Hepato protective effect of Liv-52 against CCl4 induced lipid peroxidation in liver of rats.

Effect of oral feeding of Liv-52, on lipid peroxidation in normal liver and damaged liver induced by CCl4 of albino rats was studied. While Liv-52 did not show any effect on normal healthy liver cells, it had a significant protective effect against damage by CCl4 as shown by significant decrease in malonaldialdehyde content.

A study of comorbidity in psychoactive substance dependence patients.

The study assessed the lifetime prevalence of comorbidity in forty three DSM III-R opioid and alcohol dependent patients. A total lifetime prevalence rate of 60.5% was found.

A study of platelet aggregation, thromboxane A2 and prostacyclin in central aortic and coronary sinus blood in ischemic heart disease.

Aortic and coronary sinus platelet aggregation, thromboxane A2 (TXA2) and prostacyclin (PG12) levels were studied in fourteen patients of stable angina (SA), six of vasopastic angina (VA) and six control subjects (C). Patients of SA were studied at rest and during incremental atrial pacing and patients with VA were studied at rest and during various stages of vasospasm. Platelet aggregation was studied with different working concentrations of ADP, epinephrine and collagen.

A case of bilateral pulmonary hydatid cysts.

A case of bilateral hydatid lung disease is reported who presented with a history of short duration and large opacities in both lung fields. A trial of medical treatment with albendazole 400 mg BD for 6 weeks failed. The patient was managed by surgical intervention which also ultimately established the diagnosis of hydatid disease.

Regulation of vascular permeability by macrophage-derived chemotactic factor produced in Japanese encephalitis.

The vascular effects of Japanese encephalitis virus (JEV)-stimulated splenic macrophage-derived neutrophil chemotactic factor (MDF) were evaluated in mice. Intraperitoneal injection of MDF in mice resulted in a rapid increase in capillary permeability in a dose-dependent manner as assessed by leakage of intravenously injected radiolabelled albumin ([125I]-albumin) or Evans blue dye. Intradermal inoculation of MDF in rabbits caused [51Cr]-labelled neutrophil emigration and accumulation into injected sites.

Elimination of infection in pulpectomized deciduous teeth: a short-term study using iodoform paste.

This study was conducted to retain the pulp-involved deciduous teeth in dental arches and were restored to function by elimination of infection in pulpectomized deciduous teeth using iodoform paste. Clinically the teeth were evaluated for pain, mobility, and presence or absence of sinus for 3 months. We concluded that the iodoform paste is a suitable root canal filling material for single-visit pulp canal treatment in chronic pulp-infected deciduous teeth.

Platelet serotonin kinetics in acute myocardial infarction before and after thrombolysis.

Platelet count, platelet serotonin uptake and platelet serotonin content were analysed in 21 subjects consisting of 11 patients of evolving acute myocardial infarction (AMI) and 10 matched healthy controls before and after administration of streptokinase. Platelet counts were significantly reduced in AMI with a subsequent rise following thrombolysis. Platelet 5-HT uptake was also significantly increased in AMI and following thrombolysis, it showed a trend towards normalization.

Examination stress in medical student: a study.

The present study was conducted on 40 male and 10 female students appearing for the 1st MBBS examination. Two readings of pulse rate, blood pressure and electro cardiogram were taken viz 6 months (control) and 10 minutes prior to the examination. A significant increase was seen in the pulse rate and blood pressure readings before the examination as compared to the control readings.

Behavior development in normal neonates.

The behavior of normal neonates was studied on day 3, 10 and 30 of life with the help of Brazelton's Neonatal Behavioral Assessment Scale (NBAS). The behavior items were clustered and each cluster was scored. The cluster scores increased on subsequent observations in both term and preterm neonates, the increase usually being significant.

Paroxysmal kinesiogenic choreoathetosis: a frequently misdiagnosed movement disorder.

