A Lab-Based Study to Assess the Surface Roughness of Various Investments: An Original Research.

Introduction: Surface roughness of the crowns is dependent on the pattern material used for the making as well as the procedure of investing. The study was aimed to examine the impact of various pattern materials and investment procedures on the surface roughness of nickel-chromium alloy raw castings.

Materials And Methods: An study was piloted at a tertiary care hospital.

Antibacterial Effect of the Nanoparticle-Incorporated Primers Commonly Used for Orthodontic Bonding.

Background: Nanosized antibacterial agents can be used to prevent biofilm buildup on orthodontic appliances and auxiliaries, limiting microbial adherence and preventing caries. Nanoparticles (NPs) can enhance the antibacterial properties of orthodontic materials due to their smaller particle size and larger surface area.

Materials And Methods: The study's material analysis was divided into four groups, numbered I through IV, using Transbond XT Primer as a control and modifying group I by adding various antibacterial agents.

Dental Services and their Awareness and Utilization among the Health Care Workers in a South Indian District - A Cross Sectional Study.

Aim: The present research was carried out to evaluate the amount of usage of dental care opportunities and also to assess the problems faced by health care workers (HCWs) of a south Indian district in using dental services.

Methodology: This study had around 500 participants who belonged from various health care sectors who were selected with the help of multistage sampling. The data obtained from this cross-sectional research was analysed statistically using SPSS 22.

The Impact of the Gender on the Pulp Vitality Testing for the Various Types of the Conducting Media: An Original Research.

Introduction: To identify gender-based differences in pulpal sensory thresholds in human teeth utilizing various conducting media.

Materials And Methods: The study involved 50 participants of both genders equally distributed. The maxillary central incisors were the teeth selected for the intervention.

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research.

Aim: This study was intended to assess and relate the clinical anesthetic effectiveness of tramadol hydrochloride and lidocaine.

Methodology: A clinical randomized split-mouth study was piloted among 40 patients who were otherwise healthy but needed to have their maxillary first premolars extracted bilaterally for orthodontic reasons were considered in the research. In each subject on one side (quadrant) of the arch 1.

Evaluation of the Curing of the Primer on Shear Bond Strength of Orthodontic Brackets: An Original Research.

Background: The aim of this study was to evaluate the effect of separately curing the unfilled resin for increased bond strength of the orthodontic brackets as the literature shows both studies that support and contradict this aspect.

Methodology: The sample consisted of 120 specimens randomly grouped into four of 30. The tooth was cleaned of tissue and debris and stored in a distilled water solution until the procedures of bonding.

An In Vitro Investigation of the Role of Implant Abutment Materials on the Fracture Resistance and Failure Mode of Implant-Supported Restorations.

Background: Implant-supported restorations have gained popularity in modern dentistry, and the choice of abutment material is crucial for their long-term success. This in vitro study aimed to evaluate the fracture resistance and failure mode of implant-supported restorations using different abutment materials.

Methods: Ninety standardized implant-supported restorations were included in the study.

Generation of Cancer Stem Cells by Co-Culture Methods.

Cancer stem cells (CSCs) exhibit intricate regulatory dynamics within the tumor microenvironment, involving interactions with various components like mesenchymal stem cells (MSCs), adipocytes, cancer-associated fibroblasts (CAFs), endothelial cells, tumor-associated macrophages (TAMs), and other immune cells. These interactions occur through complex networks of cytokines, inflammatory factors, and several growth factors. Diverse techniques are employed to generate CSCs, including serum-free sphere culture, chemotherapy, and radiation therapy.

Perinatal depression and its associated risk factors during the COVID-19 pandemic in low- and middle-income countries: a systematic review and meta-analysis.

Purpose: Perinatal depression significantly impacts maternal and child health, with further complexities arising during the COVID-19 pandemic. This review is the first to comprehensively synthesize evidence on the prevalence of perinatal depression and its associated risk factors in Low- and Middle-Income Countries (LMICs) during the pandemic period.

Methods: The study protocol was registered in PROSPERO (CRD42022326991).

Corrigendum: Cytokinins: a genetic target for increasing yield potential in the CRISPR era.

[This corrects the article DOI: 10.3389/fgene.2022.

Oral Health-related Quality of Life Assessed by Child: Oral Impacts on Daily Performances Index and Their Association with Dental Caries Prevalence and Gingival Bleeding Status of 12-year-old School Children in Bhubaneswar City.

Aim And Objective: To assess the association, if any, between oral health-related quality of life (OHRQoL) measured using child oral impact on daily performances (C-OIDP) index and dental caries and gingival bleeding status among 12-year-old school children of Bhubaneswar city.

Materials And Methods: A cross-sectional descriptive study was conducted, and the data were collected using child oral impacts on daily performances index, a closed-ended questionnaire among the 12-year-old school children of Bhubaneswar, Odisha, India, to find out the association between dental caries prevalence among gingival bleeding status. Data were analyzed using descriptive statistics, and Chi-squared tests were used to determine the significant differences in the variable of interest.

screening of phytoconstituents as potential anti-inflammatory agents targeting NF-κB p65: an approach to promote burn wound healing.

