1,556 results match your criteria: "Jr Hospital[Affiliation]"
Trends and outcomes of different mechanical circulatory support modalities for acute myocardial infarction associated cardiogenic shock in patients undergoing early revascularization.
Am Heart J Plus
October 2024
Department of Cardiology, Louisiana State University, Shreveport, LA, USA.
Article Synopsis
- The study investigates the outcomes of different Mechanical Circulatory Support (MCS) devices, specifically comparing ECMO and Impella, in patients with cardiogenic shock due to acute myocardial infarction (AMI-CS).
- Data from the national readmission database revealed that the majority of patients received Impella, while the ECMO group was generally younger with fewer health issues.
- Despite advances in MCS technologies, there was no significant change in mortality rates for AMI-CS between 2016 and 2020, and ECMO had higher adverse outcomes compared to Impella, indicating a need for further research.
Perspectives of healthcare workers on the acceptability of donor human milk banking in Southwest Nigeria.
Int Breastfeed J
October 2024
Department of Radiology and Imaging Services, John H Stroger Jr Hospital of Cook County, Chicago, IL, 60612, USA.
Article Synopsis
- The World Health Organization emphasizes the importance of Mother's Own Milk (MOM) and donor human milk (DHM) for breastfeeding support, especially in developing countries like Nigeria, where DHM is often scarce.
- A study in Ekiti State found that out of 321 healthcare workers surveyed, while many had good knowledge of DHM, there were varying attitudes towards its safety and efficacy, with some reluctance to accept DHM for their own children.
- Overall, the study showed that most healthcare workers would encourage mothers to donate milk and use DHM for infants in their care, but negative perceptions and influences from the media impacted their openness to DHM.
Sex disparities in outcomes of transcatheter aortic valve implantation- a multi-year propensity-matched nationwide study.
Int J Cardiol
January 2025
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Division of Cardiology, Department of Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, USA.
Article Synopsis
- This study looked at how men and women do after a heart procedure called TAVI, which helps with a problem called aortic stenosis.
- It found that women faced more serious complications right after the procedure, like higher chances of dying and having strokes, compared to men.
- However, men had a higher chance of needing to go back to the hospital within 30 and 90 days after the procedure, but both men and women got better faster from 2016 to 2020.
Postoperative outcomes after receipt of ertapenem antimicrobial prophylaxis for colon surgery: a multicenter retrospective cohort study.
Infect Control Hosp Epidemiol
October 2024
Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University, Durham, NC, USA.
Objective: To evaluate postoperative outcomes among patients undergoing colon surgery who receive perioperative prophylaxis with ertapenem compared to other antibiotic regimens.
Design And Setting: Multicenter retrospective cohort study among adults undergoing colon surgery in seven hospitals across three health systems from 1/1/2010 to 9/1/2015.
Methods: Generalized linear mixed logistic regression models were applied to assess differential odds of select outcomes among patients who received perioperative prophylaxis with ertapenem compared to other regimens.
Toripalimab combined with definitive chemoradiotherapy for locally advanced cervical squamous cell carcinoma patients (TRACE): A single-arm, phase I/II trial.
Cancer Immunol Immunother
October 2024
Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Ruijin Second Road, Shanghai, 200025, China.
Article Synopsis
- A phase I/II trial evaluated the safety and effectiveness of toripalimab alongside chemoradiotherapy for patients with locally advanced cervical squamous cell carcinoma.
- Twenty-two patients participated, receiving a combination of toripalimab and concurrent chemoradiotherapy, with a focus on safety and progression-free survival over two years.
- Results indicated a high objective response rate of 100%, with two-year progression-free survival at 81.8% and overall survival at 90.9%, demonstrating promising outcomes for this treatment combination.
Factors Predicting Spontaneous Closure of Patent Ductus Arteriosus in Very Low Birth Weight Neonates.
