Assessment of Malocclusion and Gender Differences in Orthodontic Treatment Needs Among Adolescents Aged 10-13 Years in Eastern India: A Cross-Sectional Study.

Introduction: Malocclusion is a prevalent public health concern among adolescents, impacting both dental health and psychosocial well-being.

Aims And Objectives: To assess the prevalence of orthodontic treatment needs among adolescents aged 10-13 years in Bhubaneswar using the dental health component (DHC) and aesthetic component (AC) of the Index of Orthodontic Treatment Need (IOTN) and to analyze gender-based differences.

Methodology: A cross-sectional study was conducted among 450 school-going children aged 10-13 years using cluster sampling across Bhubaneswar.

Incidence of postoperative pain after single-visit and multiple-visit root canal therapy: a systematic review.

AIM- The objective of the systematic review is to evaluate the incidence of postoperative pain after single-visit and multiple-visit root canal therapy. METHODS- Published research indexed in PubMed or Scopus or Cochrane or DOAJ or Web of Science evaluating the frequency percentage of postoperative aching after one and several root canal therapy appointments through randomized controlled trials or prospectively were included. RESULT- Most surveys utilized VAS (Visual Analogue Scale) to estimate the degree of pain among the participants.

Efficacy of Submandibular Gland Excision Versus Preservation During Supraomohyoid Neck Dissection for T1, T2, and N0 Oral Squamous Cell Carcinoma.

Introduction: The present study aims to observe the efficacy of submandibular gland excision vs. preservation during supraomohyoid neck dissection (SOHND) based on the postoperative outcomes for early oral squamous cell carcinoma (OSCC) with clinically N0 neck and xerostomia.

Materials And Methods: A pilot study was conducted to observe the efficacy of preservation vs.

Does economic policy uncertainty, nuclear energy, and crude oil influence CO emissions? A sectoral growth analysis on G20 countries.

The G20 nations collectively accounted for a significant portion of global CO emissions due to their vast economies and rising energy demand. While some G20 nations have made substantial efforts to reduce their emissions through policies such as renewable energy incentives and carbon pricing, others may still heavily rely on fossil fuels for energy production and industrial processes. Therefore, this recent study endeavoured to investigate the relationship between nuclear energy consumption (NEC), crude oil (CO), and economic policy uncertainty (EPU) with CO emissions in three economic sectors of G20 nations.

Advancements in framework materials for enhanced energy harvesting.

Energy harvesting, the process of capturing ambient energy from various sources and converting it into usable electrical power, has attracted a lot of attention due to its potential to provide long-term and self-sufficient energy solutions. This comprehensive review thoroughly explores the use of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) for energy harvesting by piezoelectric and triboelectric nanogenerators (PENGs and TENGs). It begins by classifying and outlining the structural diversity of MOFs and COFs, which is key to understanding their importance in energy applications.

From Passive Listeners to Active Learners: Changing Student Preferences in Small Group Learning for the MBBS Curriculum.

The shift toward student-centered learning in medical education has become increasingly apparent in recent years, particularly in small group learning (SGL) within the MBBS curriculum. Traditionally, SGL has been teacher-led, but data from three polls conducted across three MBBS batches (2019, 2022, and 2023) highlight a notable shift in student preferences toward more active learning methods. While the 2019 batch overwhelmingly favored teacher-led explanations, the 2022 and 2023 batches showed a growing preference for self-directed learning, with "Self-reading and Doubt Clearing" becoming the most popular mode by 2023.

Mindfulness as a Path to Freedom from Internet Addiction in Adolescents: A Narrative Review.

In recent years, Internet Addiction Disorder (IAD) has become a major mental health concern among adolescents, with detrimental effects on social relationships, academic performance, and emotional well-being. The focus of mindfulness-based interventions (MBIs) on improving self-awareness, emotional regulation, and cognitive flexibility has drawn interest in MBIs as possible therapeutic approaches for treating IAD. The purpose of this narrative review is to investigate how mindfulness interventions affect teenagers who are experiencing IAD.

Identification and validation of miR-21 key genes in cervical cancer through an integrated bioinformatics approach.

Cervical cancer is one of the most prevalent female reproductive cancers. miR-21 is a multi-target oncomiR that has shown its potential in regulating several cancers including colon, pancreatic, breast, prostate, ovarian, and cervical cancer. However, the signaling network of miR-21 remains underexplored, and only a limited number of miR-21 gene targets in cervical cancer have been reported.

Diagnostic performance of artificial intelligence in detecting oral potentially malignant disorders and oral cancer using medical diagnostic imaging: a systematic review and meta-analysis.

Objective: Oral cancer is a widespread global health problem characterised by high mortality rates, wherein early detection is critical for better survival outcomes and quality of life. While visual examination is the primary method for detecting oral cancer, it may not be practical in remote areas. AI algorithms have shown some promise in detecting cancer from medical images, but their effectiveness in oral cancer detection remains Naïve.

Revitalizing the Smile: A Case Report on the Modified Apexification Procedure for Discolored Non-Vital Immature Teeth With Periapical Lesions.

Apexification is the process of forming mineralized tissue at the apical portion of a tooth with an incompletely formed root. Although various materials and techniques for the endodontic treatment of such teeth have been employed for some time, selecting the appropriate material remains challenging due to limited literature. This report presents a case that evaluates the efficacy of a modified apexification procedure using mineral trioxide aggregate (MTA), followed by a walking-bleach technique to address discoloration resulting from trauma to anterior teeth.

Degradation of Decabromodiphenyl Ether Dispersed in Poly (Acrylo-Butadiene-Styrene) Using a Rotatory Laboratory Pilot Under UV-Visible Irradiation.

