1 results match your criteria: "Kansai Medical University. mkojima@dokkyomed.ac.jp[Affiliation]"
Dic (17;20) (p11;q11) preceded MLL gene amplification in a patient with de novo mixed-lineage leukemia.
J Clin Exp Hematop
March 2016
First Department of Internal Medicine, Kansai Medical University.
Article Synopsis
- A 65-year-old woman was diagnosed with a rare type of leukemia that mixes different blood cell types and has problems with important genes.
- Her bone marrow had a lot of special cancer cells that looked different and had issues with the p53 gene, which usually helps prevent cancer.
- Scientists found changes in other genes, meaning her leukemia might be due to a mix of genetic problems, including the MLL gene being overly active because of the p53 gene being damaged.