Cureus
August 2024
Neonatology, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Background Patent ductus arteriosus (PDA) is a relatively rare condition among neonates in the United States, estimated at approximately 1 in every 2,000 births. Managing hemodynamically significant patent ductus arteriosus (hsPDA) in very low birth weight (VLBW) neonates remains a challenge. This study aims to explore and report on the spontaneous closure of hsPDA in VLBW infants in a clinical setting.
View Article and Find Full Text PDFSubstance use and menopausal symptoms among people with and without HIV in the US, 2008-2020.
Menopause
October 2024
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.
Article Synopsis
- The study investigates how substance use impacts menopausal symptoms in people living with and without HIV in the US over a 12-year period.
- Data from the Women’s Interagency HIV Study involved self-reported information on menopausal symptoms, substance use, and demographic data analyzed using logistic regression.
- Findings reveal that current heavy alcohol, cumulative tobacco, and marijuana use are linked to increased frequency of vasomotor symptoms, while heavy alcohol and opioid use are associated with mood symptoms, highlighting the need for targeted interventions during menopause.
Gender disparities in outcomes of cardiogenic shock secondary to Takotsubo cardiomyopathy.
Am Heart J Plus
October 2024
Department of Cardiology, Louisiana State University, Shreveport, LA, USA.
Article Synopsis
- Takotsubo cardiomyopathy (TTC) primarily affects postmenopausal females, but recent data show that men have worse outcomes, especially with cardiogenic shock (TTC-CS).
- In a study analyzing hospitalizations for TTC-CS, 74.1% of cases were female, yet male patients had higher mortality rates and complications such as cardiac arrest and acute kidney injury.
- Despite males experiencing higher hospitalization costs and longer stays, there were no significant differences in readmission rates over 30, 90, and 180 days, suggesting stable mortality with declining use of certain treatments.
Article Synopsis
- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
- In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
- There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
Strategies for overcoming obstacles to hands-on cosmetic and laser training in dermatology residency.
J Am Acad Dermatol
January 2025
Department of Dermatology, Northwestern Feinberg School of Medicine, Chicago, Illinois; Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, Illinois; Department of Otolaryngology, Northwestern Feinberg School of Medicine, Chicago, Illinois; Department of Medical Social Sciences, Northwestern Feinberg School of Medicine, Chicago, Illinois. Electronic address:
Efficacy of thoracic endovascular aortic repair versus medical therapy for treatment of type B aortic dissection.
BMC Surg
September 2024
Department of Clinical Medicine, Weill Cornell Medical College, Ar-Rayyan, Qatar.
Background: Techniques in endovascular therapy have evolved to offer a promising alternative to medical therapy alone for Type B aortic dissections (TBADs).
Aim: The aim of this meta-analysis was to compare mortality and overall complications between thoracic endovascular aortic repair (TEVAR) and best medical therapy (BMT) in patients with TBADs.
Methods: We included randomized control trials and prospective or retrospective cohort studies that compared TEVAR and BMT for the treatment of type B aortic dissection.
Adult Hepatoblastoma and Concomitant Hepatitis B Infection.
ACG Case Rep J
September 2024
Department of Gastroenterology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL.
We report a case of hepatoblastoma in a 26-year-old man with a background of type 2 diabetes mellitus and untreated hepatitis B, initially presenting with hematemesis and a recent diagnosis of hepatocellular carcinoma on computed tomography scan from a different hospital and recent referral to hospice. On presentation to our hospital, given atypical presentation for hepatocellular carcinoma, histological examination was made, revealing hepatoblastoma. Treatment included chemotherapy and management of hepatitis B, although complicated by chemotherapy-induced cytopenias and tumor progression, ultimately losing the patient to follow-up after 2 years.
View Article and Find Full Text PDFVascular Consequences: A Case Report on Posterior Circulation Infarction as a Sequela of COVID-19.
Cureus
July 2024
Radiodiagnosis, New Desinganad Scans, Kayamkulam, IND.