Chronic burn wounds are frequently characterised by a prolonged and dysregulated inflammatory phase that is mediated by over-activation of NF-κB p65. Synthetic wound healing drugs used for treatment of inflammation are primarily associated with several shortcomings which reduce their therapeutic index. In this scenario, phytoconstituents that exhibit multifaceted biological activities including anti-inflammatory effects have emerged as a promising therapeutic alternative.

Health Warnings on Tobacco Packages: A Compliance Assessment Study Around Educational Institutions in Bhubaneswar, India.

Background Graphic health warning labels (HWLs) on tobacco product packaging have been identified by the World Health Organization (WHO) as a cost-effective policy intervention to warn consumers about the health risks of tobacco. Compliance with HWLs shields young individuals from tobacco marketing influences and exposes users to health warnings. Assessing compliance with health warning labels would provide insights into the state of law implementation.

Nanotechnological interventions in bacteriocin formulations - advances, and scope for challenging food spoilage bacteria and drug-resistant foodborne pathogens.

Food spoilage bacteria (FSB) and multidrug-resistant (MDR) foodborne pathogens have emerged as one of the principal public health concerns in the twenty first century. The harmful effects of FSB lead to economic losses for the food industries. Similarly, MDR foodborne pathogens are accountable for multiple illnesses and pose a threat to consumers.

Proficiency of Clear Aligner Therapy: A Systematic Review and Meta-Analysis.

The aim of this study was to evaluate the efficacy and efficiency of orthodontic treatment using clear aligner therapy (CAT). This efficiency was measured using the Peer Assessment Rating (PAR) index, the American Board of Orthodontics (ABO) index, or the similarity between the final ClinCheck and the final scanned models. A search was done electronically between 1998 and 2021 using the Cochrane Library, PubMed, and Google Scholar databases.

Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy.

Breast cancer is the most prevalent form of cancer in women globally, and TNBC (triple-negative breast cancer) is its aggressive type since it lacks the usual targets. JAK2/STAT3 pathway can be an important lead in anticancer drug discovery, as restraining the downstream signalling of this pathway results in the induction of cell apoptosis. Moreover, various limitations associated with chemotherapy are the reason to find an alternative herbal-based therapy.

Identification of potential flavonoid compounds as antibacterial therapeutics against Klebsiella pneumoniae infection using structure-based virtual screening and molecular dynamics simulation.

Klebsiella pneumoniae, which is among the top three pathogens on WHO's priority list, is one of the gram-negative bacteria that doctors and researchers around the world have fought for decades. Capsular polysaccharide (CPS) protein is extensively recognized as an important K. pneumoniae virulence factor.

A Study on Speech Analysis in Acquired Maxillary Defect Patients Treated with Maxillary Obturator.

Aim: The aim of the present study was to assess the speech analysis in acquired maxillary defect patients treated with maxillary obturator.

Materials And Methods: Total of 16 patients were considered in the study. The age group of these patients ranged from 40 to 75 years with a mean age of 59.

Antimicrobial Efficacy of Three Different Mouthwashes on Periodontal Pathogens-An Study.

Aim: The aim of this research was to identify the antimicrobial effectiveness of three different mouthwashes on periodontal pathogenic microorganisms.

Materials And Methods: 2 periodontal disease-causing microorganisms, i.e.

Effect of Dental Varnishes in Prevention of Enamel Demineralization Adjacent to Orthodontic Brackets.

Aim: The aim of the current research was to assess the ability of different dental varnishes in averting enamel demineralization adjoining the orthodontic brackets.

Materials And Methods: Seventy-five premolars devoid of dental caries that were subjected to extraction for orthodontic purposes were employed in this research. The surface of enamel was etched with 37% phosphoric acid and subjected to primer application.

Tribal women empowerment through entrepreneurship: evidence from Mayurbhanj District, Odisha.

Introduction: Empowering women in a tribal context through entrepreneurship is an approach for enabling and making them economically and socially viable. This paper aims to highlight entrepreneurship in a specific tribal context and provide insight on some instances or cases relating to women's empowerment. Although there are many initiatives from international organizations and governmental institutions to support women entrepreneurs, especially tribal women, they suffer from isolation as a result of their language and lifestyle differ from the rest of society, which made the growth of their business and ability to compete arduous, and thus affected their ability to make various decisions in their lives.

Effect of Neonatal Factors on the Eruption of Primary Teeth in Children: A Longitudinal Prospective Cohort Study.

Introduction: Eruption of first primary teeth is a normal physiological process. Antenatal nutritional deficiency and prenatal and neonatal factors play an important role in eruption of primary teeth. Neonatal factors, such as gestational age (GA), degree of prematurity, severity of neonatal illness, and birth weight are primarily related to eruption of primary teeth.

Artificial Intelligence and Machine Learning for Automated Cephalometric Landmark Identification: A Meta-Analysis Previewed by a Systematic Review.

Digital dentistry has become an integral part of our practice today, with artificial intelligence (AI) playing the predominant role. The present systematic review was intended to detect the accuracy of landmarks identified cephalometrically using machine learning and artificial intelligence and compare the same with the manual tracing (MT) group. According to the PRISMA-DTA guidelines, a scoping evaluation of the articles was performed.