1,277 results match your criteria: "Kanuni Sultan Süleyman Research and Training Hospital; İstanbul[Affiliation]"

Severe pertussis infections in pediatric intensive care units: a multicenter study.

Eur J Pediatr

January 2025

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Unlabelled: This study aims to evaluate the clinical course of critical pertussis illness to the pediatric intensive care unit in Istanbul. The study was conducted as a multicenter, retrospective study between January 1, 2023, and December 31, 2023. Cases with positive polymerase chain reaction testing for Bordetella pertussis of nasopharyngeal swab samples within the first 24 h of pediatric intensive care unit admission were recorded.

View Article and Find Full Text PDF

The aim of this study is to determine the mediating role of moral sensitivity in the effect of nurses' professional values on missed nursing care. A descriptive and correlational study was conducted with 640 nurses working in the inpatient units of a public and a private hospital with the MISSCARE Survey-Turkish, the Moral Sensitivity Questionnaire, and the Revised Nursing Professional Values Scale. Data analyses were performed using the Statistical Package for Social Sciences 26.

View Article and Find Full Text PDF

Objectives: In this study, we retrospectively examined the bleeding that occurred in the 5-year patient series.

Materials And Methods: One thousand seven hundred seventy-five patients who underwent septorhinoplasty surgery between 2019 and 2023 were included in the study, and 28 of these patients who presented with bleeding complications were examined. All patients underwent open-technique septorhinoplasty surgery with or without concha intervention and were discharged the next day after overnight hospitalization.

View Article and Find Full Text PDF

Background: This study aimed to determine the mediating role of social intelligence in the effect of nurses' work-related strain on trait anger and anger expressions. The challenging working conditions for nurses often result in increased strain and anger. Social intelligence could help to manage anger.

View Article and Find Full Text PDF

This study was aimed to identify the most frequently observed pathogens in uncomplicated urinary tract infections from outpatient urinary isolates obtained across seven different geographical regions in Türkiye and to determine whether the antibiotic resistance rates of these pathogens differ significantly between these regions. The study included patients aged 18 to 65 years who were diagnosed with uncomplicated urinary tract infections and had positive urine cultures from March 2021 to August 2022, across 37 different centers in Türkiye. The participating centers were selected based on their use of the disk diffusion method, in line with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, to ensure standardization of urine culture data.

View Article and Find Full Text PDF

Objectives: An analytical protocol based on isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS), which includes a peptide-based calibration strategy, was developed and validated for the determination of cardiac troponin I (cTnI) levels in clinical samples. Additionally, the developed method was compared with a protein-based calibration strategy, using cTnI serving as a model for low-abundant proteins. The aim is to evaluate new approaches for protein quantification in complex matrices, supporting the metrology community in implementing new methods and developing fit-for-purpose SI- traceable peptide or protein primary calibrators.

View Article and Find Full Text PDF

Laparoscopic sleeve gastrectomy is a restrictive surgery that aims to decrease the gastric volume of the patient. This study hypothesized that a higher resected gastric volume to the number of fired staplers ratio is associated with improved postoperative 12th-month outcomes. To analyze the effects of resected gastric volume to the number of fired staplers ratio on postoperative results in patients who underwent sleeve gastrectomy.

View Article and Find Full Text PDF

Introduction: The severity of electrical injuries depends on the voltage, the duration of exposure to current, and the trajectory of the current through the body. The reconstruction for defects caused by electric current is a difficult process.

Objective: The purpose of this study is to investigate the effectiveness of the reverse first dorsal metatarsal artery (FDMA) flap in the reconstruction of distal foot injuries caused by electric currents.

View Article and Find Full Text PDF
Article Synopsis
  • Preseptal cellulitis is an inflammation of the eyelid and skin around the eye, often occurring in children after minor injuries.
  • While it usually has a good outlook, all orbital infections must be diagnosed and treated quickly to avoid serious complications.
  • Proper treatment adherence and hygiene are crucial, so follow-up care is important for both the physician and the patient.
View Article and Find Full Text PDF

Introduction: Intravenous immunoglobulin (IVIG) is an alternative for post-exposure prophylaxis if a vaccine is contraindicated and intramuscular immunoglobulin is unavailable. We retrospectively examined the effect of IVIG administration time on measles development in measles-contact infants younger than 6 months of age.

Methodology: Contact tracing of measles cases was performed by the Istanbul Public Health Directorate (IPHD) between August 24, 2012, and June 16, 2013.

View Article and Find Full Text PDF

Purpose: Postoperative pain is an acute pain that begins with surgical trauma and decreases as the tissue heals. The transversus abdominis plane (TAP) block is one of the abdominal field blocks used in the treatment of acute postoperative pain after lower abdominal surgery. This study aims to investigate the effects of dexamethasone added to a local anesthetic solution on postoperative analgesia in ultrasonography-guided TAP block.

View Article and Find Full Text PDF

LesionScanNet: dual-path convolutional neural network for acute appendicitis diagnosis.

Health Inf Sci Syst

December 2025

Section for Fisheries Technology, Institute of Aquatic Resources, DTU Aqua, Technical University of Denmark, 9850 Hirtshals, Denmark.

Acute appendicitis is an abrupt inflammation of the appendix, which causes symptoms such as abdominal pain, vomiting, and fever. Computed tomography (CT) is a useful tool in accurate diagnosis of acute appendicitis; however, it causes challenges due to factors such as the anatomical structure of the colon and localization of the appendix in CT images. In this paper, a novel Convolutional Neural Network model, namely, LesionScanNet for the computer-aided detection of acute appendicitis has been proposed.

