436 results match your criteria: "Johns Hopkins Children's Center.[Affiliation]"

Introduction: Laparoscopic inguinal hernia repair (IHR) is being performed more frequently in children, but few studies have evaluated surgical practice patterns in infants. In this study, we surveyed pediatric surgeons within a regional consortium to assess current preferences for IHR strategy in infants. We hypothesized that early-career pediatric surgeons would prefer laparoscopic IHR over open IHR in this patient population.

View Article and Find Full Text PDF

As the Fontan population grows, understanding successful strategies for ventricular assist device (VAD) support of the failing Fontan circulation is needed. We performed a retrospective analysis of patients with Fontan circulation and systemic VAD support in the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry. Competing outcomes and Kaplan-Meier estimated survival methods were used.

View Article and Find Full Text PDF

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

View Article and Find Full Text PDF

Diazoxide-Associated Hyperglycemia: A Critical Case Precipitating Hyperosmolar Hyperglycemic State in a Child.

J Med Toxicol

January 2025

Division of Pediatric Emergency Medicine, Johns Hopkins Children's Center, 1800 Orleans Street, Baltimore, MD, 21287, USA.

Introduction: Diazoxide is the first-line treatment for children with hyperinsulinemic hypoglycemia (HI). In these cases, diazoxide raises blood glucose levels by suppressing insulin release, preventing hypoglycemia, and potentially devastating end-organ sequelae. Hyperosmolar hyperglycemic state (HHS) is an exceedingly rare side effect of diazoxide.

View Article and Find Full Text PDF
Article Synopsis
  • Sudden unexpected infant death (SUID), primarily from sudden infant death syndrome (SIDS), is a major cause of infant mortality, but there has been no focused study on SIDS content on YouTube despite its prevalence on platforms like Instagram and Twitter.
  • This observational study, conducted between December 2023 and January 2024, analyzed the top 100 SIDS-related videos on YouTube, identifying that most were produced by organizations, with a strong emphasis on risk factors and prevention measures.
  • The findings suggest the need for enhanced clinical and public health strategies to better utilize digital content to address SIDS risk factors and promote awareness, especially outside the United States, to ultimately reduce infant mortality rates worldwide.
View Article and Find Full Text PDF

Collaboration between registered dietitians and gastroenterologists in cystic fibrosis care: Results of an international cross-sectional survey.

Nutr Clin Pract

February 2025

Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Background: Collaboration between registered dietitians and gastroenterologists has not been evaluated in cystic fibrosis (CF). We surveyed registered dietitians and gastroenterologists regarding the current participation of gastroenterologists in CF centers and identified possible areas to enhance partnership between the two disciplines.

Methods: An anonymous online survey was distributed targeting registered dietitians and gastroenterologists involved in CF care through three international listservs (CF Nutrition, CF DIGEST, and PEDGI) over a 6-week period.

View Article and Find Full Text PDF
Article Synopsis
  • Short bowel syndrome (SBS) is a serious condition that can make people very sick, but adjusting how the intestines work can help improve health.
  • Researchers studied tiny samples of human intestines from mice with SBS to find out which genes are involved in how the intestines adapt.
  • They discovered that zinc can help SBS mice survive better and gain weight, and they think zinc could be a possible treatment for people with SBS too.
View Article and Find Full Text PDF

Rib-on-pelvis deformity: a modifiable driver of pain and poor health-related quality of life in cerebral palsy.

Spine Deform

January 2025

Department of Orthopaedics, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.

Article Synopsis
  • Cerebral Palsy (CP) patients often suffer from rib-on-pelvis deformity (ROP), leading to complications like pain and impaired breathing and balance, prompting this study to assess HRQOL before and after surgery in those with ROP.
  • A retrospective analysis involved 340 nonambulatory CP patients undergoing spinal fusion, finding that ROP patients had significantly worse preoperative HRQOL scores but showed greater improvement post-surgery compared to those without ROP.
  • The study concluded that having ROP negatively impacts preoperative HRQOL in CP patients, but these patients experience more substantial benefits following surgical intervention, particularly in areas related to comfort and mobility.
View Article and Find Full Text PDF

Objective: The care of critically ill neonatal and pediatric patients requiring transport is optimized by using specialty transport teams. Research demonstrates that training is best accomplished through routine simulation. At the project site, no simulation-based learning is provided to critical care transport team members.

View Article and Find Full Text PDF

Objective: To determine if mild-moderate hypertriglyceridemia (HTG) is associated with increased development of chronic pancreatitis (CP) or pancreatitis-associated complications in children with acute recurrent or CP.

Study Design: Longitudinal data from the INternational Study group of Pediatric Pancreatitis: In search for a cuRE-2 (INSPPIRE-2) cohort of children with acute recurrent or CP (n = 559) were analyzed. Subjects were divided into normal triglycerides (<150 mg/dL; 1.

View Article and Find Full Text PDF

Parental Perspectives From the Survey of Sleep Quality in the PICU Validation Study on Environmental Factors Causing Sleep Disruption in Critically Ill Children.

Crit Care Med

November 2024

Department of Pediatrics, Division of Pediatric Critical Care Medicine, University at Buffalo School of Medicine and Biomedical Sciences, John R. Oishei Children's Hospital, Buffalo, NY.

