A necropsy of a Creutzfeldt-Jakob disease patient revealed severe brain damage, particularly in the lateral geniculate body and pregeniculate body, while other areas like the superior colliculus remained intact.
The patient exhibited unique EEG features, including photo-stimulated giant spikes that suppressed periodic synchronous discharges and a loss of pupillary light reflex.
This suggests that the visual pathway plays a role in the unusual symptoms observed in this case of CJD.