Healthy lifestyle before and during pregnancy to prevent childhood obesity: study protocol for a parallel group randomised trial - the PRE-STORK trial.

Introduction: The global prevalence of people living with overweight has tripled since 1975 and more than 40% of Danish women enter pregnancy being overweight. With the increasing rates of obesity observed in children, adolescents and adults, there is an urgent need for preventive measures. Risk factors for childhood obesity include maternal overweight or obesity before conception and excessive weight gain during pregnancy.

Temporal order of atrial fibrillation and acute myocardial infarction and associated prognosis in the Danish Diet, Cancer and Health cohort.

Background: Atrial fibrillation (AF) and acute myocardial infarction (AMI) share risk factors and are bidirectionally associated. Several studies found higher risks of outcomes in individuals with both conditions. Whether the risks of outcomes differ according to temporal order of AF and AMI is unclear.

Mechanical circulatory support for patients with infarct-related cardiogenic shock: a state-of-the-art review.

Acute myocardial infarction-related cardiogenic shock (AMI-CS) is a severe, life-threatening condition characterised by inadequate tissue perfusion due to the heart's inability to pump blood effectively. The pathophysiology of AMI-CS usually arises from the sudden loss of myocardial contractility, leading to a decrease in cardiac output and systemic hypoperfusion. In approximately 90% of AMI-CS cases, the left ventricle is the primary site of dysfunction.

Trends in childhood asthma in Denmark, Finland, Norway and Sweden.

Aim: Estimate the incidence of asthma among children aged 0 to 15 years in Denmark, Finland, Norway and Sweden during 2000-2017.

Methods: Cases of preschool asthma (up to 6 years) and school-age asthma (from 6 years) were identified through national registers using an algorithm including hospital diagnoses and prescription medicines. The respective cumulative incidence (CI) was estimated in 1-year age intervals for each country and birth year.

Rocking Motion Therapy for Delirious Patients in the ICU: A Multicenter Randomized Clinical Trial.

Objectives: Rocking motion therapy has been shown to calm people with dementia but has never been investigated in delirious patients in the ICU. The aim of this clinical trial was to investigate the efficacy and safety of a rocking motion vs. nonrocking motion chair on the duration of delirium and intensity of agitation in ICU patients with delirium.

Rocking Motion Therapy for Delirious Patients in the ICU: A Multicenter Randomized Clinical Trial.

Objectives: Rocking motion therapy has been shown to calm people with dementia but has never been investigated in delirious patients in the ICU. The aim of this clinical trial was to investigate the efficacy and safety of a rocking motion vs. nonrocking motion chair on the duration of delirium and intensity of agitation in ICU patients with delirium.

Patient and wound factors associated with WOUND-Q scales measuring health-related quality of life: An international cross-sectional study.

The WOUND-Q is a patient-reported outcome measure for individuals with any type of chronic wound. This study aimed to identify patient and wound factors associated with the four WOUND-Q health-related quality of life (HRQL) scales: Life impact, Psychological, Sleep, and Social. Adults with a chronic wound were recruited internationally through clinical settings between August 2018 and May 2020, and through an online platform (i.

[Hypoglossus paresis after tonsillectomy].

This is a case report of a rare hypoglossal nerve paresis after tonsillectomy in a healthy 29-year-old woman. While she made a full recovery, she experienced 6-8 weeks of dysphagia, dysarthria and had to be readmitted because of dehydration. As direct intraoperative trauma is unlikely due to the protected course of the nerve, we discuss possible mechanisms and suggest precautions to avoid similar neuropraxia - such as avoiding overinflation of the laryngeal mask airway, regularly relieving the tongue pressure and using careful manipulation of the tongue base if necessary.

Assessment of a colposcopic scoring system (Swedescore) to reduce the number of cervical biopsies: a protocol for a clinical multicentre non-randomised intervention study in Denmark.

Introduction: Colposcopy is a standard procedure for evaluating cervical abnormalities and collecting cervical biopsies. The procedure is associated with intra- and inter-observer variation. A colposcopic scoring system, Swedescore, has been designed to standardise and facilitate colposcopy training.

Cognitive impairment in patients with melanoma before adjuvant immune checkpoint inhibitor therapy and associations with brain gray matter, catechol-O-methyltransferase genotype, and psychological factors.

