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RSC Adv
April 2022
Faculty of Biological Science and Technology, Institute of Science and Engineering, Kanazawa University Kakuma-machi Kanazawa 920-1192 Japan
We report biocompatible materials for cryostorage of unstable proteins such as cancer-related enzyme, -acetylglucosaminyltransferase-V (GnT-V). GnT-V activity and the amount of protein after freezing were better retained in synthetic zwitterion solutions than in the glycerol solution. This study highlights the potential utility of synthetic zwitterions as novel cryoprotectants.
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