Assessment of Oral Health Promotion Programs in Schools and their Long-Term Effects.

Background: School-based oral health promotion initiatives are essential for enhancing children's and teenagers' oral health outcomes. However, the long-term efficacy of these initiatives is yet unknown.

Methods: Over the course of a year, 500 children between the ages of 6 and 12 years participated in prospective observational research.

Clinical Evaluation of Role of Laser in Soft Tissue Surgical Guide for Implant Placement.

Background: Applying automated laser ablation procedures with pulsed, electronically administered diode laser equipment, and large-area masking results in highly aligned, uniform microstructures on these surfaces.

Aim: Clinical evaluation of role of laser in soft tissue surgical guide for implant placement.

Methods And Materials: This study included 30 patients with dental implants in their oral cavity.

Evaluation of Implant Stability Quotient of Sandblasted Acid-Etched (SAE) and Chemical-Modified SAE Dental Implants: A Clinical Study.

Objectives: The goal of the current research was to assess the implant stability quotient (ISQ) of dental implants that were chemically changed with SAE and without SAE.

Materials And Methods: Patients in the current study had dental implants fitted with SAE (Group I) and chemically altered SAE (Group II). After implant implantation, resonance frequency analysis (RFA) was performed as soon as possible as well as one, three, six, nine, and twelve weeks later.

Epidemiological Study of Oral Cancer Cases Over a 10-Year Period.

Background: Because it causes high rates of morbidity and death, oral cancer represents a major global public health concern. It is vital to comprehend the epidemiological trends of oral cancer instances to execute efficacious preventive and therapy tactics.

Objectives: The objective of this retrospective study was to examine the epidemiological patterns of cases of oral cancer in a tertiary care environment over a period of 10 years.

Factors Influencing the Success of Endodontic Retreatment: Insights from a Retrospective Study.

Objective: The purpose of this retrospective study was to assess the variables affecting endodontic retreatment technique success.

Methods: A 5-year period of 500 patient records from a dental clinic were examined. Pre-operative factors, procedure specifics, post-operative results, and demographic information were all documented.

Evaluation of Post-Operative Pain Management Techniques in Oral Surgery.

Objective: This prospective research directed to estimate the efficacy and safety of different post-operative pain management techniques in oral surgery subjects.

Methods: Patients scheduled for various oral surgical procedures were recruited from a single oral surgery clinic between January 2022 and December 2023. Inclusion criteria encompassed adult subjects undergoing elective oral surgery under local or general anesthesia.

Emissive Lipid Nanoparticles as Biophotonic Contrast Agent for Site-Selective Solid Tumor Imaging in Pre-Clinical Models.

Small organic dye-based fluorescent agents are highly potent in solid tumor imaging but face challenges such as poor photostability, nonspecific distribution, low circulation, and weak tumor binding. Nanocarriers overcome these issues with better physicochemical and biological performance, particularly in cancer imaging. Among the various nanosized carriers, lipid formulations are clinically approved but yet to be designed as bright nanocontrast agents for solid tumor diagnosis without affecting surrounding tissues.

Unveiling bisphenol A toxicity: human health impacts and sustainable treatment strategies.

Introduction: The widespread presence of bisphenol-A (BPA) in consumer goods like water bottles and eyeglass frames raises serious concerns about the chemical's ability to accumulate in human tissues. Molecular filtration and activated carbon adsorption are two of the many BPA treatment technologies that have emerged in response to these issues; both are essential in the removal or degradation of BPA from water sources and industrial effluents.

Content: To secure the long-term health and environmental advantages of BPA treatment approaches, sustainable development is essential.

Effect of silver diamine fluoride and potassium iodide on shear bond strength for glass ionomer cement to primary dentine.

Silver diamine fluoride (SDF) is a highly effective topical fluoride for halting dental caries; however, it darkens both teeth and restorations. Therefore, it is of interest to assess the shear bond strength (SBS) of glass ionomer cement (GIC) to caries-affected dentin treated with SDF alone and SDF followed by KI. Forty primary molar samples were prepared to reveal a flat dentin surface and were randomly assigned to two groups.

Correlation of Leptin Concentration in Gingival Crevicular Fluid on the Rate of Orthodontic Tooth Movement - A Prospective Study.

Background: The evaluation of genetic markers in the gingival crevicular fluid (GCF) and their connection to tooth movement can be helpful.

Aim: The objective of this research is to assess the relationship involving leptin levels and orthodontic tooth movement (OTM).

Study Setting And Design: Thirty individuals reporting to the Department of Orthodontics participated in an observational prospective study.

Prognostic significance of anatomic site-specific depth of invasion in oral squamous cell carcinoma - An eastern Indian multi-center study.

A crucial parameter in determining the prognosis of oral cavity cancer is depth of invasion (DOI). This research aimed to correlate pathological DOI at different intra-oral anatomical sites for oral squamous cell carcinoma (OSCC) with the risk of regional lymph node metastasis (LNM). This study also investigated the correlation of 3-year overall survival (OS) and disease-specific survival (DSS) with tumor depth.

