839 results match your criteria: "John Paul II Catholic University[Affiliation]"
Biomolecules
September 2024
Department of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego 8B Str., 20-090 Lublin, Poland.
Kynurenic acid (KYNA) is a metabolite of tryptophan formed on the kynurenine pathway. Its pharmacological effects are relatively well characterized in mammals, whereas its role in fish is poorly understood. Therefore, the aim of the study was to expand the knowledge of KYNA's presence inside a fish's body and its impact on fish development and function.
View Article and Find Full Text PDFDrug Discov Today
November 2024
Department of Twin Research, King's College London, London, UK; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:
The use of proteomics in human studies investigating stroke and myocardial infarction (MI) has been increasing, prompting a review of the literature. This revealed proteinaceous biomarkers of stroke from thrombi, brain tissue, cells, and particles, some of which cross the blood-brain barrier (BBB). Several proteins were also implicated in coronary artery disease (CAD), which often underlies MI, cholesterol transportation, and inflammation.
View Article and Find Full Text PDFFood Chem
January 2025
Department of Chemistry, Institute of Biological Sciences, Faculty of Medicine, Collegium Medicum, The John Paul II Catholic University of Lublin, Konstantynów 1J, 20-708 Lublin, Poland. Electronic address:
In this work, new sorbents for the purification of anthocyanin-rich extracts were evaluated. Copolymers of 4-vinylpyridine crosslinked with trimethylolpropane trimethacrylate (poly(4VP-co-TRIM)) or 1,4-dimethacryloyloxybenzene (poly(4VP-co-14DMB)) were tested for their potential to capture polyphenols. Copolymers were obtained by seed swelling polymerization in the form of microspheres with permanent porous structure - attractive features of sorbents used for sample purification by dispersive solid phase extraction.
View Article and Find Full Text PDFSci Rep
September 2024
Institute of Psychology, John Paul II Catholic University of Lublin, Lublin, Poland.
The article raises the issue of the quality of life (QoL) of adolescents during the COVID-19 pandemic, its relationships with coping and mediating role of the received social support (RSS). The nationwide survey was conducted from September 13, 2021 to October 1, 2021. The total of 4970 individuals aged 10-18 years old were researched in Poland.
View Article and Find Full Text PDFMolecules
September 2024
Department of Biochemistry and Molecular Biology, Medical University of Lublin, 20-093 Lublin, Poland.
Front Public Health
September 2024
Institute of Sociological Sciences, John Paul II Catholic University of Lublin, Lublin, Poland.
The study aimed to determine whether self-efficacy acts as a moderator between the severity of menopausal symptoms and life satisfaction. The research tools were: The Generalized Self-Efficacy Scale (GSES), The Satisfaction with Life Scale (SWLS) The Menopause - Specific Quality of Life (MENQOL), and a standardized questionnaire comprising questions on the participants' characteristics. 516 women using health care services who had menopausal symptoms took part in the study.
View Article and Find Full Text PDFJ Adv Nurs
September 2024
Department of Holistic Care and Management in Nursing, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland.
Aim: To assess the level of stress of conscience experienced by Polish nurses and midwives and its determinants.
Design: Descriptive cross-sectional study.
Methods: The study was conducted from March 2019 to December 2020 and included convenience sampling of nurses and midwives working in hospitals in south-eastern Poland.
Intensive Care Med
December 2024
Department of Clinical Research and Development, LUXMED Group Postępu 21C, Warsaw, Poland.
Ecotoxicol Environ Saf
October 2024
Nicholaus Copernicus University, Collegium Medicum in Bydgoszcz, Department of Medical Biology and Biochemistry, M. Karłowicz St. 24, Bydgoszcz PL 85-092, Poland. Electronic address:
Male infertility is a world multifactorial problem modulated by environmental and genetic factors. Male aspects account for 20-50 % of infertility cases. Our results are unique because they treat the importance of components participating in the determination of male infertility (environmental and immunogenetic determinants, seminological analysis, lipoperoxidation, genetic determinants, role of aluminum, arsenic, cadmium and boron).
View Article and Find Full Text PDFInt J Mol Sci
August 2024
Department of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
Alzheimer's disease (AD) is characterized by, among other things, dementia and a decline in cognitive performance. In AD, dementia has neurodegenerative features and starts with mild cognitive impairment (MCI). Research indicates that apoptosis and neuronal loss occur in AD, in which oxidative stress plays an important role.
View Article and Find Full Text PDFInt J Mol Sci
August 2024
Department of Clinical Pharmacy and Pharmaceutical Care, Medical University of Lublin, Chodźki Street 7, 20-093 Lublin, Poland.
Omega-3 polyunsaturated fatty acids have received considerable attention in the field of mental health, in particular regarding the treatment of depression. This review presents an overview of current research on the role of omega-3 fatty acids in the prevention and treatment of depressive disorders. The existing body of evidence demonstrates that omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have antidepressant effects that can be attributed to their modulation of neuroinflammation, neurotransmitter function, and neuroplasticity.
