[A case report of thrombosed Björk-Shiley valve in aortic position diagnosed using transtelephone PCG monitoring].

We report a successful elective re-AVR and MVR 10 years after AVR with aortic root enlargement and OMC. The patient was a 41-year-old woman. The diagnosis of thrombosed Björk-Shiley (B-S) valve was first suspected by transtelephone PCG monitoring and reconfirmed by the frequency analysis of prosthetic valve sounds and the aortography preoperatively.

[Immunoblastic lymphadenopathy-like T cell lymphoma accompanied by autoimmune hemolytic anemia].

A 62-year-old man was admitted to our hospital because of generalized lymphadenopathy, fever and skin eruptions. The histology of the right cervical lymph nodes showed immunoblastic lymphadenopathy (IBL)-like T cell lymphoma. His laboratory data were as follows: hemoglobin concentration 7.

[alpha-Interferon in the treatment of essential thrombocythemia].

Two patients with essential thrombocythemia were successfully treated by administering native alpha-interferon (alpha-IFN). One patient was a 38-year-old man in whom thrombocytosis was found accidentally. His platelet count on admission was 880,000/microliters and megakaryocytes increased.

[A case of chronic progressive external ophthalmoplegia associated with familial hypercholesterolemia].

A 52-year-old woman with chronic progressive external ophthalmoplegia (CPEO) with familial hypercholesterolemia (FH) was reported. Her mother died from heart disease, and her elder sister has hypercholesterolemia with swelling of Achilles tendons. She had slowly progressive external ophthalmoplegia, bilateral ptosis, swelling of Achilles tendons since twenties.

Application of MEN 203 as a polymorphic DNA probe in screening multiple endocrine neoplasia 2a.

Multiple endocrine neoplasia 2a (MEN 2a) is known to be genetically linked to a locus on chromosome 10. The application of polymorphic DNA probes for the region has made it possible to identify carriers of the disease susceptible gene. We performed DNA analysis for a newly found non-Caucasian MEN 2a family using MEN 203 as a probe.

[Fundamental studies on "M. TB probe assay kit" for the identification of Mycobacterium tuberculosis].

DNA probe assay kit for the identification of Mycobacterium tuberculosis was evaluated. This kit is based on beads capture method and using a 20 well assay tray. The culture isolate is suspended with 0.

[A clinical study on cefdinir in pediatric field].

Cefdinir (CFDN) was administered to pediatric patients with acute infectious disease. A summary of the results obtained is as follows. 1.

[A case of successful surgical repair for congenital corrected transposition of the great arteries associated with Ebstein's malformation and diverticulum of atrialized ventricle].

Congenital corrected transposition of the great arteries (C-TGA) is frequently associated with VSD and PS. Systemic atrioventricular valve regurgitation is also sometimes present in patients with C-TGA. It is though that left-sided A-V valve regurgitation is caused by the deformities of the tricuspid valve (TV) or intolerance of TV and the right ventricle (RV) against systemic pressure load.

Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis.

Immunohistochemical analysis of the inflammatory cells and complement C3 in the rat skeletal muscle was performed chronologically in bupivacaine-induced myonecrosis. At 30 minutes after injection, polymorphonuclear leukocytes appeared and increased in number, with a peak value at 12 hours, while macrophages reached the highest level at 2 days. In contrast, T cells comprised only a small population.

Contrast radiography and effects of thoracic sympathetic ganglion block--anatomical analysis.

Thoracic sympathetic ganglion block is less effective than lumbar sympathetic ganglion block due to differences in the anatomical structure of these regions. Contrast radiographic findings and an analysis of the effects of lumbar sympathetic ganglion block have been reported, but there are few reports concerning thoracic sympathetic ganglion block. The relationship between contrast radiography findings and the effects of thoracic sympathetic ganglion block were studied in 131 block procedures which mainly had hyperhidrosis.

[Assessment of the permeability of the pulmonary microvasculature using radiotracers in a case of adult respiratory distress syndrome].

A 48-year-old man with small cell lung cancer developed ARDS, and massive pulmonary edema fluid was obtained with the fiberoptic bronchoscopy. The pulmonary edema fluid to serum ratios of total protein and albumin were 0.72 and 0.