This case report presents a posterior circulation infarction in a previously healthy 39-year-old male, three months post-severe COVID-19. He presented with right-sided homonymous hemianopia and elevated inflammatory markers and D-dimer levels. Imaging revealed an acute left occipital infarct.
View Article and Find Full Text PDFClonal heterogeneity in STAG2m myeloid neoplasms: the Mayo Clinic experience.
Ann Hematol
October 2024
Division of Hematology, Mayo Clinic, Rochester, MN, 55905, USA.
Fungal Infections in Hospitalized Patients of Systemic Lupus Erythematosus: A United States Nationwide Cohort Analysis.
Cureus
July 2024
Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Article Synopsis
- This study analyzes the risk of fungal infections in patients with systemic lupus erythematosus (SLE) who are on immunosuppressive therapy, highlighting increased susceptibility among certain demographics, particularly Hispanic and Asian individuals, and those using steroids or with coexisting conditions like HIV or certain cancers.
- Researchers examined hospitalization data from the National Inpatient Sample (NIS) for patients diagnosed with both SLE and specific fungal infections from 2016 to 2020 to identify trends and risk factors.
- Findings revealed that female SLE patients had lower odds of fungal infections, while there were significant geographical variations in infection rates across the U.S., with a noted decline in hospitalization rates for non-SLE fungal infections during the study
Article Synopsis
- Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is often linked to rheumatoid arthritis (RA), leading to more intense inflammation and a reduced quality of life for affected patients.
- A study using National Inpatient Sample data from 2016 to 2020 analyzed hospitalized IBD patients to compare outcomes for those with and without RA, focusing on mortality, hospital length of stay, and total charges.
- The results showed that IBD patients with RA were older, had a higher proportion of females, and faced greater cardiovascular risks, indicating a need for improved management strategies for these coexisting conditions.
Evaluating the association between time to skin grafting for truncal burn patients and complications: a comparative cohort study using the National Trauma Data Bank.
Int J Surg
August 2024
Department of Trauma and Burn Surgery, John H. Stroger, Jr. Hospital of Cook County, Chicago.
Article Synopsis
- * Results showed that patients with complications, like infections or graft failure, waited significantly longer for grafting (about 413 hours vs. 265 hours), and those with diabetes had higher complication rates.
- * While delays in skin grafting led to longer hospital stays and increased complications, they did not affect overall mortality, suggesting other factors might contribute to patient outcomes.
Transcatheter Aortic Valve Replacement Across Hemodynamic Subtypes of Severe Aortic Valve Stenosis: A Network Meta-analysis.
J Soc Cardiovasc Angiogr Interv
March 2024
Department of Cardiology, Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania.
Background: Studies assessing outcomes of transcatheter aortic valve replacement (TAVR) in patients with severe aortic valve stenosis (AS) with hemodynamic subtypes have demonstrated mixed results with respect to outcomes and periprocedural complications. This study aimed to assess the outcomes of TAVR in patients across various hemodynamic subtypes of severe AS.
Methods: PubMed, Embase, and Cochrane databases were searched through September 2023 to identify all observational studies comparing outcomes of TAVR in patients with paradoxical low flow low gradient (pLFLG), classic LFLG, and high gradient AS (HGAS).
A Report of a Rare Case of Kounis Syndrome in a Patient With HIV/AIDS and Mpox.
Cureus
July 2024
Cardiology, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Article Synopsis
- * A case study highlights a 45-year-old man with HIV/AIDS who experienced chest pain and low blood pressure during a vancomycin infusion, which resulted in a ST-elevation myocardial infarction (STEMI).
- * After ceasing the vancomycin, the patient's ECG changes and symptoms resolved, with heart catheterization revealing normal coronary arteries.
Trends and outcomes of inpatient cardiac implantable electronic device transvenous lead extractions: a nationwide analysis.
J Interv Card Electrophysiol
August 2024
Section of Electrophysiology, Division of Cardiology, Department of Medicine, Rush University Medical Center, 1717 W Congress Pkwy/suite 317 Kellogg, Chicago, IL, 60612, USA.
