Modulation of Proinflammatory Cytokines by Parmotrema reticulatum Derived Dioxepine Derivative and Benzoic Methyl Ester in Adjuvant-Induced Arthritis.

The present investigation aims to study the therapeutic effect and to identify the lead molecules from lichen Parmotrema reticulatum (Pr) that can solve the complications associated with arthritis. Purification of Pr extract led to isolation of two lead molecules i.e.

Characterization of anti bacterial biocomposite films based on poly lactic acid and prosopis juliflora bark powder.

Biocomposites can be a solution for environmental pollution and sustainability by acting as an alternative to petroleum-based products used in the field of packaging and biomedical applications. Herein, an attempt to valorize the potential of Prosopis juliflora plant to fabricate Polylactic acid (PLA) based biocomposites. The biocomposites comprised of Prosopis juliflora bark powder (PJBP) and PLA were fabricated by solution casting method with various weight percentages (Wt%) of PJBP.

Investigating the influence of various metakaolin combinations with different proportions of pond ash and Alccofine 1203 on ternary blended geopolymer concrete at ambient curing.

This paper explores the use of a ternary blended geopolymer concrete (TBGPC) incorporating metakaolin (MK), pond ash (PA), and Alccofine 1203 (AF). Three combinations of MK (25%, 50%, and 75%) with varying proportions of PA and AF were prepared, validating against M grade cement concrete (CC). TBGPC was prepared with an 8 molarity sodium hydroxide, sodium silicate to sodium hydroxide ratio of 2.

Human hand gesture recognition using fast Fourier transform with coot optimization based on deep neural network.

Hand motion detection is particularly important for managing the movement of individuals who have limbs amputated. The existing algorithm is complex, time-consuming and difficult to achieve better accuracy. A DNN is suggested to recognize human hand movements in order to get over these problems.

Heparosan biosynthesis in recombinant Bacillus megaterium: Influence of N-acetylglucosamine supplementation and kinetic modeling.

Heparosan, an unsulfated polysaccharide, plays a pivotal role as a primary precursor in the biosynthesis of heparin-an influential anticoagulant with diverse therapeutic applications. To enhance heparosan production, the utilization of metabolic engineering in nonpathogenic microbial strains is emerging as a secure and promising strategy. In the investigation of heparosan production by recombinant Bacillus megaterium, a kinetic modeling approach was employed to explore the impact of initial substrate concentration and the supplementation of precursor sugars.

Comparative evaluation on surface nanohardness, surface microhardness, surface roughness, and wettability of plant-based organic nanoparticle reinforced polyetheretherketone as an implant material - An in vitro study.

Aim: Synthetic inorganic materials are commonly used as reinforcing agents in polyetheretherketone (PEEK) composite, whereas natural organic plant-based reinforcing agents are negligible. Surface hardness, roughness, and wettability are indicative factors of osseointegration behavior to be used as an implant material. This study evaluated micro surface hardness (MSH), nano surface hardness (NSH), surface roughness (SR), and contact angle (CA) of PEEK-Azadirachta indica reinforced at 10 wt%, 20 wt%, and 30 wt%.

Exploring gene network and protein interaction analysis of neurotrophin signaling pathway in ameloblastoma.

Unlabelled: Ameloblastoma is a non-cancerous but aggressive oral tumor emerging from odontogenic epithelial tissue involved during odontogenesis. Since there is lack in unravelling the complete molecular pathogenesis of ameloblastoma, chemotherapy is less attempted and a lot of disagreement over the optimal treatment option. Hence, till date, wide surgical resection is considered to be the reliable treatment for ameloblastoma.

Extraction and characterization of microcrystalline cellulose from Vachellia nilotica plant leaves: A biomass waste to wealth approach.

Biobased waste utilization is an intriguing area of research and an ecologically conscious approach. Plant-based materials can be used to render cellulose, which is an eco-friendly material that can be used in numerous aspects. In the current investigation, cellulose was extracted from the leaves of the Vachellia nilotica plant via acid hydrolysis.

Characterization and potentiality of plant-derived silver nanoparticles for enhancement of biomass and hydrogen production in Chlorella sp. under nitrogen deprived condition.

Energy is a crucial entity for the development and it has various alternative forms of energy sources. Recently, the synthesis of nanoparticles using benign biocatalyst has attracted increased attention. In this study, silver nanoparticles were synthesized and characterized using Azadirachta indica plant-derived phytochemical as the reducing agent.

Revolutionizing Leishmaniasis Treatment with Cutting Edge Drug Delivery Systems and Nanovaccines: An Updated Review.

Leishmaniasis, one of the most overlooked tropical diseases, is a life-threatening illness caused by the parasite that is prevalent in underdeveloped nations. Over 350 million individuals in more than 90 different nations worldwide are at risk of contracting the disease, which has a current fatality rate of 50 000 mortalities each year. The administration of liposomal Amp B, pentavalent antimonials, and miltefosine are still considered integral components of the chemotherapy regimen.

A Basic Guide to the Propagation and Manipulation of the Clubroot Pathogen, Plasmodiophora brassicae.

Clubroot caused by the obligate parasite Plasmodiophora brassicae is a devastating disease affecting the canola industry worldwide. The socio-economic impact of clubroot can be significant, particularly in regions where Brassica crops are a major agricultural commodity. The disease can cause significant crop losses, leading to reduced yield and income for farmers.

