208 results match your criteria: "Kanto Gakuin University.[Affiliation]"

Background: The anticancer activity and radiosensitizing effect of Auranofin, an an-tirheumatic and an approved gold metallic drug, have been investigated from multiple perspectives. In this study, the action of the new gold complex compound TPN-Au(I)-MM4 was compared with that of auranofin.

Methods: The inhibitory effect of 10 μM and 50 μM concentrations on cell proliferation was investigated using the human colon cancer cell lines HCT116 and SW480.

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High-flow nasal oxygen therapy (HFNO) is highly versatile and employed in varied situations, including after extubation, in cases of respiratory failure, and at the end of life. However, its impact on swallowing function is not yet elucidated. Therefore, this scoping review aimed to clarify how HFNO affects swallowing function and whether it poses a risk for aspiration pneumonia.

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Article Synopsis
  • This systematic review and meta-analysis assessed how enhanced rehabilitation after hospital discharge affects the quality of life (QOL) for survivors of critical care, following PRISMA guidelines and examining data from several major health databases until January 2024.
  • The review included nine randomized controlled trials (RCTs) with 573 participants, finding that enhanced rehabilitation showed no significant improvement in physical QOL but did result in a higher mental QOL score (low-certainty evidence).
  • Adverse events' impact was uncertain, with mixed reports from the studies; some had no adverse events, while others noted serious incidents, indicating very low-certainty evidence on this issue.
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Aim: This study aimed to clarify factors that affect turnover intention of nurses in Japanese nursing homes (NHs).

Methods: Cross-sectional nationwide self-administered anonymous questionnaire survey was conducted among 2000 nurses and 1000 directors from 1000 NHs. Data were collected between December 2019 and January 2020.

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Objective: Healthcare workers involved in, and negatively affected by, patient safety incidents are referred to as second victims. The Second Victim Experience and Support Tool-Revised (SVEST-R) can reveal the second victim's degree of negative experiences and the desirability of the support options. However, a Japanese version of the SVEST-R (J-SVESTR) has not yet been developed.

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Article Synopsis
  • Aureispira marina is a marine bacterium with the ability to glide, found along Thailand's southern coast, notable for containing ceramide as a primary lipid.
  • Previous research identified the structure of its unsaturated 2-hydroxy-fatty acid but did not clarify its double bond configuration.
  • In the current study, the configuration was determined to be trans by synthesizing and analyzing a specific fatty alcohol, leading to a revision in the understanding of the cellular fatty acid composition in Aureispira species.
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Aurantiochytrium sp. 18W-13a, a marine heterotrophic protist belonging to the genus thraustochytrid, is known to accumulate high levels of squalene and carotenoids. Nowadays, the mutagenesis breeding of microorganisms is still widely practiced because the induced mutations of DNA do not involve the permanent integration of heterologous DNA sequences.

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Purpose: The effect of increased physical activity duration on functional recovery in older inpatients in subacute settings is not well established. This study aimed to investigate the relationship between physical activity and functional recovery in older patients receiving post-acute and subacute care.

Methods: We analyzed cohort data of hospitalized older patients (age ≥ 65 years) in the post-acute rehabilitation units.

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Aims: To develop a scale to assess difficulties that nurses experience when collaborating with physicians in responding to clinical deterioration during night shifts and identify factors associated with scoring using the developed scale.

Methods: A web-based questionnaire with a draft scale, the Nighttime Collaboration Difficulties between Nurses and Physicians for Nurses (NCDNP-N), was distributed to nurses working night shifts in acute-care hospitals across Japan. Data were collected between July and October 2023.

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Introduction The physical, cognitive, and psychiatric disorders that occur in patients after leaving the intensive care unit (ICU) are collectively called post-intensive care syndrome (PICS). Moreover, PICS-family (PICS-F) refers to the long-term psychological and social disorders that occur in the family. The symptoms of PICS-F can be psychological, and stress is a known cause of these symptoms.

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Background: Intensive care units (ICUs) have mortality rates of 10%-29% owing to illness severity. Postintensive care syndrome-family affects bereaved relatives, with a prevalence of 26% at 3 months after bereavement, increasing the risk for anxiety and depression. Complicated grief highlights issues such as family presence at death, inadequate physician communication and urgent improvement needs in end-of-life care.

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Aims: This study examined whether educational methods utilizing extended reality (XR) improve pre-registration nursing students' knowledge, skills, confidence, and satisfaction compared with traditional methods.

Design: We conducted a systematic review and meta-analysis of the effectiveness of XR in nursing education based on the Cochrane methodology.

Data Sources: Randomized controlled trials (RCTs) were searched in MEDLINE, CINAHL, ERIC, Web of Science, Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi from inception of each database to March 21, 2024.

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Background: Responding to inpatient deterioration is less favorable at night than during the day, and this may be related to barriers in collaboration between physicians and nurses. However, there had been no way to assess the problem. This study aimed to develop a scale for physicians to measure difficulties in nighttime collaboration with nurses in response to deteriorating inpatients and to identify factors associated with the developed scale scores.

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Silicon Microring Resonator Biosensor for Detection of Nucleocapsid Protein of SARS-CoV-2.