Background: Cancer-related cognitive impairment (CRCI) is a significant concern in patients with cancer but understanding its prevalence and risk factors in patients with malignant melanoma (MMPs) remains limited. This study explores CRCI via a multifaceted approach integrating neurobiological, genetic, and psychological assessments.

Methods: Cognitive functioning across multiple domains was assessed via neuropsychological tests in 47 MMPs before adjuvant immune checkpoint inhibitor therapy, compared with 53 matched healthy controls (HCs).

[Christmas article: Maximum bladder capacity at an anesthesiology department’s Christmas party].

Introduction: Christmas parties, a longstanding Danish tradition, became festive occasions in the 1960s. This study examines if healthcare professionals, especially doctors and nurses, have larger bladder capacities than the general population, as they often delay restroom breaks.

Methods: At the North Zealand University Hospital Department of Anesthesiology's 2023 Christmas party, participants delayed urination until a strong urge occurred.

[Christmas article: From diagnosis to delicacy: using MR and DXA scanners to roast Christmas duck].

Introduction: The holiday season poses a unique challenge for hospital staff, especially on night shifts, who must juggle their duties with preparing a festive Christmas meal. This study investigates the novel idea of using hospital MRI scanners to cook duck breasts during shifts. MRI scanners, which use magnetic fields and radiofrequency (RF) pulses for imaging, also generate heat, potentially suitable for cooking.

[Christmas article: A little booze to warm you up - true or false? A thermographic Christmas study].

Introduction: In December, it is common to enjoy mulled wine, often believed to warm the body. While alcohol can cause peripheral vasodilation, it remains unclear whether it truly increases body warmth or is merely a subjective sensation. This study aimed to evaluate the warming effect of mulled wine using thermography.

[Melanoma in pregnancy].

The melanoma incidence is rising. Among pregnant women, melanoma is one of the most common cancers accounting for approximately 30% of all cancers. Timely diagnosis is critical, but management of pregnant women with melanoma lacks international consensus, and uncertainties may arise.

[Spontaneous coronary artery dissection].

Spontaneous coronary artery dissection (SCAD) presents a life-threatening condition, prevalent among young women, comprising up to 35% of acute coronary syndrome cases. It involves sudden, trauma-free splitting of coronary artery walls, reducing blood flow and mimicking symptoms of acute myocardial infarction. Despite recent attention, treatment remains debated.

Clinical characteristics and diagnostic accuracy of preliminary diagnoses in adults with infections in Danish emergency departments: a multicentre combined cross-sectional and diagnostic study.

Objective: Rapid and accurate infection diagnosis is a prerequisite for appropriate antibiotic prescriptions in an ED. Accurately diagnosing acute infections can be difficult due to nonspecific symptoms and limitations of diagnostic testing. The accuracy of preliminary diagnoses, established on the initial clinical assessment, depends on a physician's skills and knowledge.

Occipital nerve stimulation: A detailed description of a surgical approach and a discussion on implantation techniques.

Objective: Occipital Nerve Stimulation (ONS) is increasingly used to treat a range of chronic, refractory headache conditions, most notably chronic cluster headache (CCH). Despite this, there is still no consensus on the optimal implantation technique. Clinical reports and reviews in the field have reported remarkably high complication rates of which several can be directly related to the surgical approach.

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Psoriasis is a common chronic inflammatory skin disease with several clinical subtypes. Recent discoveries in the genetics and immunology of the disease, particularly in plaque psoriasis, have revolutionised the treatment of patients with psoriasis. An understanding of the differences in genetics and immunology between different psoriasis subtypes is emerging.

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This review underscores that psoriasis can manifest in infancy, negatively impacting the quality of life of children and their families. It often presents as minor, less pruritic plaques with subtle characteristics. Pediatric psoriasis is associated with an increased risk of arthritis, metabolic disorders, and psychological conditions, necessitating regular screenings.

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Patiens with psoriasis and mild to moderate skin disease can be treated with topical agents. This review finds that the most effective topical treatment is calcipotriol and betamethasone combination formulations. Pure topical corticosteroids continue to have a role in the treatment of psoriasis, as they are available in many strengths and formulations that facilitate ease of use.