8 results match your criteria: "Jinshan Hospital Fudan University[Affiliation]"
The Efficacy of Curcumin Application to Melanoma in Mice: A Systematic Review and Meta-analysis.
Ann Plast Surg
August 2024
Department of Plastic and Reconstructive Surgery, Zhongshan Hospital Fudan University, Shanghai, People's Republic of China.
Objective: Melanoma is a skin tumor that poses a serious threat to human health. Our study explores the effectiveness and safety of curcumin in the treatment of melanoma based on animal models, and providing evidence-based medical evidence for curcumin in the treatment of malignant melanoma.
Methods: The study collected all randomized controlled trial data from the establishment of the database to October 2023 of curcumin for the treatment of melanoma in mice by searching PubMed, Embase, and the Cochrane Library.
Background The endothelium is essential for maintaining vascular physiological homeostasis and the endothelial injury leads to the neointimal hyperplasia because of the excessive proliferation of vascular smooth muscle cells. Endothelial Foxp1 (forkhead box P1) has been shown to control endothelial cell (EC) proliferation and migration in vitro. However, whether EC-Foxp1 participates in neointimal formation in vivo is not clear.
View Article and Find Full Text PDFA stricter control of low-density lipoprotein is necessary for thrombosis reduction in "lower thrombosis risk" patients with atrial fibrillation: a multicenter retrospective cohort study.
J Thromb Thrombolysis
November 2020
Department of Cardiology, Huashan Hospital Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Article Synopsis
- Atrial fibrillation (AF) patients have a higher chance of forming blood clots, and a study found that low-density lipoprotein cholesterol (LDL-C) levels can predict this risk.
- The research followed AF patients for 26 months, dividing them into low-risk and high-risk groups based on their CHADSVASc score to see how LDL-C affected their likelihood of thrombosis.
- Results showed that lower LDL-C levels reduced the risk of blood clots in both groups, but it was more important for patients in the low-risk group, suggesting they should keep their LDL-C levels even lower to prevent thrombosis.
M2 macrophages promote pulmonary endothelial cells regeneration in sepsis-induced acute lung injury.
Ann Transl Med
April 2019
Department of Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai 200032, China.
Background: Macrophages can polarize to M2 phenotype to decrease inflammation and encourage tissue repair. Nonetheless, its role in sepsis-induced acute lung injury and its effect on endothelial cells (ECs) regeneration remains unknown. The aim of the current study was to explore the impact of M2 macrophages on pulmonary ECs proliferation in sepsis-induced acute lung injury.
View Article and Find Full Text PDFEmergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable bla-carrying plasmid by an ST23 strain.
Virulence
December 2018
a State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai , China.
Efficacy and safety of fenofibrate as an add-on in patients with elevated triglyceride despite receiving statin treatment.
Int J Cardiol
October 2016
Department of Cardiology, Jinshan Hospital Fudan University, 1508 Longhang Road, Shanghai 201508, China.
Background: Since the withdrawal of cerivastatin, statin-fibrate combination therapy has been questioned in China due to safety concern. The objective of this study was to evaluate the efficacy and safety profile of fenofibrate as an add-on in patients with dyslipidemia despite receiving statin therapy.
Methods: This was a prospective, multi-center, single-arm, open-label study conducted in Chinese dyslipidemia patients with high CV risk.
Adverse events risk associated with angiogenesis inhibitors addition to therapy in ovarian cancer: a meta-analysis of randomized controlled trials.
Eur Rev Med Pharmacol Sci
June 2016
Department of Intensive Care Unit, Jinshan Hospital Fudan University, Jinshan District, Shanghai, P.R. China.
Objective: Inhibition of angiogenesis has been regarded as an attractive treatment strategy for advanced or recurrent ovarian cancer. We conduct this meta-analysis to investigate the risk of adverse events of special interest related to angiogenesis inhibitors (AIs) in ovarian cancer.
Patients And Methods: Databases from PubMed, Web of Science and Cochrane library up to December 2015 were searched to identify relevant studies.
Factors associated with the effect of open splenectomy for immune thrombocytopenic purpura.
Eur J Haematol
January 2017
Department of Hematology, Zhongshan Hospital Fudan University, Shanghai, China.
Objective: To assess the effect and complications of open splenectomy (OS) for immune thrombocytopenic purpura (ITP) and determine preoperative factors associated with surgical effect.
Methods: This was a retrospective analysis of ITP patients who failed medical therapy and were treated with OS between 1997 and 2014 at the Jinshan Hospital, China. Follow-up was 60 months.