Reactive Noble-Gas Compounds Explored by 3D Electron Diffraction: XeF-MnF Adducts and a Facile Sample Handling Procedure.

Recent advances in 3D electron diffraction (3D ED) have succeeded in matching the capabilities of single-crystal X-ray diffraction (SCXRD), while requiring only submicron crystals for successful structural investigations. One of the many diverse areas to benefit from the 3D ED structural analysis is main-group chemistry, where compounds are often poorly crystalline or single-crystal growth is challenging. A facile method for loading and transferring highly air-sensitive and strongly oxidizing samples at low temperatures to a transmission electron microscope (TEM) for 3D ED analysis was successfully developed and tested on xenon(II) compounds from the XeF-MnF system.

Effect of Zn-substitution on magnetic structure of cobalt ferrite nanoparticles.

This study investigates the effects of Zn substitution on the magnetic properties of ∼5 nm cobalt ferrite nanoparticles (ZnxCo1-xFe2O4, where x = 0, 0.13, 0.34, and 0.

Enhancement of the Piezocatalytic Response of La-Doped BiFeO Nanoparticles by Defects Synergy.

Because of their intrinsic polarization and related properties, ferroelectrics attract significant attention to address energy transformation and environmental protection. Here, by using trivalent-ion-lanthanum doping of BiFeO nanoparticles (NPs), it is shown that defects and piezoelectric potential are synergized to achieve a high piezocatalytic effect for decomposing the model Rhodamine B (RhB) pollutant, reaching a record-high piezocatalytic rate of 21 360 L mol min (i.e.

Assessing the Quality of Solvent-Assisted Lipid Bilayers Formed at Different Phases and Aqueous Buffer Media: A QCM-D Study.

Supported lipid bilayers (SLBs) are low-complexity biomimetic membranes, serving as popular experimental platforms to study membrane organization and lipid transfer, membrane uptake of nanoparticles and biomolecules, and many other processes. Quartz crystal microbalance with dissipation monitoring has been utilized to probe the influence of several parameters on the quality of SLBs formed on Au- and SiO-coated sensors. The influence of the aqueous medium (i.

Lysosomal Proteases and Their Inhibitors.

The discovery of the lysosome, a major cytoplasmic organelle, represents a breakthrough in the understanding of intracellular protein degradation processes-proteolysis [...

Associations between Urinary Phthalate Metabolites with BDNF and Behavioral Function among European Children from Five HBM4EU Aligned Studies.

Based on toxicological evidence, children's exposure to phthalates may contribute to altered neurodevelopment and abnormal regulation of brain-derived neurotrophic factor (BDNF). We analyzed data from five aligned studies of the Human Biomonitoring for Europe (HBM4EU) project. Ten phthalate metabolites and protein BDNF levels were measured in the urine samples of 1148 children aged 6-12 years from Italy (NACII-IT cohort), Slovakia (PCB-SK cohort), Hungary (InAirQ-HU cohort) and Norway (NEBII-NO).

Nanocomposite Hydrogels from Nanodiamonds and a Self-Assembling Tripeptide.

We report the successful assembly of a tripeptide in the presence of nanodiamonds (NDs) into nanocomposite hydrogels. While the presence of NDs does not hinder peptide self-assembly and gelation kinetics are not affected, NDs improve the viscoelastic properties and significantly increase the elastic moduli of the peptide hydrogels. Increased resistance of the gels against applied stress can also be attained depending on the amount of NDs loaded in the nanocomposite.

A longitudinal multi-modal dataset for dementia monitoring and diagnosis.

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset. The analysis of speech and language has emerged as a promising and non-intrusive technology to diagnose and monitor dementia.

Exogenous ketosis attenuates acute mountain sickness and mitigates normobaric high-altitude hypoxemia.