Engineered PLGA Core-Lipid Shell Hybrid Nanocarriers Improve the Efficacy and Safety of Irinotecan to Combat Colon Cancer.

Poly(lactide--glycolide) (PLGA) is a biocompatible and biodegradable copolymer that has gained high acceptance in biomedical applications. In the present study, PLGA ( = 13,900) was synthesized by ring-opening polymerization in the presence of a biocompatible zinc-proline initiator through a green route. Irinotecan (Ir) loaded with efficient PLGA core-lipid shell hybrid nanocarriers (lipomers, LPs) were formulated with 1,2-distearoyl--glycero-3-phosphoethanolamine and 1,2-distearoyl--glycero-3-phosphoethanolamine--[amino (polyethylene glycol)-2000] (DSPE-PEG-2000), using soya lecithin, by a nanoprecipitation method, and the fabricated LPs were designated as P-DSPE-Ir and P-DSPE-PEG-Ir, respectively.

Effect of ultrasound-guided ilioinguinal-iliohypogastric nerve block on chronic pain in patients undergoing open inguinal hernia surgery under spinal anesthesia: a randomized double-blind study.

Background: Pre-operative ilioinguinal-iliohypogastric nerve block (II-IHNB) has a proven role in lessening acute postoperative pain and opioid consumption following hernia repair. However, its role in preventing post-herniorrhaphy groin pain (PHGP) is still unknown. The current study aims to assess pre-operative II-IHNB's impact on PHGP three and six months after open inguinal hernia repair under spinal anesthesia.

A Comparative Analysis of the Antimicrobial Efficacy of Nisin in Different Vehicles Against Enterococcus faecalis: An In Vitro Study.

Aim To evaluate and compare the antimicrobial efficacy of nisin in different carriers against . Materials and methods Test materials were divided into four groups of five samples each as follows: group 1 = nisin + 17% ethylenediaminetetraacetic acid (EDTA); group 2 = nisin + 2% chitosan; group 3 = nisin + 2% chlorhexidine; group 4 = nisin + distilled water (control). The antimicrobial effectiveness was assessed using the direct contact method, where a standardized suspension was applied to the test materials.

Unprecedented association: Enormous calculus concomitant with salivary gland tumor.

Calculus represents a mineralized form of bacterial plaque, commonly developing on natural tooth surfaces exposed to a continuous supply of saliva. The salivary composition significantly influences the degree of calculus formation in individuals, exerting a pivotal role in this aspect. Reduced salivary output elevates vulnerability to oral diseases.

ALDH and cancer stem cells: Pathways, challenges, and future directions in targeted therapy.

Human ALDH comprise 19 subfamilies in which ALDH1A1, ALDH1A3, ALDH3A1, ALDH5A1, ALDH7A1, and ALDH18A1 are implicated in CSC. Studies have shown that ALDH can also be involved in drug resistance and standard chemotherapy regimens are ineffective in treating patients at the stage of disease recurrence. Existing chemotherapeutic drugs eliminate the bulk of tumors but are usually not effective against CSC which express ALDH+ population.

Assessment of the Mechanical Properties of Different Suture Materials for Oral Surgery: An In Vitro Tensile Strength Study.

Background: Sutures are essential components of wound closure in oral surgery, and the mechanical properties of suture materials play a crucial role in determining surgical outcomes. Understanding the tensile strengths of various suture materials is vital for selecting the most appropriate material for specific clinical applications.

Objective: This study aimed to assess the tensile strength of suture materials commonly used in oral surgery through an in vitro tensile strength study.

Scaffold overlay of flavonoid-inspired molecules: Discovery of 2,3-diaryl-pyridopyrimidin-4-imine/ones as dual hTopo-II and tubulin targeting anticancer agents.

Almost half of all medicines approved by the U.S. Food and Drug Administration have been found to be developed based on inspiration from natural products (NPs).

Microwave assisted synthesis of ZnInS nanoparticles: effect of power variation for photoresponse and optoelectronic applications.

The ternary ZnInS has recently gained significant attention due to its potential applications in various optoelectronics and photocatalysis sectors. In the current study, ZnInS nanoparticles were prepared using a simple microwave-assisted synthesis method with different irradiation powers varying from 180 W-720 W. Structural analysis confirmed their polycrystalline nature with the appearance of ZnInS and InS phases.

Platelet-Rich Fibrin: A Self-Derived Biomaterial for Surgical Treatment of a Periapical Lesion.

This case report explores the application of platelet-rich fibrin (PRF) as an autologous biomaterial in the surgical management of a periapical cyst in an 18-year-old female patient. The patient presented with pain, discoloration, and swelling in the maxillary left central incisor region, indicative of an asymptomatic periapical lesion associated with a history of trauma. Despite initial endodontic treatment with calcium hydroxide, the lesion persisted, necessitating surgical intervention.

An immunoinformatics approach for design and validation of multi-subunit vaccine against from essential hypothetical proteins.

Unlabelled: Malaria, caused by , remains a pressing global health concern. Advancements in combating this parasite involve the development of a protein vaccine. This study employs immunoinformatics to identify potential vaccine candidates within the repertoire of 218 .