Article Synopsis
- Higher rates of cardiac implantable electronic device (CIED) implantations are linked to increased lead failures and the need for transvenous lead extractions (TLE), prompting this study to evaluate TLE admissions and safety outcomes from 2016 to 2019.* -
- The study analyzed 30,128 TLE hospitalizations, finding a 3.21% in-hospital mortality rate, with factors like age and existing health conditions raising mortality; those with a history of sternotomy fared better than those without.* -
- Despite a low overall mortality rate, female patients experienced more cardiac tamponade but had shorter hospital stays and lower costs, with no significant gender difference in mortality rates.*
Transcatheter Versus Surgical Aortic Valve Replacement in Recipients of Solid Organ Transplants and Liver Cirrhosis: A Propensity-Matched Analysis of National Readmission Data.
Am J Cardiol
October 2024
Department of Cardiology, Louisiana State University, Shreveport, Louisiana.
Article Synopsis
- Transcatheter aortic valve replacement (TAVR) is becoming more common in the U.S., especially among patients with severe aortic stenosis, but there is limited research on its effectiveness for solid organ transplant (SOT) recipients and patients with liver cirrhosis.
- A study using data from 2016 to 2020 compared outcomes between TAVR and surgical aortic valve replacement (SAVR) in these populations and found that TAVR is linked to significantly lower rates of in-hospital mortality and other adverse events compared to SAVR.
- Both groups showed similar readmission rates after six months, but TAVR resulted in shorter hospital stays and lower costs compared to SAVR, highlighting
Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease.
World J Cardiol
July 2024
Division of Cardiology, Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL 60612, United States.
Article Synopsis
- - The study examines the impact of chronic kidney disease (CKD) on readmission rates for patients undergoing transcatheter aortic valve replacement (TAVR) due to severe aortic stenosis, highlighting the challenge it presents in terms of patient outcomes.
- - An analysis of a national database revealed that 32.4% of CKD patients who had TAVR were readmitted within 90 days, with predictors including female gender, longer hospital stays, and additional health conditions like diabetes and heart failure.
- - The primary reasons for readmission were identified as congestive heart failure, sepsis, and complete atrioventricular block, emphasizing the need for better monitoring and follow-up care to reduce readmission rates.
Impact of frailty in hospitalized patients undergoing catheter ablation for atrial fibrillation.
J Cardiovasc Electrophysiol
October 2024
Department of Cardiology, Louisiana State University, Shreveport, Louisiana, USA.
Background: Catheter Ablation (CA) is an effective treatment for atrial fibrillation (AF). However, frail elderly patients have been understudied due to their exclusion from landmark trials.
Objectives: Our study aims to evaluate outcomes in this population.
Article Synopsis
- The NRG/RTOG 0436 study investigated whether adding cetuximab to chemoradiation for non-operative esophageal cancer would improve patient-reported outcomes (PROs), focusing on the FACT-Esophageal cancer subscale (ECS).
- The study was stopped early due to failing to meet overall survival (OS) targets; among 344 enrolled patients, those receiving CRT plus cetuximab showed less improvement in ECS compared to those receiving standard CRT alone (37% vs. 53%).
- Overall, the results indicated that adding cetuximab did not enhance PROs related to symptoms, swallowing, or eating, and there was no significant link between clinical complete
Esophageal cancer mortality disparities between Black and White adults in the United States, 1999-2020: insights from CDC-WONDER.
J Gastroenterol Hepatol
November 2024
Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
Article Synopsis
- - This study examines esophageal cancer mortality trends from 1999 to 2020 among Black and White adults in the U.S., highlighting significant racial disparities in death rates.
- - Over the years, Black adults saw a notable decline in esophageal cancer mortality rates, while rates for White adults stabilized, leading to a narrowing of the racial gap.
- - The findings indicate the need for targeted public health strategies to improve healthcare access and manage risk factors, especially given the unique trends observed between different racial groups and genders.