Acute mountain sickness (AMS) represents a considerable issue for individuals sojourning to high altitudes with systemic hypoxemia known to be intimately involved in its development. Based on recent evidence that ketone ester (KE) intake attenuates hypoxemia, we investigated whether exogenous ketosis might mitigate AMS development and identified underlying physiological mechanisms. Fourteen healthy, male participants were enrolled in two 29-h protocols (simulated altitude of 4,000-4,500 m) receiving either KE or a placebo (CON) at regular timepoints throughout the protocol in a randomized, crossover manner.

Scalable Solid-State Synthesis of Carbon-Supported Ir Electrocatalysts for Acidic Oxygen Evolution Reaction: Exploring the Structure-Activity Relationship.

Enhancing iridium (Ir)-based electrocatalysts to achieve high activity and robust durability for the oxygen evolution reaction (OER) in acidic environments has been an ongoing mission in the commercialization of proton exchange membrane (PEM) electrolyzers. In this study, we present the synthesis of carbon-supported Ir nanoparticles (NPs) using a modified impregnation method followed by solid-state reduction, with Ir loadings of 20 and 40 wt % on carbon. Among the catalysts, the sample with an Ir loading of 20 wt % synthesized at 1000 °C with a heating rate of 300 °C/h demonstrated the highest mass-normalized OER performance of 1209 A g and an OER current retention of 80% after 1000 cycles of cyclic voltammetry (CV).

Combination of Searches for Higgs Boson Pair Production in pp Collisions at sqrt[s]=13 TeV with the ATLAS Detector.

This Letter presents results from a combination of searches for Higgs boson pair production using 126-140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV recorded with the ATLAS detector. At 95% confidence level (CL), the upper limit on the production rate is 2.9 times the standard model (SM) prediction, with an expected limit of 2.

Studies of the Energy Dependence of Diboson Polarization Fractions and the Radiation-Amplitude-Zero Effect in WZ Production with the ATLAS Detector.

This Letter presents the first study of the energy dependence of diboson polarization fractions in WZ→ℓνℓ^{'}ℓ^{'}(ℓ,ℓ^{'}=e,μ) production. The dataset used corresponds to an integrated luminosity of 140  fb^{-1} of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the ATLAS detector. Two fiducial regions with an enhanced presence of events featuring two longitudinally polarized bosons are defined.

An elevated rate of whole-genome duplications in cancers from Black patients.

In the United States, Black individuals have higher rates of cancer mortality than any other racial group. Here, we examine chromosome copy number changes in cancers from more than 1800 self-reported Black patients. We find that tumors from self-reported Black patients are significantly more likely to exhibit whole-genome duplications (WGDs), a genomic event that enhances metastasis and aggressive disease, compared to tumors from self-reported white patients.

Exploring Kleefstra syndrome cohort phenotype characteristics: Prevalence insights from caregiver-reported outcomes.

Kleefstra syndrome (KLEFS1) is a rare genetic neurodevelopmental disorder affecting multiple body systems. It continues to be under-researched, and its prevalence remains unknown. This paper builds on the international KLEFS1 cohort of 172 individuals based on the caregiver-reported outcomes collected within the online data collection platform GenIDA and reports the occurrence, frequency and severity of symptoms in KLEFS1.

Steepness-fragility insights from the temperature derivative analysis of dielectric data of a highly nonsymmetric liquid crystal dimer.

A comprehensive dynamic analysis of the dielectric relaxation-time data across a broad temperature range for both isotropic and nematic phases has been conducted on the CBO3O.Py liquid crystal dimer, the shorter chain-length compound within the highly nonsymmetric pyrene-based series of liquid crystal dimers (CBOnO.Py, with n ranging from 3 to 11).

Bridging the Gap: A Comparative Analysis of Healthcare Quality Perceptions Between the Older People and Healthcare Providers.

In our study aimed at improving the healthcare system for the aging population, we compared healthcare quality evaluations between 96 older individuals and 30 healthcare providers in Split-Dalmatia County (Croatia). Using nonparametric analyses such as the Mann-Whitney and Wilcoxon tests on Likert scale questionnaire scores, we found most participants highlighted challenges such as healthcare affordability, long wait times, reliance on private care, poor public transportation, and insufficient rural healthcare services. Healthcare providers rated these quality indicators even more negatively.

