Functional Outcomes in the Distal End of Radius Fracture: A Prospective Study in a Tertiary Care Center.

Objectives: The objectives of this study are to determine the functional outcomes and compare them between conservative and surgical management in patients managed for closed-type intra-articular distal end of radius fractures.

Methods: A prospective observational study was done on 150 patients who underwent treatment for closed-type intra-articular distal end of radius fractures. As per Frykman Classification, they were type III.

A case report on asymptomatic ventricular hemangioma.

Intraventricular cardiac hemangiomas are very rare tumors that account for 5-10% of all cardiac tumors. We report a case of an asymptomatic 21-year-old young male who was incidentally detected with ventricular mass on echocardiography followed by magnetic resonance imaging. Surgical resection was done for confirmation and to avoid potential complications.

Neck extensor myopathy- a treatable cause of dropped head syndrome.

Dropped head syndrome (DHS) is characterized by a passively correctable chin-on-neck deformity inerect posture and can stem from a wide variety of neurological disorders spanning the neuraxis. Neuromuscular disorders account for a major chunk of DHS and include disease of anterior horn celldiseases, polyradiculopathies and cervical plexopathies, disease of neuromuscular junction andmyopathies. Isolated DHS without additional neurological features poses a management challenge, particularly because the symptoms can signifi cantly impact the patient's quality of life and may notalways respond to treatment.

In vitro cancer cell line luminescence-based validation of anticancer phytocompounds obtained from Leucas biflora against HELA cervical and A549 lung cancer cells.

Current research aims to screen the anticancer prospective of Leucas biflora phytocompounds against apoptotic regulator target protein essential for cancer progression. In gas chromatography-mass spectrometry analysis major phytocompounds such as tetracosahexaene, squalene, phytol, 22-stigmasten-3-one, stigmasterol, fluorene, and 1,4-dihydro were identified in ethanolic leaf extract of Leucas biflora. In vitro, the free radical scavenging potential of ethanolic leaf extract of Leucas biflora was examined through its DPPH and ABTS radical scavenging potential IC value 15.

Congenital Rare Abnormal Shapes of Lungs in Relation to Abnormal Lobes and Fissures and Its Clinical Implications.

Background: Detailed anatomical knowledge of congenital abnormalities of the lungs is essential for proper evaluation and treatment of respiratory diseases, identification of bronchopulmonary segments during lobectomies and surgical resection, and identification and interpretation of their variable radiological imaging.

Aim: Accordingly, the aim of this study was designed to evaluate the prevalence of congenital abnormal shapes of lungs in relation to abnormal lobes and fissures.

Materials And Methods: This study was carried out on 270 isolated lung specimens (right lungs - 135 and left lungs - 135) from 135 formalin-embalmed middle-aged human cadavers irrespective of gender.

Temporal Trends in SARS-CoV-2 Antibody Levels Among COVID-19 Patients in Kerala During the First Wave and Pre-vaccination Period.

Background: The SARS-CoV-2 virus interacts with host cells through the S1 domain of its spike protein. This study measures the IgG immune response to this domain in COVID-19 patients from Kerala, India, and explores its association with various health factors.

Methods: A cohort of 258 COVID-19 patients was analyzed for IgG antibodies targeting the S1 spike protein domain.

Cardiovascular Risk Factors and Metabolic Syndrome among Police Officers in Kozhikode Corporation.

Context: Police personnel constitute a special occupational group with exposure to stressful work environment indirectly resulting in a high prevalence of cardiovascular risk factors, including metabolic syndrome (MS), hypertension, hyperlipidemia, cigarette smoking, and a sedentary lifestyle is reported among policemen. Surveillance activities are limited in the present scenario.

Aims: The present study was designed to measure the prevalence of metabolic syndrome and other cardiovascular risk factors among police officers in Kozhikode district and observe the trend over the last 10 years.

Medication Adherence in Cancer Patients: A Comprehensive Review.

Cancer is a complex disease that can affect different parts of the body. The rates of cancer have shown an increasing trend in the past decade. A majority of cancers are detected late, therefore becoming untreatable and resulting in significant mortality.

Workplace Violence Faced by Medical Doctors in Kerala, India.

Introduction: The escalation of violence against doctors, a global concern, is also evident in India. In recent years, there has been a noticeable increase in the instances of violence against doctors in Kerala, a state situated in the southern part of India. This study examines the prevalence and types of violence against doctors in Kerala, considering factors, such as gender, workplace, designation, timing, and those involved.

Knowledge, Attitude and Experiences of Students Regarding Menstrual Cup Usage in a Medical College in North Kerala, India.

Background: Sanitary napkins form a major source of solid waste, the disposal of which often results in environmental pollution. Menstrual cups are an eco-friendly and cost-effective alternative to sanitary pads that have yet to gain much popularity among Indian women. The current study aims to assess the knowledge, attitude, and experiences of using the menstrual cup among medical students in a college in north Kerala, India.

Symptomatology and Demographic Profile of COVID-19 Patients Admitted to a Tertiary Care Center in India: A Hospital Record-Based Study.