The growing volume of plastics derived from electronic waste (e-waste) underscores the imperative for environmentally sustainable strategies for the management of this waste. In light of the paramount importance of this issue, a pilot demonstrator for the decontamination of polymers containing Brominated Flame Retardants (BFRs) has been developed. The objective is to investigate the potential for decontaminating BFR-containing polymers from e-waste via UV-visible irradiation using a rotatory laboratory pilot operating under primary vacuum conditions.

Determining the effect of long non-coding RNA maternally expressed gene 3 (lncRNA MEG3) on the transcriptome profile in cervical cancer cell lines.

This study investigates the role of the long non-coding RNA Maternally Expressed Gene3 (lncRNA MEG3) gene in cervical cancer, as evidenced by its downregulation in cancerous cell lines. The study demonstrates the effects of the overexpression of lncRNA MEG3 in cervical cancer cell lines, particularly in C33A and CaSki. Through comprehensive analyses, including Next-Generation Sequencing (NGS), alterations in global mRNA expression were analyzed.

Comparative Assessment of the Antimicrobial Efficacy of Photoactivated Disinfection Employing Distinct Photosensitizers: A Morphological Analysis Using Scanning Electron Microscopy and Confocal Laser Scanning Microscopy.

Background The complex morphology of the root canal system and bacterial infiltration to greater depths precludes complete debridement by mechanical preparation alone. Despite promising characteristics of photodynamic inactivation (PDI) and different photosensitizers (PSs), there has been limited research on the antibacterial efficacy of chitosan (CS)-based PS combinations for root canal disinfection. We aimed to evaluate and compare the antimicrobial efficacy of photoactivated disinfection (PAD) using two different PSs as an adjunct to final irrigation in root canal treatment.

PIM1 kinase and its diverse substrate in solid tumors.

The PIM kinase family, consisting of PIM1, PIM2, and PIM3, is a group of serine/threonine protein kinases crucial for cellular growth, immunoregulation, and oncogenesis. PIM1 kinase is often overexpressed in solid and hematopoietic malignancies, promoting cell survival, proliferation, migration, and senescence by activating key genes. In vitro and in vivo studies have established the oncogenic potential of PIM1 kinases.

Involvement of E3 Ubiquitin Ligases in Viral Infections of the Human Host.

Viral infections are one of the principal causes of global primary health crises, with increased rate of infection and mortality demonstrated by the newer progeny of viruses. Viral invasion of the host involves utilization of various cellular machinery. Ubiquitination is one of a few central regulatory systems used by viruses for establishment of the infections in the host.

Mental health issues and the association of mental health literacy among adolescents in urban Ethiopia.

Background: Epidemiological evidence about the prevalence of adolescent mental health issues and their association with mental health literacy is crucial for sustained mental health promotion strategies. Adolescence is a critical life stage for mental health promotion. However, evidence is not available among Ethiopian school adolescents.

Safe Food Coloring Agent as an Alternative to Eosin Stain.

Introduction Eosin stain is a commonly used histological dye that selectively binds to acidic structures in cells, imparting a color between pink and red. Eosin stain can be harmful due to its chemical composition. Inhaling eosin stain in powder form or as aerosolized droplets can cause irritation in the respiratory tract.

Changes in Smoking Patterns in Turkey Before and After the Ban on Loose Cigarettes: An Ecological Perspective From Global Tobacco Surveillance Data.

Introduction: Loose or individual cigarettes sold without packaging pose a unique challenge for tobacco control, which is the leading cause of premature and preventable mortality worldwide. This study aims to assess the changes in smoking patterns following the ban on loose cigarettes in 2008 in Turkey.

Method: Gender-stratified trend analysis of smoking patterns before and after the ban on loose cigarettes was done using the Global Tobacco Surveillance data (adults: Global Adult Tobacco Survey (GATS) 2008, 2012, and 2016; youth: Global Youth Tobacco Survey (GYTS) 2003, 2005, 2009, 2012, and 2017) from Turkey.

Assessment of Patient Satisfaction and Oral Health-Related Quality of Life Following Full Mouth Rehabilitation with Implant-Supported Prostheses.

Background: The concept of success is typically established by the researcher or the practitioner rather than the patient, who has the greatest stake in the outcome of the prosthodontics therapy.

Aim: To assess patient satisfaction and oral health-related quality of life (OHRQoL) in following full mouth rehabilitation with implant-supported prostheses (ISP).

Methods And Materials: Thirty-two patients who underwent full mouth rehabilitation with ISP were included in this study.

Analysis of Long-Term Success and Biological Complications in Zygomatic Implant-Supported Prostheses.

Introduction: Patients with significant maxillary atrophy who are not candidates for standard implants now have an option thanks to zygomatic implants. Long-term statistics on difficulties and success are, however, scarce.

Methods: A tertiary care center's patient data were retrospectively analyzed.

Evaluation of Treatment Outcomes and Quality of Life in Patients with Obstructive Sleep Apnea Receiving Oral Appliance Therapy.

Background: A frequent sleep condition linked to considerable morbidity and death is obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) therapy is not the only noninvasive treatment option for OSA. Another option is oral appliance therapy (OAT).

Assessment of Oral Health Promotion Programs in Schools and their Long-Term Effects.

Background: School-based oral health promotion initiatives are essential for enhancing children's and teenagers' oral health outcomes. However, the long-term efficacy of these initiatives is yet unknown.

Methods: Over the course of a year, 500 children between the ages of 6 and 12 years participated in prospective observational research.