4 results match your criteria: "Joshi Clinic and Lilavati Hospital and Research Centre[Affiliation]"

Monkeypox was a zoonotic infection, first detected in parts of northern Africa in the 1970s. Monkeypoxvirus, the causative agent of monkeypox, is a species of genus Orthopoxvirus and is closely related to long-eradicated smallpox caused by variola virus. Outbreaks in the West (in USA, UK, and Ireland) along with periodic re-emergence of the disease in parts of Africa have generated concern among global health bodies due to the existent deficiency of guidelines for management of the disease.

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Article Synopsis
  • Favipiravir is an oral antiviral medication approved in India for treating mild-to-moderate COVID-19, and this study aimed to evaluate its effectiveness and safety in real-world settings.
  • The study involved examining medical records of 360 patients across four centers, finding a high clinical cure rate of over 90% with average recovery times of about four to five days.
  • The results indicated that while 8% of patients experienced some adverse effects like liver enzyme elevation and fatigue, these were generally mild and temporary, suggesting favipiravir is a well-tolerated treatment option.
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The Asian-Indian phenotype of type 2 diabetes mellitus is uniquely characterized for cardio-metabolic risk. In the context of implementing patient-centric holistic cardio-metabolic risk management as a priority, the choice of various combinations of antidiabetic agents should be individualized. Combined therapy with two classes of antidiabetic agents, namely, dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors, target several pathophysiological pathways.

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Tight glycemic control has been recognised as the cornerstone of modern diabetes management. Until recently, glycated hemoglobin (HbA1c) was the only reliable tool for measuring glycemic control, but it is not an ideal metric as it is retrospective, unable to pick up hypo- and hyperglycemic excursions and prone to interference by conditions such as anemia and hemoglobinopathies. The advent of continuous glucose monitoring systems is a giant leap in diabetes management as it enables visualisation of glucose trends over periods of time, helping in identification of hypo- and hypoglycemic events and enabling appropriate treatment decisions to be made.

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