19 results match your criteria: "KU Leuven - Leuven University[Affiliation]"

Freshwater ecosystems are highly biodiverse and important for livelihoods and economic development, but are under substantial stress. To date, comprehensive global assessments of extinction risk have not included any speciose groups primarily living in freshwaters. Consequently, data from predominantly terrestrial tetrapods are used to guide environmental policy and conservation prioritization, whereas recent proposals for target setting in freshwaters use abiotic factors.

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Article Synopsis
  • Scientists are looking for better ways to grow eggs from ovarian tissue in the lab.
  • They tried using a new method called a "perifusion bioreactor," which moves fluids, instead of just keeping the tissue still.
  • This new method helped improve the health and quality of the follicles (the tiny sacs that hold the eggs) in both cows and humans!
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The recent spreading of African swine fever (ASF) over the Eurasian continent has been acknowledged as a serious economic threat for the pork industry. Consequently, an extensive body of research focuses on the epidemiology and control of ASF. Nevertheless, little information is available on the combined effect of ASF and ASF-related control measures on wild boar () population abundances.

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Unraveling the Role of Empathy and Critical Life Events as Triggers for Social Entrepreneurship.

Front Psychol

November 2020

Department of Marketing and Supply Chain Management, Faculty of Management, Open Universiteit, Heerlen, Netherlands.

Social entrepreneurs are generally believed to have started their venture to improve societal needs and create social value. Yet, in order to achieve continuity of their organization, they need to generate economic value as well. These seemingly opposite objectives of social and economic value creation can cause tensions in social enterprises.

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The transition to solid-state Li-ion batteries will enable progress toward energy densities of 1000 W·hour/liter and beyond. Composites of a mesoporous oxide matrix filled with nonvolatile ionic liquid electrolyte fillers have been explored as a solid electrolyte option. However, the simple confinement of electrolyte solutions inside nanometer-sized pores leads to lower ion conductivity as viscosity increases.

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Multi-factorial age estimation: A Bayesian approach combining dental and skeletal magnetic resonance imaging.

Forensic Sci Int

January 2020

Department of Imaging and Pathology - Forensic Odontology, KU Leuven, Kapucijnenvoer 7 blok a bus 7001, 3000 Leuven, Belgium. Electronic address:

Purpose: To study age estimation performance of combined magnetic resonance imaging (MRI) data of all four third molars, the left wrist and both clavicles in a reference population of females and males. To study the value of adding anthropometric and sexual maturation data.

Materials And Methods: Three Tesla MRI of the three anatomical sites was prospectively conducted from March 2012 to May 2017 in 14- to 26-year-old healthy Caucasian volunteers (160 females, 138 males).

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Background: MRI of the clavicle's sternal end has been studied for age estimation. Several pitfalls have been noted, but how they affect age estimation performance remains unclear.

Purpose/hypothesis: To further study these pitfalls and to make suggestions for a proper use of clavicle MRI for forensic age estimation.

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Background: 22q11.2 deletion syndrome (22q11DS) is a genetic disorder associated with neurodevelopmental, anxiety and mood disorders, as well as an increased risk for developing psychosis. Cortisol levels and stress reactivity reflect hypothalamic-pituitary-adrenal (HPA)-axis activity, and are believed to be altered in individuals that often experience daily-life stress, depression, and psychotic symptoms.

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Background: The 22q11.2 deletion syndrome (22q11DS) is caused by a deletion on chromosome 22 locus q11.2.

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  • There's been a lot of new research on tiny structures called extracellular vesicles (EVs) that cells release, which help us understand how cells work and what goes wrong in diseases.
  • Scientists have had a hard time studying these EVs because they come in different types and can be tough to separate and analyze properly.
  • The International Society for Extracellular Vesicles updated their guidelines, called MISEV2018, to help researchers share clear information about how to study EVs and ensure their findings are accurate and reliable.
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Emerging evidence shows that stress can impair the ability to learn from and pursue rewards, which in turn has been linked to motivational impairments characteristic of the psychotic disorder. Ventral striatal dopaminergic neurotransmission has been found to modulate reward processing, and appears to be disrupted by exposure to stress. We investigated the hypothesis that stress experienced in the everyday life has a blunting effect on reward-induced dopamine release in the ventral striatum of 16 individuals at a familial risk for psychosis compared to 16 matched control subjects.

