Exploring the Anticancer Effect of on Colorectal Cancer: Insights From Eight Colorectal Cancer Cell Lines.

Colorectal cancer (CRC) is a prevalent and deadly disease, necessitating the exploration of novel therapeutic strategies. Traditional chemotherapy often encounters drug resistance and adverse side effects, highlighting the need for alternative approaches. , a plant rich in phytochemical constituents, was investigated for its potential as an anticancer agent against colorectal cancer (CRC).

Novel Transfer Learning Approach for Detecting Infected and Healthy Maize Crop Using Leaf Images.

Maize is a staple crop worldwide, essential for food security, livestock feed, and industrial uses. Its health directly impacts agricultural productivity and economic stability. Effective detection of maize crop health is crucial for preventing disease spread and ensuring high yields.

Gastroesophageal reflux disease in medical students: a cross-sectional study.

Introduction: Common clinical problems are frequently seen in medical students. Gastroesophageal reflux disease (GERD) is increasingly seen in clinics and is taken seriously into consideration; from this point, we start discussing this disorder. The most important part is to find out the prevalence of GERD among medical students and determine the most dominant risk factors that affect the prognosis of the disease.

gastritis in Jordanian children: persistence versus resolution.

Introduction: () is the most common cause of infectious gastritis. is an infection that is typically acquired during childhood.

Aim: This study aims to describe children with infection and compare the clinicopathological features of children with resolved and persistent infection.

Data on full stationary wave-field measurement of a suspended steel plate punctually loaded.

The dataset presented contains the experimental structural response, in the frequency domain, of a suspended steel plate to a point force excitation. The plate is excited by a mechanical point force generated by a Brüel & kJær shaker with a white noise signal input from 3.125 Hz to 2000 Hz.

Associations of perceived discrimination with health outcomes and health disparities in the cohort.

Objective: The goal of this study was to investigate the association of perceived discrimination with health outcomes and disparities.

Materials And Methods: The study cohort consists of 60,180 participants from the four largest SIRE groups in the Research Program participant body: Asian (1,291), Black (4,726), Hispanic (5,336), and White (48,827). A perceived discrimination index (PDI) was derived from participant responses to the "Social Determinants of Health" survey, and the Researcher Workbench was used to analyze associations and mediation effects of PDI and self-identified race and ethnicity (SIRE) with 1,755 diseases.

Increasing Representativeness in the Cohort Using Inverse Probability Weighting.

Large-scale population biobanks rely on volunteer participants, which may introduce biases that compromise the external validity of epidemiological studies. We characterized the volunteer participant bias for the Research Program cohort and developed a set of inverse probability (IP) weights that can be used to mitigate this bias. The cohort is older, more female, more educated, more likely to be covered by health insurance, less White, less likely to drink or smoke, and less healthy compared to the US population.

A composite socioeconomic deprivation index from survey data: associations with health outcomes and disparities.

Socioeconomic deprivation - defined as a lack of social, economic and material resources - is associated with poor health outcomes and health disparities between population groups. The Research Program is a longitudinal cohort study of diverse participants from the United States, with demographic and social determinants of health data gleaned from participant surveys and health outcome data derived from electronic health records. We developed a composite index of socioeconomic deprivation (iSDI) using a cohort of 202,919 participants - based on education, employment, health insurance, housing, and income data - and we associated iSDI with health outcomes and disparities.

Erratum to 'Long-Term Outcomes of the Knee and Hip Arthroplasties in Patients with Alkaptonuria' [Arthroplasty Today. Volume 6, Issue 4, December 2020, Pages 689-693].

[This corrects the article DOI: 10.1016/j.artd.

The complete mitochondrial genome of (Jordan & Snyder, 1901) (Ophidiiformes: Ophidiidae).

The genus is the most diverse group in the family Ophidiidae. In this study, we assembled and reported the complete mitochondrial genome of for the first time. The mitochondrial genome is 17,316 bp in length and contains 13 PCGs, 2 rRNAs, and 22 tRNAs.