Sensors (Basel)

May 2024

Department of Science and Engineering, Kanto Gakuin University, 1-50-1 Mutsuura-higashi, Kanazawa-ku, Yokohama 236-8501, Japan.

A high-sensitivity silicon microring (Si MRR) optical biosensor for detecting the nucleocapsid protein of SARS-CoV-2 is proposed and demonstrated. In the proposed biosensor, the surface of a Si MRR waveguide is modified with antibodies, and the target protein is detected by measuring a resonant wavelength shift of the MRR caused by the selective adsorption of the protein to the surface of the waveguide. A Si MRR is fabricated on a silicon-on-insulator substrate using a CMOS-compatible fabrication process.

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Objectively measured physical activity volume serves as a predictive factor for functional recovery in patients with stroke. Malnutrition, a frequent complication of stroke, may influence the relationship between physical activity and functional recovery. This study aimed to examine the association between physical activity volume and functional recovery in patients with stroke, stratified by their nutritional status.

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Death rattle: palliative nursing practices Delphi study.

BMJ Support Palliat Care

December 2024

Department of Adult Health Nursing, Graduate School of Health Care Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Japan.

Objectives: Interventions for patients with death rattle remain under consideration, and their families strongly acknowledge the need for improved care. However, few reports exist concerning specific and comprehensive nursing practices for them. This study aimed to clarify nursing practices for patients with death rattle and their families in hospital wards and examine each practice's importance.

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Article Synopsis
  • Core-collapse supernovae (CCSNe) are super powerful explosions that happen when big stars die, creating things like neutron stars and black holes.
  • This review explains how CCSNe work, focusing on the importance of particles called neutrinos in these explosions.
  • It also looks into the details of how neutrinos interact and discusses some of the unresolved questions scientists still have.
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In this study, a micropowder blasting system with varying processing temperatures was proposed to control the cross-sectional shape of a channel processed on a glass substrate. Based on an analysis of the processing temperature-dependence of the dynamic viscoelastic properties of a commercial mask material for micropowder blasting, a processing temperature control system that can be installed in a micropowder blasting machine was designed. The erosion of the mask during micropowder blasting depended on the loss tangent in dynamic viscoelasticity, and showed a maximum value at a processing temperature of 100 °C.

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On NFPs with high social impact that avoid concentrating on a few activities.

F1000Res

February 2024

Department of Business Administration, Kanto Gakuin University, Yokohama, 2310016, Japan.

An influential piece of literature on effective altruism insists that not-for-profit organizations (NFPs) should concentrate their investments on a few activities to maximize their social return on investment (SROI) ratio. However, this creates greater risk for an NFP than building a portfolio of investments in activities. This study investigates whether it is desirable for executives and contributors of NFPs to build a portfolio rather than maximize the expected SROI ratio, and if so, how to build one.

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Purpose: Factors associated with positive mental health in children with chronic diseases remain unclear. Supporting the development of positive mental health in children with chronic diseases can enhance their mental health throughout childhood and adulthood. This study aimed to identify the factors associated with positive mental health among Japanese young adults with a history of chronic pediatric diseases.

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Probing Electronic Band Structures of Dielectric Polymers via Pre-Breakdown Conduction.

Adv Mater

December 2024

Electrical Insulation Research Center, University of Connecticut, 97 N Eagleville Rd, Storrs, CT, 06269, USA.

The electronic band structure, especially the defect states at the conduction band tail, dominates electron transport and electrical degradation of a dielectric material under an extremely high electric field. However, the electronic band structure in a dielectric is barely well studied due to experimental challenges in detecting the electrical conduction to an extremely high electric field, i.e.

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The 5α condensate state in Ne.

Nat Commun

December 2023

College of Science and Engineering, Kanto Gakuin University, Yokohama, 236-8501, Japan.

The formed He (α) clusters consisting of two neutrons and two protons can be a building block in light nuclear systems. Intriguingly, these alpha clusters could potentially form alpha condensate states within the nuclear system. The Hoyle state at 7.

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In this paper, a knittle pressure sensor was designed and fabricated by coating graphene/Polyvinylidene Fluoride nanocomposite on the knitted polyester substrate. The coating was carried out by a dip-coating method in a nanocomposite solution. The microstructure, surface properties and electrical properties of coated layers were investigated.

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Public facilities that have NIMBY (not in my backyard) structure involve both a social dilemma, in which individuals' decisions to prevent the worst outcomes for themselves undermine the public interest, and a moral dilemma focused on the majority versus the minority. This study examined the cognitive-neural processes in judging whether to prioritize the site residents or the citizenry as a whole within the context of NIMBY. Our ROIs were the right angular gyrus being related to concern about the worst possible outcomes for others and oneself, the amygdala associating with emotional aversion to prioritizing the majority, and the vmPFC, which integrates the aversion into "all things considered" judgments.

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Background: Exercise therapy is the key to preventing admission of patients with type 2 diabetes mellitus (T2DM). However, a few studies have examined the effects of exercise therapy on patients with T2DM undergoing inpatient diabetes self-management education and support (IDSMES).

Objective: This study investigated whether exercise therapy influenced the incidence of admission after discharge in patients with T2DM undergoing IDSMES.

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