Efficacy of single glaucoma medication in combined latanoprost and timolol XE therapy in patients with open-angle glaucoma and ocular hypertension: a discontinuation study.

Purpose: To study the effect of single drug discontinuation in combined timolol XE 0.5% and latanoprost 0.005% treatment.

[Causes of patients' non-adherence with glaucoma medication dosing: systemic classification based on dosing schedule].

Purpose: To study the causes of patients' nonadherence with the instruction of glaucoma medication dosing and to analyze them based on the dosing schedules by means of systemic classification.

Methods: Four hundred twenty eight patients who had been prescribed glaucoma medication for at least six months were studied. Adherence was ascertained by means of a predetermined questionnaire.

Efficacy of single glaucoma drug in combined timolol XE, latanoprost and brinzolamide therapy: a discontinuation study.

Purpose: To study the efficacy of a single drug in patients with primary open angle glaucoma and ocular hypertension who were receiving timolol XE 0.5%, latanoprost 0.005% and brinzolamide 1% with its discontinuation.

Ultraslim endoscopy with flexible spectral imaging color enhancement for upper gastrointestinal neoplasms.

Aim: To conduct a preliminary study on the effect of flexible spectral imaging color enhancement (FICE) used in combination with ultraslim endoscopy by focusing on the enhanced contrast between tumor and non-tumor lesions.

Methods: We examined 50 lesions of 40 patients with epithelial tumors of the upper gastrointestinal tract before endoscopic submucosal dissection using ultraslim endoscopy with conventional natural color imaging and with FICE imaging. We retrospectively investigated the effect of the use of FICE on endoscopic diagnosis in comparison with normal light.

Intra-articular synovial cyst of the knee joint: a case report.

Synovial cysts occur secondary to injury, mucinous degeneration or tumours. We report a patient with snapping of the knee joint caused by a synovial cyst located near the patellofemoral joint which developed as a result of minor trauma.

Evaluation of the need to discontinue antiplatelet and anticoagulant medications before cataract surgery.

Purpose: To assess the risk for intraoperative and postoperative bleeding associated with antiplatelet and/or anticoagulant treatment in patients having uneventful phacoemulsification.

Setting: Kokura Memorial Hospital, Kitakyusyu, Japan.

Methods: In a nonrandomized case series, consecutive patients had phacoemulsification and intraocular lens implantation under sub-Tenon anesthesia.

A comparison of the intraocular pressure lowering effect of adjustable suture versus laser suture lysis for trabeculectomy.

Purpose: To compare the intraocular pressure lowering effect of adjustable sutures and laser suture lysis for trabeculectomy in eyes with primary open angle glaucoma.

Methods: Fifty patients with primary open angle glaucoma were studied. Eyes were assigned randomly to either trabeculectomy augmented with mitomycin C with adjustable sutures or with laser suture lysis.

Efficacy of N-acetylcysteine and aminophylline in preventing contrast-induced nephropathy.

Background: Contrast-induced nephropathy (CIN) is one of the important complications of coronary angiography (CAG) and percutaneous coronary intervention (PCI), especially in patients with chronic kidney disease (CKD). Prophylactic administration of N-acetylcysteine (NAC) and aminophylline has been reported to be effective in some trials, but the results still remain controversial. We investigated the efficacy of NAC or aminophylline in preventing CIN.

[A case of advanced gastric cancer with histological complete response after S-1 chemotherapy].

A 58-year-old man of unresectable gastric cancer was treated with S-1 (120 mg/body/day) after gastrojejunostomy. After 5 courses of orally administration of S-1 for 4 weeks and withdrawal for 2 weeks, partial response (PR) was obtained clinically and distal gastrectomy was performed. The histological diagnosis showed no residue of carcinoma with both HE and immunohistochemical staining.

[A case of long-term survival of recurrent gastric cancer successfully treated with multidisciplinary therapy].

A 73-year-old male patient underwent total gastrectomy for advanced gastric cancer in December 2000. The final diagnosis was 1 MU, ant, type 3, 67x47 mm, pT2 (ss), pN1 (#1, 3, 4d), sP0, sH0, CY0, cM0, fStage II, tub 2, int, inf beta, ly3, v3, 2 L, post, type 2, 42x40 mm, pT2 (mp), pN1 (#1, 3, 4d), sP0, sH0, CY0, cM0, fStage II. Although we began adjuvant chemotherapy with UFT 300 mg/day, a solitary liver metastasis in the S6 sub-segment of the liver was diagnosed 15 months after the first operation.

[Central nervous system leukemia mimicking rapidly progressive HTLV-1 associated myelopathy].

A 79-year-old woman was suffered from rapidly progressive paresthesia of lower limbs and gait disturbance. After one month, she showed flaccid paraplegia and hyperreflexia in the lower limbs with positive Babinski signs. Anti-HTLV-1 antibody titer was elevated in the serum, but negative in the cerebrospinal fluid (CSF).

Stenosis of gastric body as a rare complication after endoscopic submucosal dissection for multiple gastric epithelial tumors.

We experienced a rare case of stenosis of the gastric body, a wider tract, that occurred after multiple, wide endoscopic resection five times for four lesions of early gastric cancer and gastric adenomas. We report this case as a sentinel experience of endoscopic submucosal dissection of the stomach.

[Aneurysmal subarachnoid hemorrhage in the Yaeyama Islands, Japan, from 1989 to 2002].

The aim of this study was to analyze epidemiological and clinical data of patients with aneurysmal subarachnoid hemorrhage (SAH) in the Yaeyama islands, an isolated subtropical region of Japan. A total of 94 patients (31 men and 63 women, mean age 57.3 years) were diagnosed as having non-traumatic SAH during a 13-year period from 1989 to 2002.