Anatomic total shoulder arthroplasty in the 7th decade of life demonstrates superior long-term maintenance than in older patients.

Background: Anatomic total shoulder arthroplasty (aTSA) is often delayed due to concerns about a more rapid loss of postoperative improvements in younger, more active patients. This retrospective study investigated the effects of patient age on activity-specific functional outcomes at a minimum of 10 years following aTSA.

Methods: A retrospective review of a shoulder arthroplasty database was performed.

Validation of the Arabic Version of Asthma Numeracy Questionnaire (ANQ) Among Parents of Asthmatic Children: Factor and Rasch Analyses Study.

Background: The increasing global prevalence of asthma necessitates effective disease management, with patients and their families playing a central role. Enhancing health literacy (HL) among caregivers is critical to improving asthma outcomes.

Purpose: This study aimed to validate the Arabic version of the Asthma Numeracy Questionnaire (Ar-ANQ) to address the gap in HL assessment tools for Arabic-speaking populations.

Cerebrovascular reactivity and response times describe recent ischaemic symptomatology in patients with moyamoya.

Moyamoya is a non-atherosclerotic intracranial steno-occlusive condition that places patients at high risk for ischaemic stroke. Randomized trials of surgical revascularization demonstrating efficacy in ischaemic moyamoya have not been performed, and as such, biomarkers of parenchymal haemodynamic impairment are needed to assist with triage and evaluate post-surgical response. In this prospective study, we test the hypothesis that parenchymal cerebrovascular reactivity (CVR) metrics in response to a fixed-inspired 5% carbon dioxide challenge correlate with recent focal ischaemic symptoms.

Management of Recurrent Keratitis as a Complication of Black Scorpion Sting: A Case Report.

Scorpions are a group of arthropods known to be highly toxic to humans. We report the case of a previously healthy 61-year-old male who sustained a sting from an Androctonus crassicauda scorpion to his right eye. The patient was admitted to the intensive care unit (ICU) in a comatose state immediately after the sting.

Molecular diagnosis and phylogenetic analysis of a Middle East respiratory syndrome coronavirus human case in Jordan.

Middle East respiratory syndrome coronavirus (MERS-CoV) is an important zoonotic pathogen. The aim of this paper is to report one polymerase chain reaction (PCR)-positive case of MERS-CoV in a 27-year-old man who was involved in a nationwide longitudinal surveillance study of certain zoonotic diseases in Jordan including MERS-CoV. Whole-blood and nasal swab samples were collected from the man and five camels in the vicinity of his living area.

Epidemiology, transmission dynamics, risk factors, and future directions of rabies in the Arabian Peninsula using one health approach: a review.

Despite global initiatives to eliminate dog-mediated human rabies by 2030, the Arabian Peninsula faces challenges due to insufficient data. This review addresses the current rabies situation and knowledge gaps in the region and proposes One Health interventions. Employing a mixed-method approach combining scoping and systematic review, the study commenced with a Delphi discussion to identify knowledge gaps and set objectives.

4-Week intervention combining kiwifruit consumption and small-sided soccer games improves sleep quality in children with overweight/obesity and pre-existing sleep problems.

Childhood obesity is a global public health concern associated with various health risks, including disrupted sleep patterns. This study investigated the effects of kiwifruit consumption and small-sided soccer games (SSSG) over 4 weeks on sleep patterns in overweight/obese children with sleep problems. Thirty-six participants, aged 8 to 12 years with a body mass index above the 85th percentile, were randomly assigned to one of three groups: SSSG only ( = 12), SSSG-kiwifruit (SSSG-K,  = 12), or control (CG,  = 12).

Impact of Simulated Gastrointestinal Fluid: Viscosity, Surface Tension, and pH on the Dissolution and Rheology Assessment of Viscosity of Two Commercial Candesartan Cilexetil Products.

