2 results match your criteria: "KRIBB BVC Center 109[Affiliation]"

Long-term acclimation to organic carbon enhances the production of loliolide from Scenedesmus deserticola.

Bioresour Technol

November 2024

Cell Factory Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea; Department of Environmental Biotechnology, KRIBB School of Biotechnology, University of Science & Technology (UST), Daejeon 34113, Republic of Korea; ASK LABS, KRIBB BVC Center 109, Daejeon 34141, Republic of Korea. Electronic address:

Article Synopsis
  • The study focuses on enhancing the productivity of Scenedesmus deserticola for commercial production of loliolide through long-term acclimation using glucose as an organic carbon source.
  • After a year of acclimation, a specific strain (S. deserticola HS4) showed at least a 2-fold increase in loliolide production and underwent further testing in larger cultivation setups.
  • The findings indicate that long-term acclimation can significantly improve the productivity and adaptability of microalgae, making them more viable for industrial applications.
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Herein, different extracts of JD052, a green microalga, were evaluated in vitro as a potential anti-aging bioagent. Although post-treatment of microalgal culture with either UV irradiation or high light illumination did not lead to a substantial difference in the effectiveness of microalgal extracts as a potential anti-UV agent, the results indicated the presence of a highly potent compound in ethyl acetate extract with more than 20% increase in the cellular viability of normal human dermal fibroblasts (nHDFs) compared with the negative control amended with DMSO. The subsequent fractionation of the ethyl acetate extract led to two bioactive fractions with high anti-UV property; one of the fractions was further separated down to a single compound.

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