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Social anhedonia and asociality in psychosis revisited. An experience sampling study.

Psychiatry Res

December 2018

Center for Contextual psychiatry, Department of Neurosciences, KU Leuven- Leuven University, Leuven, Belgium.

The DSM-5 appended the conceptualization of asociality in psychotic disorders as the manifestation of diminished interest in social interactions, but it also admitted that it might merely be the result of limited opportunities for social interactions. In an effort to investigate this apparent dichotomy, we used experience sampling data from 149 patients with psychotic disorder and 143 controls, and divided their social interactions into those occurring in the context of work and other structured activities that patients have limited access to, and those occurring in the context of unstructured activities such as visits and conversations that both groups can choose relatively more freely. Patients spent significantly smaller proportion of their time in structured social context, but matched the controls in the time spent in unstructured social contexts, and endorsed intact hedonic experience of both social contexts.

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Psychosis as a Dialectic of Aha- and Anti-Aha-Experiences.

Schizophr Bull

September 2019

Center for Contextual Psychiatry, Department of Neurosciences, KU Leuven - Leuven University, Leuven, Belgium.

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22q11.2 deletion syndrome (22q11DS) is a genetic disorder caused by a microdeletion on chromosome 22q11.2 and associated with an increased risk for developing psychosis.

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Background: Abnormalities in reward learning in psychotic disorders have been proposed to be linked to dysregulated subcortical dopaminergic (DA) neurotransmission, which in turn is a suspected mechanism for predisposition to psychosis. We therefore explored the striatal dopaminergic modulation of reward processing and its behavioral correlates in individuals at familial risk for psychosis.

Methods: We performed a DA D2/3 receptor [18F]fallypride positron emission tomography scan during a probabilistic reinforcement learning task in 16 healthy first-degree relatives of patients with psychosis and 16 healthy volunteers, followed by a 6-day ecological momentary assessment study capturing reward-oriented behavior in the everyday life.

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Much human behavior is driven by rewards. Preclinical neurophysiological and clinical positron emission tomography (PET) studies have implicated striatal phasic dopamine (DA) release as a primary modulator of reward processing. However, the relationship between experimental reward-induced striatal DA release and responsiveness to naturalistic rewards, and therefore functional relevance of these findings, has been elusive.

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Background: Separate transmission networks for human immunodeficiency virus (HIV) coexist. Molecular typing of viral genomes can provide insight in HIV transmission routes in donors for whom risk behavior-based donor selection failed.

Study Design And Methods: This study includes all HIV-infected Dutch and Flemish donors in the period 2005 to 2014 (n = 55).

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The hubris hypothesis: The downside of comparative optimism displays.

Conscious Cogn

April 2017

Centre for Research on Self and Identity, Psychology Department, University of Southampton, Southampton S017 1BJ, UK. Electronic address:

According to the hubris hypothesis, observers respond more unfavorably to individuals who express their positive self-views comparatively than to those who express their positive self-views non-comparatively, because observers infer that the former hold a more disparaging view of others and particularly of observers. Two experiments extended the hubris hypothesis in the domain of optimism. Observers attributed less warmth (but not less competence) to, and showed less interest in affiliating with, an individual displaying comparative optimism (the belief that one's future will be better than others' future) than with an individual displaying absolute optimism (the belief that one's future will be good).

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Microbiome-based companion diagnostics: no longer science fiction?

Gut

June 2016

Department of Microbiology and Immunology, Rega Institute, KU Leuven-Leuven University, Leuven, Belgium VIB Center for the Biology of Disease, Leuven, Belgium.

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