Article Synopsis
  • The study aimed to understand what factors disrupt children's sleep in Pediatric Intensive Care Units (PICUs) as reported by their parents.
  • A survey was conducted among parents in four PICUs and a pediatric sleep laboratory, with results indicating that 71% of children experienced significant sleep disruptions, primarily due to pain (38%) and lack of a home-like schedule (26%).
  • Findings suggest that critical care environments uniquely affect children's sleep, highlighting the need for tailored sleep promotion strategies in PICUs.
View Article and Find Full Text PDF

Background: The authors sought better outcomes for uncomplicated gastroschisis through development of clinical practice guidelines.

Methods: The authors and the American Pediatric Surgical Association Outcomes and Evidenced-based Practice Committee used an iterative process and chose two questions to develop clinical practice guidelines regarding (1) standardized nutrition protocols and (2) postnatal management strategies. An English language search of PubMed, MEDLINE, OVID, SCOPUS, and the Cochrane Library Database identified literature published between January 1, 1970, and December 31, 2019, with snowballing to 2022.

View Article and Find Full Text PDF

Objective: Screening, brief intervention, and referral to treatment (SBIRT) for adolescent alcohol and drug (AOD) use is recommended to occur with adolescents admitted to pediatric trauma centers. Most metrics on SBIRT service delivery only reference medical record documentation. In this analysis we examined changes in adolescents' perception of SBIRT services and concordance of adolescent-report and medical record data, among a sample of adolescents admitted before and after institutional SBIRT implementation.

View Article and Find Full Text PDF

Introduction: Patients with pectus excavatum (PE) often undergo cross-sectional imaging (CSI) to quantify severity for insurance authorization before surgical repair. The modified percent depth (MPD), an external caliper-based metric, was previously validated to be similar to the pectus index and correction index. This study explored family perceptions of CSI and MPD with respect to value and costs.

View Article and Find Full Text PDF

Neuroblastoma is the most common extracranial solid tumor diagnosed in children. This inaugural version of the NCCN Guidelines for Neuroblastoma provides recommendations for the diagnosis, risk classification, and treatment of neuroblastoma. The information in these guidelines was developed by the NCCN Neuroblastoma Panel, a multidisciplinary group of representatives with expertise in neuroblastoma, consisting of pediatric oncologists, radiologists, pathologists, surgeons, and radiation oncologists from NCCN Member Institutions.

View Article and Find Full Text PDF

Background: Pediatric trauma centers have had challenges meeting the American College of Surgeons criteria for screening and intervening for alcohol with adolescent trauma patients. The study objective was to conduct an implementation trial to evaluate the effectiveness of the Science to Service Laboratory (SSL) implementation strategy in improving alcohol and other drugs (AOD) screening, brief intervention, and referral to treatment (SBIRT) delivery at pediatric trauma centers.

Methods: Using a stepped wedge cross-over cluster randomized design, 10 US pediatric trauma centers received the SSL implementation strategy to deliver SBIRT with admitted adolescent (12-17 years old) trauma patients.

View Article and Find Full Text PDF

Communicating with Parents About Therapeutic Hypothermia and Hypoxic Ischemic Encephalopathy: Integrating a Palliative Care Approach into Practice.

Clin Perinatol

September 2024

Division of Pediatric Neurology and Developmental Medicine, Department of Pediatrics, Duke University School of Medicine, DUMC 3936, Durham 27710, USA; Division of Pediatric Neurology and Developmental Medicine, Department of Population Health Sciences, Duke University School of Medicine, DUMC 3936, Durham 27710, USA.

Parents of newborns with hypoxic ischemic encephalopathy (HIE) can face communication challenges in the neonatal intensive care unit. Both specialty palliative care and primary palliative care trained clinicians can assist parents as they navigate traumatic experiences and uncertain prognoses. Using evidence-based frameworks, the authors provide samples of how to communicate with parents and promote parent well-being across the care trajectory.

View Article and Find Full Text PDF

Importance: The indications, safety, and efficacy of chemical venous thromboembolism prophylaxis (cVTE) in pediatric trauma patients remain unclear. A set of high-risk criteria to guide cVTE use was recently recommended; however, these criteria have not been evaluated prospectively.

Objective: To examine high-risk criteria and cVTE use in a prospective multi-institutional study of pediatric trauma patients.

View Article and Find Full Text PDF

[This corrects the article DOI: 10.3389/fped.2024.

View Article and Find Full Text PDF

Artiss fibrin sealant for the fixation of autografts in pediatric burn care.

Burns

September 2024

Johns Hopkins Children's Center, Department of Pediatric Surgery, 1800 Orleans St, Baltimore, MD 21287, USA. Electronic address:

Background: Traditional fixation of autografts in the treatment of burns involves the use of sutures and staples. A novel fibrin sealant, Artiss, has been introduced as an alternate method of fixation and has shown promising safety and efficacy results in the adult population. Our study assessed the effectiveness of fibrin sealant to secure autologous split thickness skin grafts (ASTSG) in the pediatric burn population.

View Article and Find Full Text PDF