Objectives: The aim of this study was to ivnestigate the effect of simulated gastrointestinal viscosity, surface tension, and pH on the dissolution rate of two commercial candesartan cilexetil (CC) products.

Materials And Methods: dissolution of two commercial CC products and immediate release of 16 mg of CC were applied under two conditions: (1) the requirements of the United States Pharmacopeia (USP) and (2) conditions physiologically related to the gastrointestinal tract mimicking viscous food intake. The solubility of CC in different simulation fluids was also measured.

Understanding Nurses' perspectives on electronic health records in Egypt: Insights from a cross-sectional study.

Aim: This study aimed to evaluate the knowledge, attitudes, and acceptance of Electronic Health Records (EHRs) among nurses in Egypt.

Methods: A descriptive cross-sectional study was conducted involving 1217 nurses from 33 public and private hospitals. Data were collected using a self-administered online questionnaire, which assessed knowledge, attitudes, and acceptance of EHRs.

Advocacy in Action: International Patient Group Improves Hereditary Angioedema Diagnosis and Care Across the Asia-Pacific.

This study demonstrates that patient advocacy groups significantly enhance medication availability and improve diagnosis of hereditary angioedema (HAE), particularly in emerging economies within the Asia-Pacific region. This study supports integrating patient advocacy group involvement into management guidelines, emphasising their role in improving access to diagnostics and treatment for HAE.

Is there a relationship between lumbosacral epidural spinal injections and lumbosacral epidural lipomatosis? A retrospective study.

Background: We aim to investigate the potential association between the administration of Lumbosacral epidural steroid injections (LESIs) and the subsequent onset or progression of Lumbosacral epidural lipomatosis (LEL) in patients devoid of established risk factors for LEL.

Methods: We carried out a single-center retrospective study on patients who underwent LESI. We collected demographics including age and gender as well as clinical and radiological characteristics including the type of corticosteroids utilized, the number of LESIs administered, the use of epidural guidance during LESI procedures, and LEL grading.

Enhanced Recovery After Surgery for patients undergoing radical cystectomy: Surgeons' perspectives and recommendations ten years after its implementation.

Background And Objectives: Enhanced Recovery After Surgery (ERAS) guidelines for Radical Cystectomy (RC) were published over ten years ago. Aim of this systematic review is to update ERAS recommendations for patients undergoing RC and to give an expert opinion on the relevance of each single ERAS item.

Methods: A systematic review was performed to identify the impact of each single ERAS item on RC outcomes.

Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank.

Background And Aims: An in silico quantitative score of coronary artery disease (ISCAD), built using machine learning and clinical data from electronic health records, has been shown to result in gradations of risk of subclinical atherosclerosis, coronary artery disease (CAD) sequelae, and mortality. Large-scale metabolite biomarker profiling provides increased portability and objectivity in machine learning for disease prediction and gradation. However, these models have not been fully leveraged.

An investigation of antiproliferative and antioxidant properties of crude extracts from Sedum nicaeense All. (Crassulaceae).

This study evaluated the antioxidant and antiproliferative effects of aqueous, ethanolic and methanolic extracts of Sedum nicaeense flowers and leaves. The MTT assay assessed cytotoxicity against colorectal cancer cells (Caco-2, HCT-116), breast cancer cells (T47D, MCF-7) and normal fibroblasts (MRC-5), while the ferric-reducing antioxidant power (FRAP) assay measured antioxidant capacity. Essential oils from flowers and leaves were analyzed using gas chromatography-mass spectrometry (GC-MS).

Efficacy of non -thermal pressure plasma versus other modalities for disinfection of primary root canals.

Background: Endodontic treatment aims in the preservation of extremely carious primary teeth. For root canal therapy to be successful, root canals must be properly prepared and effectively irrigated .Therefore, it is necessary to select the proper root canal disinfection method to preserve the primary tooth.