Zero-shot evaluation of ChatGPT for food named-entity recognition and linking.

Introduction: Recognizing and extracting key information from textual data plays an important role in intelligent systems by maintaining up-to-date knowledge, reinforcing informed decision-making, question-answering, and more. It is especially apparent in the food domain, where critical information guides the decisions of nutritionists and clinicians. The information extraction process involves two natural language processing tasks named entity recognition-NER and named entity linking-NEL.

Role of quantitative imaging biomarkers in an early FDG-PET/CT for detection of immune-related adverse events in melanoma patients: a prospective study.

Background: To evaluate the role of the novel quantitative imaging biomarker (QIB) SUV of F-FDG uptake extracted from early F-FDG-PET/CT scan at 4 weeks for the detection of immune-related adverse events (rAE) in a cohort of patients with metastatic melanoma (mM) patients receiving immune-checkpoint inhibitors (ICI).

Patients And Methods: In this prospective non-interventional, one-centre clinical study, patients with mM, receiving ICI treatment, were regularly followed by F-FDG PET/CT. Patients were scanned at baseline, early point at week four (W4), week sixteen (W16) and week thirty-two (W32) after ICI initiation.

Analysis of magnetic resonance contrast agent entrapment following reversible electroporation .

Background: Administering gadolinium-based contrast agent before electroporation allows the contrast agent to enter the cells and enables MRI assessment of reversibly electroporated regions. The aim of this study was evaluation of contrast agent entrapment in Chinese hamster ovary (CHO) cells and comparison of these results with those determined by standard methods for assessing cell membrane permeability, cell membrane integrity and cell survival following electroporation.

Materials And Methods: Cell membrane permeabilization and cell membrane integrity experiments were performed using YO-PRO-1 dye and propidium iodide, respectively.

Geochemical fingerprinting of Norway spruce from the Eastern Carpathians: Sr isotopic and multi-elemental signatures.

Ensuring efficient wood traceability within procurement chains is essential for establishing sustainable forest management and minimizing environmental damage in countries that produce and export timber. While some progress has been made with key legislative reforms to tackle this issue, the effectiveness of law enforcement still relies on the availability of appropriate analytical tools to determine the provenance of wood. This study documents the Sr isotopic and multi-elemental signatures of Norway spruce trees in the Eastern Carpathians, Romania - an area known for intensive forest logging.

Plasma Treatment of Nanocellulose to Improve the Surface Properties.

Nanocellulose is among the most promising materials for enhancing the mechanical properties of polymer composites. Broad application is, however, limited by inadequate surface properties. A standard technique for tailoring the surface composition and wettability of polymers is a brief treatment with non-equilibrium gaseous plasma, but it often fails when treating materials with a large surface-to-mass ratio, such as cellulose nanofibers.

Correction: Trstenjak Prebanda et al. Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages. 2019, , 1476.

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Design Optimisation of a Flat-Panel, Limited-Angle TOF-PET Scanner: A Simulation Study.

In time-of-flight positron emission tomography (TOF-PET), a coincidence time resolution (CTR) below 100 ps reduces the angular coverage requirements and, thus, the geometric constraints of the scanner design. Among other possibilities, this opens the possibility of using flat-panel PET detectors. Such a design would be more cost-accessible and compact and allow for a higher degree of modularity than a conventional ring scanner.

Nanocarbon-Polymer Composites for Next-Generation Breast Implant Materials.

Most breast implants currently used in both reconstructive and cosmetic surgery have a silicone outer shell, which, despite much progress, remains susceptible to mechanical failure, infection, and foreign body response. This study shows that the durability and biocompatibility of breast implant-grade silicone can be enhanced by incorporating carbon nanomaterials of sp and sp hybridization into the polymer matrix and onto its surface. Plasma treatment of the implant surface can be used to modify platelet adhesion and activation to prevent thrombosis, postoperative infection, and inflammation disorders.