Biofilm Inhibition on Medical Devices and Implants Using Carbon Dots: An Updated Review.

Biofilms are an intricate community of microbes that colonize solid surfaces, communicating via a quorum-sensing mechanism. These microbial aggregates secrete exopolysaccharides facilitating adhesion and conferring resistance to drugs and antimicrobial agents. The escalating global concern over biofilm-related infections on medical devices underscores the severe threat to human health.

The importance of the fourth Greek key motif of human γD-crystallin in maintaining lens transparency-the tale told by the tail.

Purpose: Congenital cataract affects 1-15 per 10,000 newborns worldwide, and 20,000-40,000 children are born every year with developmental bilateral cataracts. Mutations in the crystallin genes are known to cause congenital cataracts. Crystallins, proteins present in the eye lens, are made up of four Greek key motifs separated into two domains.

In vitro and in vivo assessment of antimicrobial, enzymatic, and antifouling properties of self-potent lichen symbiotic bacteria.

This study aimed to comprehensively assess the antimicrobial, antifouling, and antibiofilm-forming potential of lichen symbiotic bacteria against marine fouling bacterial strains. A total of 50 lichen-associated bacteria (LAB) isolates were successfully characterized and evaluated for their effectiveness in mitigating biofouling caused by various marine biofoulers. Through a battery of biological assays encompassing enzymatic, antagonistic, antimicrobial, and antifouling assays, 15 LAB isolates were identified based on their antagonist activities.

Enhanced Method for the Synthesis and Comprehensive Characterization of 1-(4-Phenylquinolin-2-yl)propan-1-one.

We present an enhanced method for synthesizing a novel compound, 1-(4-phenylquinolin-2-yl)propan-1-one (), through the solvent-free Friedländer quinoline synthesis using poly(phosphoric acid) as an assisting agent. The crystal structure of compound is analyzed using FT-IR, and the chemical shifts of its H- and C NMR spectra are measured and calculated using B3LYP/6-311G(d,p), CAM-B3LYP/6-311G(d,p), and M06-2X/6-311G(d,p) basis sets in the gas phase. Additionally, the optimized geometry of quinoline is compared with experimental X-ray diffraction values.

Formulation and validation of probioticated foxtail millet laddu as a source of antioxidant for biological system using response surface methodology.

Probiotics play a critical role in supporting a healthy gut microbiome, which significantly impacts overall health and well-being. While there has been an increase in the availability of probiotic foods in recent years, there may still be limited options and accessibility in certain regions. This study focused on formulating a traditional Indian sweet called laddu enriched with millet and Lactobacillus acidophilus.

Novel smart fiber/metal/chitosan composite as a filter for self-detoxifying photocatalytic wastewater remediation and biomedical applications.

Wastewater treatment remains the most significant delinquent issue world-wide. Generally, wastewater treatment involves filtration followed by acidified de-emulsification through photocatalytic reduction. The aim of the present study is to reduce the use of nanoparticles in wastewater treatment and also to find an appropriate alternative to replace cotton fiber filters used in water treatment plant.

An Experimental Study on Drilling Behavior of Silane-Treated Cotton/Bamboo Woven Hybrid Fiber Reinforced Epoxy Polymer Composites.

Machining is considered to be an important post-manufacturing process. Evaluation of machinability of natural-fiber-reinforced composites is important owing to its wide application spectrum. Current experiments focus on the drilling parameters of cotton/bamboo woven fabric reinforced epoxy composites laminates using a solid twist drill.

Scientific Investigation of Antifouling Activity from Biological Agents and Distribution of Marine Foulers-Coastal Areas of Tamil Nadu.

Biofouling is the result of a biological process that is the accumulation of micro- and macro-organisms on the surfaces of the ship which causes serious environmental problems. The consequence of biofouling includes modifying the hydrodynamic response, affecting heat exchange, can make structures heavier, accelerate or generating corrosion, biodegradation, increasing the fatigue of certain materials, and blocking mechanical functions. It causes severe problems for the objects in the water such as ships and buoys.

Incorporating oregano (Origanum vulgare L.) Essential oil onto whey protein concentrate based edible film towards sustainable active packaging.

Unlabelled: The study's objectives were to develop a packaging film incorporating oregano essential oil, and evaluate the antioxidant, antibacterial, mechanical, and physicochemical activities of the film toward grapes packaging. The films were developed by casting method, after adding nano-emulsion of essential oil into WPC-glycerol film forming solution. The effects of the Oregano Essential Oil (OEO) at different concentrations of 1, 2, 3, and 4% (w/w) in the WPC edible films were studied.

Multifaceted plant growth-promoting traits of indigenous rhizospheric microbes against Phomopsis theae, a causal agent of stem canker in tea plants.

Phomopsis canker is one of the major devastating stem diseases that occur in tea plants caused by the fungal pathogen Phomopsis theae. Rapid development of this disease leads to a capital loss in the tea industry which demands an ecofriendly disease management strategy to control this aggressive pathogen. A total of 245 isolates were recovered from the tea rhizosphere and screened for in vitro plant growth promoting (PGP) traits and antagonism against P.