352 results match your criteria: "Kabul University of Medical Sciences[Affiliation]"

Nasal rehabilitation following basal cell carcinoma (BCC) and radiotherapy presents significant challenges due to the intricate balance between aesthetic and functional restoration. This case report discusses the rehabilitation of a 73-year-old male who underwent surgical excision and radiotherapy for BCC located on the left ala of the nose. Post-treatment, the patient experienced dissatisfaction with his facial appearance, negatively impacting his quality of life.

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Introduction: Ranulas are mucous cysts that arise from the sublingual gland due to ductal obstruction or trauma. Plunging ranulas, a rare variant, extend into the neck and often present diagnostic challenges. Definitive surgical management is necessary to prevent recurrence and ensure successful outcomes.

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Anti-seizure medications (ASMs) are specific types of anticonvulsants used to treat epileptic seizures. However, several studies have shown an association between ASMs and an increased risk of hematological disorders, such as thrombocytopenia, aplastic anemia, and platelet function disorders leading to prolonged bleeding times. This review explores the existing literature on this topic, investigating a wide variety of ASMs, ranging from first-generation medications to newer ones.

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Anastomotic leaks (ALs) remain a serious postoperative complication in colorectal surgery, often resulting in significant morbidity, prolonged hospitalization, and increased mortality risk. This systematic review aims to evaluate the role of predictive biomarkers in the early detection of ALs, focusing on their diagnostic accuracy and clinical utility. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive literature search was conducted across MEDLINE, Scopus, CENTRAL, and Web of Science, identifying studies that examined biomarkers such as C-reactive protein (CRP), procalcitonin (PCT), and white blood cell (WBC) count in the context of AL.

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Article Synopsis
  • Complete agenesis of the pancreas is life-threatening, but partial agenesis of the dorsal pancreas is less severe and linked to abnormal development; its causes are still unclear.
  • A 60-year-old woman's abdominal CT revealed partial agenesis of the dorsal pancreas alongside signs of chronic pancreatitis, with no other complications noted.
  • Advances in imaging techniques have increased awareness and diagnosis of partial dorsal pancreas agenesis, and while treatment isn’t required alone, annual check-ups are advised due to potential cancer risk in the ventral pancreas.
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Mapping the global neurosurgery workforce. Part 2: Trainee density.

J Neurosurg

July 2024

2Department of Global Health and Social Medicine, Program for Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts.

Article Synopsis
  • The study aimed to analyze the global neurosurgery training workforce, focusing on the types of training programs, trainee support, diversity of experiences, and accreditation processes.
  • Data were collected from 187 countries and 25 territories, revealing an estimated 1,261 training programs and over 10,500 trainees, with significant variations in density based on country income levels and WHO regions.
  • High-income countries had a much higher density of trainees (0.48 per 100,000 people) compared to lower-income countries, which faced challenges like limited subspecialty training and resources.
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Mapping the global neurosurgery workforce. Part 1: Consultant neurosurgeon density.

J Neurosurg

July 2024

2Department of Global Health and Social Medicine, Program for Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts.

Article Synopsis
  • The study aimed to assess the global distribution and growth of consultant neurosurgeons, especially in low- and middle-income countries, to understand the impact of efforts to expand access to neurosurgery worldwide.
  • A comprehensive electronic survey was conducted across 192 countries and 25 territories, revealing an estimated 72,967 neurosurgeons, with a global density of 0.93 per 100,000 people, and significant variation by income level.
  • Findings indicated that neurosurgeon density increases with national income level, highlighting the shortage in low-income areas, particularly in WHO African and Southeast Asia regions, while the Western Pacific region showed the highest density of neurosurgeons.
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Background: Tuberculosis (TB) remains a major public health concern in Pakistan, which is ranked fifth among high-burden TB nations worldwide. The growing frequency of drug-resistant TB strains, particularly multidrug-resistant TB (MDR-TB), creates new obstacles. Socioeconomic factors, a lack of awareness, and inadequate healthcare infrastructure all contribute to the spread of the disease.

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Background: Hearing loss (HL) is a major public health problem that is significant for mental health and physical conditions. HL may be a potentially modifiable risk factor for poorer mental health outcomes. The study aimed to explore the association between HL, social isolation, anxiety, and depression.

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Hydatid cyst is a zoonotic disease rarely involving the adrenal glands, even in areas where the disease is endemic. The purpose of this article is to present the clinical and imaging findings of adrenal hydatid cysts, along with a comprehensive literature review of related research. Here we report a rare case of an 18-year-old male with a right adrenal cystic lesion showing characteristic features of a hydatid cyst on ultrasonography and computed tomography, which turned out to be an adrenal hydatid cyst after surgical excision.

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Background: Oral cancer (OC) is a major global health issue, with tobacco use being one of the most significant preventable risk factors. Despite its strong association with OC, public awareness about the harmful effects of tobacco remains limited. This study aims to evaluate the awareness and knowledge of tobacco use related to oral cancer among patients referred to the Stomatology Teaching Hospital.

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Hereditary gingival fibromatosis (HGF) is an uncommon genetic condition marked by gradual and progressive overgrowth of fibrous tissue in the gums, which is benign in nature. It is a genetic disorder inherited in an autosomal dominant pattern, known for its considerable genetic diversity. The marginal, attached, and interdental gingivae are affected by this condition.

