Electromagnetic field-assisted cell-laden 3D printed poloxamer-407 hydrogel for enhanced osteogenesis.

3D bioprinted hydrogel has gained enormous attention, especially in tissue engineering, owing to its attractive structure and excellent biocompatibility. In this study, we demonstrated that 3D bioprinted cell-laden 'thermoresponsive' poloxamer-407 (P407) gels have the potential to stimulate osteogenic differentiation of apical papilla stem cells (SCAPs) under the influence of low voltage-frequency (5 V-1 Hz, 0.62 mT) electromagnetic fields (EMFs).

Reduced graphene oxide-incorporated calcium phosphate cements with pulsed electromagnetic fields for bone regeneration.

Natural calcium phosphate cements (CPCs) derived from sintered animal bone have been investigated to treat bone defects, but their low mechanical strength remains a critical limitation. Graphene improves the mechanical properties of scaffolds and promotes higher osteoinduction. To this end, reduced graphene oxide-incorporated natural calcium phosphate cements (RGO-CPCs) are fabricated for reinforcement of CPCs' characteristics.

Fabrication and characterization of 3D printable nanocellulose-based hydrogels for tissue engineering.

Cellulose nanocrystal (CNC)-based hydrogels are considered attractive biomaterials for tissue engineering due to their excellent physicochemical properties. Hydrogels of alginate and gelatin were prepared with or without CNCs and printed using a CELLINK® BIOX 3D bio-printer. The 3D-printed scaffolds were characterized by Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, transmission electron microscopy (TEM), and scanning electron microscopy (SEM).

Enhanced osteogenesis of mesenchymal stem cells on electrospun cellulose nanocrystals/poly(ε-caprolactone) nanofibers on graphene oxide substrates.

Cellulose nanocrystals (CNCs) have received a great amount of attention to the production of micro/nano-platforms for tissue engineering applications. CNCs were extracted from rice husk biomass and characterized by different spectroscopic techniques. The biocompatibility of the extracted CNCs was revealed by the WST-1 assay technique in the presence of human mesenchymal stem cells (hMSCs) after different time intervals.

Nanocellulose-based polymer hybrids and their emerging applications in biomedical engineering and water purification.

Nanocellulose, derived from cellulose hydrolysis, has unique optical and mechanical properties, high surface area, and good biocompatibility. It is frequently used as a reinforcing agent to improve the native properties of materials. The presence of functional groups in its surface enables the alteration of its behavior and its use under different conditions.