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LncRNA MEG3 inhibits the inflammatory response of ankylosing spondylitis by targeting miR-146a.
Mol Cell Biochem
March 2020
Department of ICU, Jining No.1 People's Hospital (Jining First People's Hospital Affiliated to Jining Medical University), No. 6, Jiankang Road, Jining, 272011, Shandong, China.
Ankylosing spondylitis (AS) is a progressive systemic disease characterized by chronic inflammation response of the sacroiliac joint and spine. Long non-coding RNAs (lncRNAs) are widely involved in the regulation of various diseases. However, the role of lncRNA maternally expressed gene 3 (MEG3) in the inflammatory response of AS has not been studied.
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