Paroxysmal kinesiogenic choreoathetosis is rare movement disorder, which is frequently misdiagnosed as an epileptic disorder partly because of a good response to anti-epileptic drugs (Phenytoin sodium). At times these patients are mistaken for a conversion reaction. One such case is described.

A variant of the floor of the carotid canal.

325 skulls were investigated in the present study. The absence of the floor of the carotid canal was found in only one skull, a condition which makes the internal carotid artery vulnerable during a surgical approach to this region.

Biomechanical evaluation of bonding with glass ionomer cement.

This study was designed to determine the bond strength of three commercially available glass ionomer cements when used to bond mesh-backed medium twin standard edgewise (.022" x .028") brackets to enamel surface.

Pathological laughter after right hemispheric infarction.

A lady who had repeated spontaneous pathological laughter after cerebral infarction is described. The role of right hemispheric damage in its causation is discussed.

The practice of ect in India : issues relating yo the administration of ect.

A questionnaire on ECT, tapping altitudes, opinions and usage, was mailed to all medical members of the Indian Psychiatric Society whose addresses were known; 263 (28.8%) responded. This paper, the first in a series that presents the results of the survey, provides demographic data on the respondents and covers issues relating to the administration of ECT.

An immunomodulator in the treatment of schizophrenia : a double-blind study.

In a double blind study, the immunomodulator drug levamisole was administered along with chloropromazine to 18 schizophrenic patients, and efficiency of the combination was compared to that of chloropromazine along with placebo administered to 16 schizophrenic patients. The decrease in T suppressor cell count found in both groups at benchmark was found to be corrected in the patients receiving levamisole and this increase in T suppressor cell count was significantly correlated with the improvement in psychosis. The findings provide evidence in favour of the autoimmune hypothesis of schizophrenia.

Sexual behaviour in a group of urban females.

Sexual behaviour of 75 normal married females was studied. Most of them had a healthy attitude to sex. Frequency of sexual activity decreases with age and duration of marriage.

Role of orthoptic treatment in the management of intermittent exotropia.

30 patients of intermittent ACDS were studied prospectively for a period of 8 weeks to 1 year to evaluate the role of orthoptics in the management of these cases. In patients with convergence insufficiency and a maximum deviation of 25 PD or less the orthoptic treatment was found to be effective in offering symptomatic relief and improving binocular functional status. A reduction in the maximum angle of deviation by 4 PD to 8 PD was observed in 4 patients.

Frequency and severity of depressive symptoms among diabetic patients.

One hundred patients of Diabetes Mellitus (30 insulin dependent and 70 non-insulin dependent) were studied for frequency and severity of depressive symptoms. The subjects were evaluated on Schedule for Standardised Assessment of Affective Disorder (SADD) and Hamilton Rating Scale for Depression (HRSD).Result show that symptoms such as depressed mood-decreased work and activities and loss of weight were present in more than 60% of patients belonging to insulin and non-insulin dependent diabetics.

"A retrospective cohort study for prognostic significance of visual acuity for near over that for distance in anisometropic amblyopia.".

A cohort of 50 anisometropic amblyopes, between the ages of 2.5 to 10 years, was studied retrospectively to assess the prognostic significance of visual acuity for near over that for distance. There is ample evidence in the literature for a significantly lower accommodative response in the anisometropic amblyopic eye.

Isolated olfactory groove neurilemmoma.

A case of neurilemmoma arising from the olfactory groove presenting with headache, vomiting, and visual impairment in a thirty-seven-year-old man is reported. His clinical manifestations are described, with a brief review of three other cases reported in the literature so far.

Acth and the dexamethasone suppression test in depression.

Hypercortisolemia, as measured by baseline serum Cortisol levels (Carroll and Mendels, 1976) and abnormal response to dexamethasone suppression test (DST) (Carroll et at., 1981) is thought to characterize abnormal hypothalamic-pituitory- adrenal (HPA) axis functions in patients of depression. Whether adrenocorticotrophic hormone (ACTH) shows similar abnormalities is a matter of controversy.