Introduction: Since its arrival in late 2019, COVID-19 has caused more than 760 million cases and nearly seven million deaths worldwide. As a novel infection research is still underway to understand the epidemiology of COVID-19. The present study was conducted in a tertiary care center in south India to understand the symptomatology of the disease in a local context.

Accessory heads of biceps brachii muscle its embryogenesis and clinical implications: Cadaveric study.

Background: Biceps brachii is an elongated two-headed fusiform muscle of the anterior compartment of the arm which crosses the shoulder as well as the elbow joint. It assists in flexion of the shoulder joint and elbow joint and powerful supinator of the forearm. It also assists in the abduction of the shoulder joint.

Role Play versus Small Group Discussion in Teaching Prescription Communication Skills: A Comparative Study on students of Phase Two of the Bachelor of Medicine and Bachelor of Surgery (MBBS) Course.

Introduction: Inadequate prescription communication skills of the medical graduates lead to poor therapeutic outcome and increased burden on the healthcare system. This gap has to be addressed through effective methods for teaching prescription communication skills to medical students. This study compared the effectiveness of Role play and Small Group Discussion (SGD) in teaching prescription communication skills to students of Phase Two of the Bachelor of Medicine and Bachelor of Surgery (MBBS) course.

Nurses as Warriors: Challenges and Impacts among Kerala Nurses during Coronavirus Disease-2019 Pandemic.

Introduction: In December 2019, the global outbreak of coronavirus disease-2019 (COVID-19) was announced. The pandemic has cast a spotlight like never before on health-care professionals in general, and nurses in particular. Nurses have been dubbed "warriors" by the general public for their determination to provide frontline care to patients with the disease, despite the risk of exposure and a lack of professional resources.

Prevalence of anaemia and associated factors among antenatal women in rural Kozhikode, Kerala.

Context: Anemia in pregnancy is a significant public health concern with detrimental aftereffects on maternal and fetal well-being universally, especially in developing countries like India.

Aims: To estimate the prevalence of anemia in pregnant women in rural areas of Kozhikode by hemoglobin estimation and to study the selected factors associated with anemia.

Settings And Design: A cross-sectional study was conducted among 295 antenatal women in all three trimesters residing in six selected panchayats of Kozhikode district from July 2016 to March 2017.

Emotional Self-Care: Exploring the Influencing Factors Among Individuals With Cancer.

Cancer is a leading source of distress and fatality worldwide. Cancer-related aberrant cell proliferation causes excruciating pain and impairment. To cope with pain and manage symptoms and illness, pharmaceutical and non-pharmacological options are available.

Burden of osteoarthritis in India and its states, 1990-2019: findings from the Global Burden of disease study 2019.

Objective: To describe the burden of osteoarthritis (OA) in India from 1990 to 2019.

Design: Data from Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 were used. The burden of OA -knee OA, hip OA, hand OA, and other OA- was estimated for India and its states from 1990 to 2019 through a systematic analysis of prevalence, incidence, years lived with disability (YLD), and disability-adjusted life years (DALY) using methods reported in GBD 2019 study.

30-Day and 1-Year Outcomes With HYDRA Self-Expanding Transcatheter Aortic Valve: The Hydra CE Study.

Objectives: This study sought to evaluate the 30-day and 1-year safety and performance of the Hydra transcatheter aortic valve (THV) (in the treatment of symptomatic severe aortic stenosis in patients at high or extreme surgical risk.

Background: The Hydra THV is a novel repositionable self-expanding system with supra-annular bovine pericardial leaflets.

Methods: The Hydra CE study was a premarket, prospective, multicenter, single-arm study conducted across 18 study centers in Europe and Asia-Pacific countries.

A Cross-Sectional Study of Nailfold Capillary Changes in Psoriasis.

Background: Microcirculation in the skin of psoriasis patients significantly differs from unaffected individuals. Vascular changes precede skin lesions and occur even in nonlesional skin.

Aims: The primary aim of this work was to study the nailfold capillary changes in psoriasis patients, and to compare it with that of controls.

2021 Asia-Pacific League of Associations for Rheumatology clinical practice guideline for treatment of gout.

Background: Gout is the most prevalent inflammatory arthritis in the Asia-Pacific region and worldwide. This clinical practice guideline (CPG) aims to provide recommendations based on systematically obtained evidence and values and preferences tailored to the unique needs of patients with gout and hyperuricemia in Asia, Australasia, and the Middle East. The target users of these guidelines are general practitioners and specialists, including rheumatologists, in these regions.

All India Difficult Airway Association guidelines in practice-A survey.

Background And Aims: The All India Difficult Airway Association (AIDAA) has come up with difficult airway (DA) guidelines to suit the Indian context. We conducted an online survey with the primary aim to find out the awareness about AIDAA guidelines and adherence to them in clinical practice. The secondary aims were to explore variations in practice with respect to experience or the type of the institute.

Clinical evaluation of the Hydra self-expanding transcatheter aortic valve: 6 month results from the GENESIS trial.

Objectives: To evaluate the safety and performance of the Hydra transcatheter aortic valve (THV) in the treatment of symptomatic severe aortic stenosis in patients at high or extreme surgical risk.

Background: The Hydra THV (Vascular Innovations Co. Ltd.