneous, are the most potent antigen-presenting cells, whose critical functions include triggering antigen-specific naïve T-cell responses and fine-tuning the innate versus adaptive immunity at the osteo-immune and/or mucosal mesenchyme interface. We previously reported that immature myeloid-CD11c DCs/mDCs may act like osteoclast (OC) precursors (OCp/mDDOCp) capable of developing into functional OCs via an alternative pathway of inflammation-induced osteoclastogenesis; however, what are their contribution and signaling interactions with key osteotropic cytokines (i.e.

Potential contribution of immature myeloid CD11cdendritic cells-derived osteoclast precursor to inflammation-induced bone loss in the TRAF6-null chimeras .

Dendritic cells (DC) are potent antigen-presenting-cells widely distributed at the osteo-immune and/or mucosal-mesenchyme interface, consequentially implicating in certain bone-sparing disorders; i.e., via signaling Receptor-activator-of-nuclear-factor-kappa-B-ligand/RANKL-Receptor-activator-of-nuclear-factor-kB/RANK-Osteoprotegerin/OPG-TRAF6 transducer-complex , evidently associated with arthritis, osteoporosis and periodontitis.