1,149 results match your criteria: "Jordan University Hospital[Affiliation]"

Background: Electronic patient-reported outcomes (ePROs) have been shown to enhance healthcare quality by improving patient symptom management or quality of life (QoL). However, ePROs data for urothelial cancer (UC) patients receiving systemic therapies are scarce, and the application of ePROs in this patient cohort may need specific setups. This study tested the feasibility of ePROs for UC patients receiving systemic therapies in the outpatient clinic of a tertiary care center.

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Rhinoplasty, or nose job surgery (NJS), alters the nose's size, shape, or structure. It can fix congenital abnormalities, enhance breathing, or improve nose attractiveness. Due to Jordan's high financial standing, cultural influences, and trained surgeons, rhinoplasty is the most prevalent cosmetic surgery in the USA and Jordan.

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Familial Mediterranean Fever (FMF) is an inherited autosomal recessive disorder resulting from the inheritance of MEFV gene mutations. Patients with FMF are at increased risk of secondary amyloidosis, namely type AA. In some Mediterranean populations, the α genotype was associated with the development of renal amyloidosis, a finding not reproduced in other populations.

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Article Synopsis
  • - Lymphedema is a condition with primary and secondary forms that leads to limb swelling and complications; management involves a collaborative approach, including physical therapy and surgery, aiming to enhance patients' quality of life.
  • - A case study of a 40-year-old male with severe congenital lymphedema shows that repeated debulking surgeries improved his limb function and appearance, despite previous unsuccessful treatments.
  • - Advanced lymphedema may require complex surgical procedures, like the Charles procedure, which involves removing tissue layers and using them for grafting; these tailored strategies are essential to successful outcomes and highlight the need for personalized patient care.
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Cigarette smoking negatively impacts mesenchymal stem cell functionality, including proliferation, viability, and differentiation potential. Adipose-derived mesenchymal stem cells (ADMSCs) are increasingly used for therapeutic purposes, but the specific effects of smoking in vivo on these cells are poorly understood. This study investigates the effects of cigarette smoke on the proliferation, viability, gene expression, and cellular functions of ADMSCs from smoking and non-smoking donors.

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Interest has arisen in exploring the off-label application of left-sided percutaneous mechanical aspiration, where conventional management strategies may not suffice. Percutaneous mechanical aspiration has been shown to be effective as a diagnostic and therapeutic intervention in select patients with infective endocarditis. This paper hereby reports the first case of a successful transeptal large bore manual aspiration device (AlphaVac; Angiodynamics) for nonbacterial thrombotic endocarditis with total resolution of associated severe mitral valve regurgitation.

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Background: The integration of Artificial Intelligence (AI) tools like ChatGPT into medical education is expanding, offering benefits such as efficient information synthesis. However, concerns about the accuracy, reliability, and proper use of these tools persist. Understanding medical students' perceptions of ChatGPT is crucial for optimising its use in educational settings.

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: This study aims to investigate the role of congenital single nucleotide thrombophilia in young females with early recurrent pregnancy loss (RPL). : We studied 120 pregnant females with RPL and 80 matched females as a control with no RPL. Females were aged ≤ 35 years, had at least two consecutive first-trimester RPLs, and the acquired cause of RPL was excluded.

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Leydig cell tumors (LCT) are rare neoplasms that represent less than 0.1% of all ovarian tumors. This tumor usually presents with signs and symptoms of excess androgen levels.

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Background: Lymphocyte-based inflammatory indices such as monocyte-to-lymphocyte ratio (MLR) have long been recognized as reliable coronary artery disease (CAD) predictors. More recently, novel indices like the Systemic Inflammatory Index (SII), Systemic Inflammatory Response Index (SIRI), and Systemic Immune-Inflammation Index (SIIRI) have emerged. These newer markers offer a more comprehensive assessment of inflammation by integrating multiple immune cell types, potentially enhancing the prediction of cardiovascular outcomes.

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Article Synopsis
  • - The study evaluated the presence of Methicillin-Resistant Staphylococcus (MRS) on the skin and in the nasal cavities of healthcare workers (HCWs), finding a significant number were carriers of these resistant bacteria, particularly MRSA among male HCWs and MRSE among nurses.
  • - Swab samples collected from HCWs were cultured to identify MRS and assess their susceptibility to antibiotics, showing a high incidence of methicillin resistance particularly in doctors and nurses.
  • - The findings indicated the need for improved preventive measures against the spread of these infections in hospitals, with vancomycin suggested as a highly effective treatment for MRSA and MRSE infections.
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Background: Several screening models have recently been applied to study awareness and help people make informed decisions regarding cancer screening.

Aims: This study aimed to explore the knowledge, attitudes, and lung cancer screening health beliefs (LCSHBs) among Jordanians. Moreover, we intended to translate the LCSHBs scale into the Arabic language and test its validity and reliability.

