2 results match your criteria: "Kantonsspital Aarau and faculty at the University of Basel[Affiliation]"

Article Synopsis
  • The study investigates the effectiveness of a procalcitonin-based antibiotic stewardship program in community hospitals to reduce inappropriate antibiotic use, addressing the global concern of antimicrobial resistance.
  • Conducted as a matched cohort study, the research compared patients from hospitals implementing the procalcitonin protocol with those from hospitals without it, focusing on various demographic and clinical factors.
  • Results indicated that patients in procalcitonin cohort hospitals received 1.47 fewer days of antibiotic therapy, though there was a noted increase in acute kidney injury, but no significant differences in length of stay or other adverse outcomes.
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Objective: Procalcitonin (PCT) is a biomarker that may help providers optimize antibiotic (AB) therapy. Numerous clinical trials have demonstrated the utility of PCT-guided decision algorithms in treating lower respiratory tract infections and sepsis, but evidence from real-world studies is limited. This study sought to evaluate the effects of PCT on select clinical outcomes in community hospitals.

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