Proteins in human body fluids contain in vivo antigen analog of the melibiose-derived glycation product: MAGE.

Melibiose-derived AGE (MAGE) is an advanced glycation end-product formed in vitro in anhydrous conditions on proteins and protein-free amino acids during glycation with melibiose. Our previous studies revealed the presence of MAGE antigen in the human body and tissues of several other species, including muscles, fat, extracellular matrix, and blood. MAGE is also antigenic and induces generation of anti-MAGE antibody.

The level of spiritual care competence of Polish nurses and the psychometric properties of the spiritual care competence scale (SCCS).

Background: Providing effective spiritual nursing care requires development of professional competence which, when regularly evaluated, allows one to direct undergraduate and postgraduate nursing education in order to develop knowledge, skills and attitudes of nurses in the scope of spiritual care.

Aim: The aim of this study was to analyse the level of spiritual competence of professionally active nurses in Poland and, additionally, to analyse the psychometric properties of the Spiritual Care Competence Scale (SCCS).

Methods: A cross-sectional study among Polish nurses (n = 343) was performed in accordance with the STrengthening the Reporting of OBservational studies in Epidemiology guidelines.

Development of novel spectroscopic and machine learning methods for the measurement of periodic changes in COVID-19 antibody level.

In this research, blood samples of 47 patients infected by COVID were analyzed. The samples were taken on the 1st, 3rd and 6th month after the detection of COVID infection. Total antibody levels were measured against the SARS-CoV-2 N antigen and surrogate virus neutralization by serological methods.

The Effect of Sintering Temperature on the Phase Composition, Microstructure, and Mechanical Properties of Yttria-Stabilized Zirconia.

It is known that the yttria-stabilized zirconia (YSZ) material has superior thermal, mechanical, and electrical properties. This material is used for manufacturing products and components of air heaters, hydrogen reformers, cracking furnaces, fired heaters, etc. This work is aimed at searching for the optimal sintering mode of YSZ ceramics that provides a high crack growth resistance.

Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline.

The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer.

Blindfolded adults use mental transformation strategies for spatial scaling of tactile maps.

The current study tested strategies of spatial scaling in the haptic domain. Blindfolded adults (N = 31, aged 20-24 years) were presented with an embossed graphic including a target and asked to encode a target location on this map, imagine this map at a given scale, and to localize a target at the same spot on an empty referent space. Maps varied in three different sizes whereas the referent space had a constant size, resulting in three different scaling factors (1:1, 1:2, 1:4).

Nanozymes with reductase-like activities: antioxidant properties and electrochemical behavior.

Nanozymes (NZs) as stable cost-effective mimics of natural enzymes may be promising catalysts in food and environmental biotechnology, biosensors, alternative energy and medicine. The majority of known NZs are mimetics of oxidoreductases, although there are only limited data regarding mimetics of reductases. In the present research, a number of metal-based NZs were synthesized chemical methods and screened for their antioxidant ability in solution.

Phytoplankton Composition and Ecological Status of Lakes with Cyanobacteria Dominance.

Phytoplankton is one of the five biological quality elements used in the assessment of the ecological status of surface waters according to the European Water Framework Directive established in 2000. In this study, we determined the ecological status of three small and shallow lakes in the Polesie Plain, Eastern Poland, by using indices based on phytoplankton assemblages. The predominant phytoplankton of all three lakes were filamentous cyanobacteria, both heterocystous and non-heterocystous, represented by the genera , , and .

as an Alternative and Valuable Source of Nutritional and Bioactive Compounds for Humans.

Yarrowia lipolytica, an oleagineous species of yeast, is a carrier of various important nutrients. The biomass of this yeast is an extensive source of protein, exogenous amino acids, bioavailable essenctial trace minerals, and lipid compounds as mainly unsaturated fatty acids. The biomass also contains B vitamins, including vitamin B12, and many other bioactive components.

Adjustment in women treated for rheumatoid arthritis.

Introduction: The favourable or unfavourable process of a patient's adaptation to a challenging medical condition may indicate that certain adjustment reactions, which can be either constructive or undesirable, tend to prevail.

Objective: The aim of the study was to examine the adjustment reactions of patients, and to define the correlation between the reactions and socio-demographic factors, health self-assessment, satisfaction with medical care, duration of treatment, and limitations in women treated for rheumatoid arthritis.

Material And Methods: The study was conducted at the Department of Rheumatology and Connective Tissue Diseases and the Specialist Outpatient Clinic of the Independent Public Teaching Hospital No.

PTSD as a Moderator of the Relationship Between the Distribution of Personal Resources and Spiritual Change Among Participants of Hostilities in Ukraine.

The theory of conservation of resources (COR) can be used to search for mechanisms that explain spiritual changes caused by trauma. The present study aimed to verify whether PTSD could be a potential moderator between the distribution of personal resources and spiritual changes. The study included a total of 324 adults (75 women and 243 men) aged 18-74.

Designing Robots for Elderly from the Perspective of Potential End-Users: A Sociological Approach.

The proposed research aims to investigate the problem of age-friendly robot designing from the perspective of the potential end-users. The initial objectives addressed three main issues: how the elderly envision robots and their knowledge on technological development; age-friendly robot design; the elderly's involvement in the robot design process. The empirical material analyzed are the results of in-depth interviews with people aged 70+.