[Sampling of specimens for laboratory examinations].

By the construction of hospital total system, marked developments, such as efficiency and labor-saving of work, have introduced to clinical practice and medical managements. Almost the same developments were also acquired by virtue of computerization in laboratory analysis. In our hospital, the Laboratory Information System (LIS) was connected in on-line mode with the Shared Hospital Information System (SHIS) and the Medical Data Administration System (MDAS).

Sensitive detection of viral antigens with a new method, "laser magnet immunoassay".

A new method, "laser magnet immunoassay" (LMIA), has been developed for sensitive detection of viral antigens. Target viruses captured on microbeads were made to react with antibodies labeled with magnetite particles. In a magnetic field, magnetically labeled antigens dispersed in water were attracted to and concentrated at one point on the surface, resulting in the lifting up of a small surface area.

[A case report of definitive repair for pulmonary atresia and intact ventricular septum associated with aortic valve regurgitation].

A successful definitive repair for a 10-year-old girl with pulmonary atresia and intact ventricular septum (PA.IVS) associated with aortic valve regurgitation is described. The Fontan type repair was not indicated in this case because of the left ventricular dysfunction due to aortic valve regurgitation and inadequate size of the pulmonary artery.

[Clinical usefulness of 67Ga-citrate scintigraphy combined early image in malignant lymphoma--detection of abdominal lesions].

In order to improve the diagnostic accuracy in detecting abdominal lesions of malignant lymphoma, we studied prospectively the usefulness of 67Ga-citrate scintigraphy combined 5 to 6-hour early image with conventional 72-hour delayed image after injection. During the period from July 1986 to September 1988, total 41 67Ga-citrate scintigrams performed on 28 patients with malignant lymphoma (3 Hodgkin's disease, 25 non-Hodgkin lymphoma) were evaluated between early and delayed image regarding to such points as follows; 1) the physiologic bowel uptake of 67Ga-citrate, 2) detection of abdominal lesions indicated by other diagnostic modalities involving computed tomography, lymphography and ultrasonography. Following results were obtained: 1) Prominent bowel uptake of 67Ga-citrate thought to be difficult to interpret the scintigram was observed in only 1 of 41 (2%) on early image versus 13 of 41 (32%) on delayed image.

Coronary revascularization in a child with Kawasaki disease: use of right gastroepiploic artery.

In coronary insufficiency produced by Kawasaki disease, myocardial revascularization using saphenous vein, internal mammary arteries, and a combination of both grafts has been performed with considerable success. Recently, we successfully used a right gastroepiploic artery as another conduit in coronary revascularization of a 6-year-old boy with Kawasaki disease. Use of the gastroepiploic artery was feasible even in a small child, and this technique is expected to contribute to long-term graft patency as an arterial graft adjunct to internal mammary arteries.

[Atypical infiltration of megakaryocytes into the liver and spleen in a case of refractory anemia].

A 72-year-old man was admitted to our hospital because of general malaise. The peripheral blood showed pancytopenia (WBC 800/microliters, RBC 970,000/microliters, Plt 95,000/microliters). The bone marrow smear revealed morphological abnormalities in three lineage without increase in blasts.

[A case report of Ebstein's anomaly treated with Carpentier's procedure].

A 42-year-old male patient was admitted with congestive heart failure. Echocardiogram and cardiac angiogram revealed Ebstein's anomaly and severe tricuspid valve incompetence. He underwent Carpentier's procedure for the treatment of Ebstein's anomaly.

Neurinoma of the oculomotor nerve: CT and MR features.

The authors present a case of neurinoma of the oculomotor nerve without evidence of von Recklinghausen disease. The literature is reviewed and CT and magnetic resonance findings are discussed.

[Low-dose etoposide in the treatment of chronic myelomonocytic leukemia].

Two cases of chronic myelomonocytic leukemia (CMML) which were successfully treated with low dose etoposide are reported. One case was treated with oral etoposide in daily dose of 25 mg for 3d a week, another case in dose of 50 mg/day. Their white blood cell counts became normal and monocytes decreased after the treatment with etoposide.