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Background: Dental caries is a major, multifactorial oral condition that causes the demineralization of tooth enamel and impacts approximately half of the world's child population. This study aimed to determine the prevalence of dental caries among school-going children aged 7 to 13 years in Kabul city.

Methods: This descriptive cross-sectional study was conducted with 491 students aged 7 to 13 years in Kabul during the first half of 2019.

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Nomophobia (no-mobile-phone phobia) is the fear and anxiety of being without a mobile phone. This study pioneers the investigation of nomophobia in Afghanistan using the Nomophobia Questionnaire (NMP-Q), addressing a crucial gap in the field. We collected statistical data from 754 undergraduate medical students, comprising men (56.

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Article Synopsis
  • This systematic review evaluates the feasibility and safety of early oral feeding (EOF) after radical gastrectomy in gastric cancer patients, analyzing eight studies from 2011 to 2020.
  • Most patients began oral feeding within 72 hours post-surgery with high adherence rates, showing EOF to be generally well-tolerated and associated with comparable or lower postoperative complications than traditional feeding methods.
  • Despite potential benefits like shorter hospital stays and improved nutritional status, results varied, highlighting the need for individualized patient approaches and calling for larger trials to develop standardized EOF protocols.
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With the COVID-19 pandemic, behavioural scientists aimed to illuminate reasons why people comply with (or not) large-scale cooperative activities. Here we investigated the motives that underlie support for COVID-19 preventive behaviours in a sample of 12,758 individuals from 34 countries. We hypothesized that the associations of empathic prosocial concern and fear of disease with support towards preventive COVID-19 behaviours would be moderated by trust in the government.

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Article Synopsis
  • Non-alcoholic steatohepatitis (NASH) is a serious illness with limited treatment options, and the FDA has recently approved resmetirom, a drug targeting the thyroid hormone receptor, for its treatment.
  • In a review of four randomized controlled trials, resmetirom notably improved MRI-proton density fat fraction, reduced liver fat by 30%, and resolved NASH without fibrosis, although effects on certain liver enzymes were mixed.
  • Resmetirom was linked to significant drops in various lipid levels (like triglycerides and LDL), but it also increased the likelihood of side effects such as diarrhea and nausea in patients.
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Intra-abdominal retroperitoneal fetus in fetu: A case report.

Radiol Case Rep

November 2024

Radiology Department, French Medical Institute for Mothers and Children (FMIC), Kabul University of Medical Sciences (KUMS), Kabul, Afghanistan.

Fetus in fetu (FIF) is a rare abnormality where a vertebrate parasitic fetus develops inside the body of another normally developing fetus. It is distinct from teratomas, tumors composed of cells from multiple germ layers and have malignant potential. Symptoms of FIF arise from the mass effect, causing abdominal distension, feeding difficulties, and pressure effects on organs.

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Factors associated with postnatal care utilization in Afghanistan.

BMC Womens Health

August 2024

Department of Behavioral Sciences and Health Education in, Kabul University of Medical Sciences "Abu Ali Ibn Sina", Jamal Mina 3rd District, Kabul City, Afghanistan.

Afghanistan has one of the highest maternal mortality rates in the world. Inadequate postnatal care (PNC) increases the risk of maternal mortality. This study aimed to analyze the socioeconomic and demographic factors that affect postnatal care utilization.

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Over 20% of ischemic strokes are cardioembolic strokes, necessitating research into thrombus formation locations, particularly the left atrial appendage (LAA). The left atrial septal pouch (LASP), which is linked to thrombus development and stasis, has drawn attention recently as a possible thromboembolic location, especially in atrial fibrillation (AF). The primary aim of this review is to explore LASP's role in cryptogenic strokes and to discuss the methods used to assess LAA anatomy.

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Background: The optimal treatment regimen for patients with cancer-associated venous thromboembolism (CA-VTE) remains unclear. Therefore, the authors sought to compare the outcomes of (VKAs) versus direct apixaban and low molecular weight heparin (LMWH) in patients with CA-VTE.

Methods: MEDLINE, Embase, and Cochrane Central databases were searched for randomized controlled trials (RCTs) and observational studies comparing the efficacy and safety of apixaban and LMWH in patients with CA-VTE.

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Background: The rapid growth of social media has profoundly transformed communication, community building, and information sharing worldwide. In Afghanistan, the proliferation of social media platforms has significantly impacted the social, cultural, and political landscape, particularly among the youth.

Objective: This multi-disciplinary study aims to explore the diverse effects of social media on Afghan youth, focusing on usage patterns, mental health implications, entertainment-driven time allocation, financial expenditures, exposure to explicit content, and academic performance.

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Background: Low- and middle-income countries (LMICs) face high burden of common mental disorders (CMDs). Most of the evidence for the Collaborative Care (CC) model effectiveness comes from high-income countries (HICs) and may not generalise to LMICs. A systematic review was conducted to assess effectiveness of CC for CMDs in LMICs.

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Background And Aims: Since 1990, global child and infant mortality rates have typically stabilized or decreased due to improved healthcare, vaccination rollouts, and international funding. However, Afghanistan continues to face the highest child and infant mortality rates globally, with 43 deaths per 1000 live births. This study aims to examine the factors contributing to this high mortality rate and propose interventions to address the issue.

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