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Purpose: Olfaction plays a vital role in regulating nutrition, avoiding potentially dangerous situations, and modulating behavior along with interpersonal relationships. Many common disorders can have a negative impact on olfaction; one of these is obesity. Bariatric surgery induces weight loss, and current evidence suggests that it can cause improvement in olfaction.

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Purpose: The most prevalent chronic liver disease in both developed and developing nations is Metabolic dysfunction-associated Steatotic Liver Disease (MASLD). The condition increases the risk of comorbidities and liver-related morbidity and mortality. The public's awareness and medical personnel's understanding are essential in creating countermeasures to stop the disease's spread; a positive attitude is essential for early screening.

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Interrater agreement and reliability of the Bosniak classification for cystic renal masses version 2019.

Urol Oncol

October 2024

Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman, Jordan; Department of Urology, Medical University of Vienna, Vienna, Austria; Department of Urology, Weill Cornell Medical College, New York, NY.

Background: The Bosniak classification for cystic renal masses has undergone refinements since its inception. The 2019 version provides more objective criteria to enhance interrater agreement but needs validation. This study compares the interrater agreement of the 2005 and 2019 Bosniak classifications for cystic renal masses.

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Establishment of a human induced pluripotent stem cell (iPSC) line (JUCTCi018-A) from a patient with Charcot-Marie-Tooth disease type 2EE (CMT2EE) due to a homozygous c.122G > A p.(Arg41Gln) mutation in the MPV17 gene.

Stem Cell Res

December 2024

Cell Therapy Center, the University of Jordan, Amman, Jordan; Hemostasis and Thrombosis Laboratory, School of Medicine, the University of Jordan, Amman, Jordan; Department of Hematology and Oncology, Jordan University Hospital, Amman, Jordan. Electronic address:

Article Synopsis
  • Charcot-Marie-Tooth disease (CMT) is a genetic condition that impacts the peripheral nervous system.
  • A new induced pluripotent stem cell (iPSC) line, JUCTCi018-A, was developed from skin cells of a CMT2EE patient carrying a specific mutation in the MPV17 gene.
  • This iPSC line exhibits normal characteristics and pluripotency, making it a useful tool for studying the mechanisms of CMT2EE.*
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This study aimed to investigate the effect of acidic media storage (gastric acid and Coca-Cola) on the mechanical properties of CAD/CAM materials. Three types of materials were tested: a polymer-infiltrated ceramic network (PICN) (Vita Enamic (En), VITA Zahnfabrik, Germany), a resin composite block (RCB) (Cerasmart (Cs), GC Corp, Japan), and a conventional resin-based composite (Gradia direct (Gr), GC Corp, Japan), which was used as a control. Beam-shaped specimens of each material, with dimensions of 16 mm × 4 mm × 1.

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  • SWI/SNF complexes are multi-subunit chromatin remodelers linked to disruptions in over 20% of human tumors, with specific attention given to the SMARCD family in prostate cancer.
  • A study using immunohistochemistry on tissue samples found that SMARCD1 and SMARCD3 protein levels were significantly higher in tumor tissues compared to benign tissues, particularly in lymph node metastases.
  • While SMARCD1 did not correlate with clinical outcomes, low SMARCD3 levels were associated with increased progression to metastasis, suggesting potential roles as biomarkers in prostate tumorigenesis.
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  • The study investigates the relationship between maternal diabetes and cryptorchidism (undescended testes) in Jordanian male children, as this connection has not been thoroughly explored before.
  • Over a 10-year period, data was collected from 368 children with cryptorchidism, of which 29 had mothers with gestational or type II diabetes, revealing that about 25% also had other related anomalies, predominantly genital ones.
  • The findings indicate that while there are no significant differences in treatment timelines between children of diabetic and non-diabetic mothers, diabetic mothers are more likely to have children with additional urogenital anomalies, underscoring the need for further research and better screening practices for gestational diabetes.
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Background Patients' long length of stay (LOS) in the emergency department (ED) is a common measure of quality of care that could be a cause of increased morbidity and mortality. This quality improvement project (QIP) aimed to identify causes of long LOS and to improve common causes such as long consultation times. Methodology Over two months, three plan, do, study, and act (PDSA) cycles were conducted aiming to identify causes of long ED LOS and improve common causes that extended ED LOS beyond four hours.

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Article Synopsis
  • Mesenchymal stem cells (MSCs) often face high mortality rates after transplantation, making hypoxia pre-conditioning a vital technique to enhance their survival and functionality.
  • Induced pluripotent stem cell-derived MSCs (iMSCs) are emerging as a promising alternative, and this study investigated how short-term severe hypoxia (1% O for 24 hours) affects their growth, viability, and differentiation.
  • The results showed that while hypoxia negatively impacted iMSCs' proliferation and viability, it might have long-term benefits for their growth and differentiation, indicating a need for further research on the effects of prolonged hypoxia recovery.
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