View Article and Find Full Text PDF

Lactate is a product of anaerobic metabolism used to determine prognosis in critically ill trauma patients. This study investigates the mortality-predictive performance of lactate, lactate clearance, and lactate-to-albumin ratio (LAR) on admission in patients with polytrauma in a tertiary center's intensive care unit (ICU). Polytrauma patients in the ICU between June 2019 and June 2022 were evaluated.

View Article and Find Full Text PDF

Objective: In our study, we attempted to determine the accreditation process experience of hospital senior managers accredited by the Turkish Health Care Quality and Accreditation Institute (TUSKA). Along with the institutions' accomplishments through the accreditation program, the major challenges they faced during the accreditation process were revealed.

Methods: One of the qualitative research designs used was interpretive phenomenological analysis, which was carried out through semi-structured interviews with hospital senior managers.

View Article and Find Full Text PDF

Convolutional Neural Networks in the Diagnosis of Cervical Myelopathy.

Rev Bras Ortop (Sao Paulo)

October 2024

Departamento de Ortopedia e Traumatologia, Istanbul Faculty of Medicine, Istanbul University, Istambul, Turquia.

 Artificial intelligence technologies have been used increasingly in spine surgery as a diagnostic tool. The aim of the present study was to evaluate the effectiveness of the convolutional neural networks in the diagnosis of cervical myelopathy (CM) compared with conventional cervical magnetic resonance imaging (MRI).  This was a cross-sectional descriptive analytical study.

View Article and Find Full Text PDF

Referrals to emergency services are frequently made for acute appendicitis and renal colic. This conundrum of patients with acute appendicitis and right ureteral stones frequently presents itself to emergency physicians. The hematological parameters of patients suffering from acute appendicitis and right ureteral stones were compared in this study.

View Article and Find Full Text PDF

Dysfunction of PTEN-Associated MicroRNA Regulation: Exploring Potential Pathological Links in Type 1 Diabetes Mellitus.

Medicina (Kaunas)

October 2024

Department of Internal Medicine, Kanuni Sultan Suleyman Training and Research Hospital, Health Sciences University, Istanbul 34668, Türkiye.

Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease with T cell-mediated pathogenesis of pancreatic β-cell destruction, leading to insulin deficiency. MicroRNAs such as miR-223 and miR-106b, along with PTEN, have been reported to participate in the pathophysiology of diabetes and its complications. The current study has explored the expression of miR-223, miR-106b, and PTEN and their association with various clinical and biochemical parameters in subjects diagnosed with T1DM.

View Article and Find Full Text PDF

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

View Article and Find Full Text PDF
Article Synopsis
  • Anaphylaxis is a life-threatening allergic reaction, and understanding its triggers is crucial for preventing severe cases known as refractory anaphylaxis (RA).
  • A study analyzed data from 1,378 patients diagnosed with anaphylaxis, finding that 3.3% had RA, with a history of anaphylaxis being the strongest risk factor.
  • Other factors such as the use of beta-blockers/ACE inhibitors, exposure to IV contrast agents, and symptoms of low blood pressure were also linked to increased severity, highlighting the need for prompt treatment to improve patient outcomes.
View Article and Find Full Text PDF

Objective: This study was conducted to determine the relationship between bone mineral density, vitamin D level, and sleep quality in female patients with osteoporosis.

Methods: This descriptive correlational study included a total of 318 women diagnosed with osteoporosis. The data were collected using a patient identification form, including items for the plasma vitamin D level and bone mineral density score obtained by the dual-energy X-ray absorptiometry method, and the Pittsburgh Sleep Quality Index.

View Article and Find Full Text PDF
Article Synopsis
  • Stigma in multiple sclerosis (MS) leads to negative outcomes such as anxiety, depression, and social isolation, although there's currently no specific scale to measure it.
  • The study aimed to create and validate a "Multiple Sclerosis Stigma Scale (MSSS)" through a three-phase methodological approach, which included defining stigma, generating items, and testing the scale's psychometric properties.
  • The final 12-item MSSS showed strong reliability and validity in assessing stigma, revealing two main factors: discrimination and disclosure, making it suitable for use with Turkish MS patients.
View Article and Find Full Text PDF

: The aim of this study was to investigate the circulating levels of asprosin, clusterin, zinc-alpha-2-glycoprotein (ZAG), nuclear factor-kappa B (NF-κB), and peroxisome proliferator-activated receptor-gamma (PPAR-γ) in patients with T2DM in relation to microvascular and macrovascular complications. Measuring these biomarkers may provide insight into the pathophysiology of T2DM and indicate novel targets for the therapy of diabetes-related complications. : A total of 260 subjects consisting of four groups: healthy controls (Group-1), T2DM patients without complications (Group-2), T2DM patients with microvascular complications (Group-3), and T2DM patients with macrovascular complications (Group-4).

View Article and Find Full Text PDF

The First Surgery Experienced Through Virtual Reality: A Knee Surgery Case Report.

J Perianesth Nurs

October 2024

Surgical Medical Sciences, Department of Anesthesiology and Reanimation, Karadeniz Technical University, Trabzon, Turkey.

The decision to undergo surgery and the significance of the operating theater environment are influenced by several factors, which vary from person to person. Negative perceptions of the operating room environment can influence the decision to undergo surgery and the process of treatment. Virtual reality (VR) technology offers the potential to alter individuals' environmental encounters through the provision of diverse environmental perceptions.

View Article and Find Full Text PDF
Article Synopsis
  • * It found that the RSV only group had lower pH and higher rates of bronchiolitis, while the RSV with viral agents group experienced longer hospital stays and more severe symptoms.
  • * Additionally, cases with bacterial co-infections were generally younger and had different clinical markers, highlighting that combined viral and bacterial infections can worsen RSV severity and impact treatment approaches like High Flow Nasal Cannula-Oxygen Therapy.
View Article and Find Full Text PDF