Comparative Nanopore Sequencing-Based Evaluation of the Midgut Microbiota of the Summer Chafer ( L.) Associated with Possible Resistance to Entomopathogenic Nematodes.

Root-feeding larvae and certain other scarab beetles are the main soil-dwelling pests found in Europe, while entomopathogenic nematodes (EPN) have been used as a biocontrol agent against these species. Our study provides the first detailed characterization of the bacterial community of the midgut in wild larvae, based on the nanopore sequencing of the 16S rRNA gene. In the whole dataset, we detected 2586 different genera and 11,641 species, with only 83 diverse bacterial genera shared by all studied individuals, which may represent members of the core midgut microbiota of larvae.

Titles and Semantic Violations Affect Eye Movements When Viewing Contemporary Paintings.

The role of titles in perception of visual art is a topic of interesting discussions that brings together artists, curators, and researchers. Titles provide contextual cues and guide perception. They can be particularly useful when paintings include semantic violations that make them challenging for viewers, especially viewers lacking expert knowledge.

The influence of Facebook intrusion and task context on cognitive control.

Social networking sites, especially Facebook, have become increasingly popular over the past decades. However, besides the benefits of using Facebook, negative effects in the form of Facebook intrusion are also increasingly pointed out. Much of the research focuses on personality, emotional and social factors related to Facebook intrusion.

Are they ready? Moderators of the correlation between work affect and job satisfaction felt by teachers of inclusive and special schools.

Background: The study aimed to determine to what extent emotions experienced at work are predictors of the level of teachers' job satisfaction. The moderating role of the type of school - inclusive and special - for this correlation was also analysed.

Participants And Procedure: The study involved 214 teachers at three levels of inclusive and special schools (primary, middle and high) attended by pupils with special educational needs.

Relationship between Socio-Demographic Factors and Posttraumatic Stress Disorder: A Cross Sectional Study among Civilian Participants' Hostilities in Ukraine.

Background: Even though there is an extensive body of literature on posttraumatic stress disorder (PTSD) in individuals who have experienced armed conflict, there are still many grey areas, especially in relation to civilian participants in hostilities. This article evaluates how socio-demographic factors and the interactions between them have influenced PTSD among civilians involved in the recent war in Ukraine.

Methods: This cross-sectional study included a convenience sample of 314 adults, 74 women, and 235 men.

Associations between the Willingness to Donate Samples to Biobanks and Selected Psychological Variables.

Over the past few decades, there has been a dynamic development of biobanks collecting human biological material and data. Advances in biomedical research based on biobanks, however, are highly dependent on the successful enrolment and participation of human subjects. Therefore, it is crucial to recognise those factors affecting the willingness of individuals to participate in biomedical research.

MSCs as Tumor-Specific Vectors for the Delivery of Anticancer Agents-A Potential Therapeutic Strategy in Cancer Diseases: Perspectives for Quinazoline Derivatives.

Mesenchymal stem cells (MSCs) are considered to be a powerful tool in the treatment of various diseases. Scientists are particularly interested in the possibility of using MSCs in cancer therapy. The research carried out so far has shown that MSCs possess both potential pro-oncogenic and anti-oncogenic properties.

Promiscuous Lipase-Catalyzed Markovnikov Addition of H-Phosphites to Vinyl Esters for the Synthesis of Cytotoxic α-Acyloxy Phosphonate Derivatives.

An enzymatic route for phosphorous-carbon- bond formation is developed by discovering new promiscuous activity of lipase. This biocatalytic transformation of phosphorous-carbon- bond addition leads to biologically and pharmacologically relevant α-acyloxy phosphonates with methyl group in α-position. A series of target compounds were synthesized with yields ranging from 54% to 83% by enzymatic reaction with (CcL) lipase via Markovnikov addition of -phosphites to vinyl esters.

"Personality in prison uniform". The influence of personality on building work engagement, applying job crafting strategies and well-being among prison officers.

Background: Numerous studies have been devoted to analyzing the negative effects of occupational stress on the mental health of prison officers. Less attention is paid to positive mechanisms, as postulated by positive psychology. The aim of the study was to examine the relationship between personality traits and the strategies used by prison officers to build engagement, and professional well-being by adjusting the workplace to their strengths, skills and professional preferences.

Development of Sulfamoylated 4-(1-Phenyl-1-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer.

We present here the advances achieved in the development of new sulfamoylated 4-(1-phenyl-1-1,2,3-triazol-4-yl)phenol derivatives as potent steroid sulfatase (STS) inhibitors for the treatment of breast cancer. Prompted by promising biological results and in silico analysis, the initial series of similar compounds were extended, appending a variety of m-substituents at the outer phenyl ring. The inhibition profiles of the newly synthesized compounds were evaluated using a radioisotope enzymatic assay and, together with the preceding reported derivatives, using a radioisotope assay in MCF-7 cells.

The Current State of Knowledge on and (Chia Seeds).

Chia seeds () are obtained from L. This raw material is distinguished by its rich chemical composition and valuable nutritional properties. It is currently referred to as "health food".