View Article and Find Full Text PDFJ Relig Health
December 2024
Institute of Psychology, The John Paul II Catholic University of Lublin, Al. Raclawickie 14, 20-950, Lublin, Poland.
Religious struggles tend noticeably to influence the sphere of social well-being in emerging adulthood as individuals modify their religious beliefs and practices, form personal identity patterns, and rediscover new life purpose and values. The aim of the current study was to investigate whether meaning-making and meaning in life (presence and search) can serially mediate the hypothesized links between religious comfort vs. strain and social well-being.
View Article and Find Full Text PDFInt J Psychol
December 2024
Institute of Psychology, University of Bologna, Bologna, Italy.
Facebook is one of the most popular social networking sites. However, Facebook intrusion or addiction is a growing concern as it involves an excessive attachment to Facebook, which disrupts daily functioning. To date, few studies have examined whether cross-cultural differences in the measurement of Facebook addiction exist.
View Article and Find Full Text PDFJ Exp Child Psychol
November 2024
Institute of Psychology, Faculty of Social Sciences, The John Paul II Catholic University of Lublin, 20-950 Lublin, Poland.
Some students suffer from math anxiety and experience negative emotions in mathematics education. Children's math anxiety is negatively related to their math achievement, suggesting that math anxiety puts their math learning at risk. Several theoretical accounts have been proposed that help to explain this association between math anxiety and achievement.
View Article and Find Full Text PDFChemMedChem
December 2024
Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
A novel library of naphthoquinone derivatives (3-5 aa) was synthesized and evaluated for their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v demonstrated superior cytotoxic activity against the cancer cell lines that were studied. All the studied compounds exhibited a higher selectivity index (SI) and a favourable safety profile than the standard drug doxorubicin.
View Article and Find Full Text PDFSci Rep
August 2024
Department of Chemistry, Institute of Biological Sciences, Faculty of Medicine, the John Paul II Catholic University of Lublin, Konstantynów 1J, 20-708, Lublin, Poland.
Purpose: This study aims to adapt and verify the psychometric properties of the Craving for Internet Gaming Scale (CIGS) in a Polish sample. Craving, although observed as significantly associated with Internet Gaming Disorder, is not currently included in its diagnostic criteria. This research addresses the need for scales to measure craving in this particular context.
View Article and Find Full Text PDFBMC Pediatr
August 2024
Institute of Medical Science, John Paul II Catholic University of Lublin, Lublin, Poland.
J Pediatr
December 2024
Institute of Psychology, The John Paul II Catholic University of Lublin, Lublin, Poland. Electronic address:
Skinmed
August 2024
Chair of Ophthalmology, University of Warmia and Mazury, Warsaw, Poland.
Background: In the context of discussions between supporters and opponents of euthanasia, and legal regulations regarding this type of practices, the attitude of young people with respect to this phenomenon is a very interesting issue. According to Polish law, euthanasia is prohibited. The aim of this study was to determine the degree of acceptance of euthanasia among students from Polish universities across three different fields of study: psychology, medicine, and economic-technical disciplines, and to identify the factors associated with the acceptance of this phenomenon.
View Article and Find Full Text PDFPlant Reprod
December 2024
Department of Plant Physiology and Biophysics, Institute of Biological Sciences, Maria Curie-Skłodowska University, 20-033, Lublin, Poland.
Lipoxygenase activity and localization vary throughout the development of Larix kaempferi ovules, with the highest enzyme activity observed in ovules at the cellular stage and the most intense immunogold reaction noted at the mature archegonium stage of gametophyte development. Lipoxygenases are a family of oxidoreductases with a significant role in biological systems, widespread in living organisms e.g.
View Article and Find Full Text PDFPsychoneuroendocrinology
October 2024
Department of Psychology, University of Warsaw, ul. Stawki 5/7, Warsaw 00-183, Poland.
Objective: The stress experienced by a woman during pregnancy not only has a negative impact on her well-being and physical health but also adversely affects the fetus. Stress is strongly linked with time perspective, defined as the tendency to focus on the past, present, or future. The study aimed to investigate how couples' balanced time perspective was related to maternal prenatal hair cortisol concentration and perceived stress in the first and third trimesters of pregnancy.
View Article and Find Full Text PDFMolecules
June 2024
Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.
Heterocyclic compounds, particularly those containing azole rings, have shown extensive biological activity, including anticancer, antibacterial, and antifungal properties. Among these, the imidazole ring stands out due to its diverse therapeutic potential. In the presented study, we designed and synthesized a series of imidazole derivatives to identify compounds with high biological potential.
View Article and Find Full Text PDFFront Microbiol
June 2024
Laboratory of Research and Nature Protection, Krzczonów, Poland.
Introduction: Global warming affects air and water temperatures, which impacts the phenology of lakes and aquatic ecosystems. These changes are most noticeable during winter, when the potentially toxic forms its inoculum for annual blooms. Mostly, research has been conducted on alpine lakes, where blooms have persisted for decades, while a few have focused on temperate lakes.
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