Prediction and stratification for the surgical adverse events after minimally invasive esophagectomy: A two-center retrospective study.

Background: Minimally invasive esophagectomy (MIE) is a widely accepted treatment for esophageal cancer, yet it is associated with a significant risk of surgical adverse events (SAEs), which can compromise patient recovery and long-term survival. Accurate preoperative identification of high-risk patients is critical for improving outcomes.

Aim: To establish and validate a risk prediction and stratification model for the risk of SAEs in patients with MIE.

Role of circRMRP and circRPL27 in chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability worldwide, and circRNA dysregulation is functionally associated with COPD. This study explored the potential of circRMRP and circRPL27 as biomarkers of COPD. Blood samples from COPD patients and healthy controls were collected.

GraphkmerDTA: integrating local sequence patterns and topological information for drug-target binding affinity prediction and applications in multi-target anti-Alzheimer's drug discovery.

Identifying drug-target binding affinity (DTA) plays a critical role in early-stage drug discovery. Despite the availability of various existing methods, there are still two limitations. Firstly, sequence-based methods often extract features from fixed length protein sequences, requiring truncation or padding, which can result in information loss or the introduction of unwanted noise.

Therapeutic potential of L. extract on 7,12-dimethylbenz(a)anthracene (DMBA) -induced ovary cancer in Wistar rats: a biochemical, molecular and histopathological approach.

Ovarian cancer (OC) is a significant cause of cancer-related mortality among women. This study explores the efficacy of L. () extract, known for its phytoestrogenic properties, in treating OC through hormonal and metabolic modulation.

A HTO-Type Nonlinear Optical Fluorophosphate with Ultrawide Bandgap.

Compounds having hexagonal tungsten oxides (HTO) topology are of intense research interests owing to their potential functional properties, such as nonlinear optical (NLO) performances. However, most of the reported HTO-type compounds exhibit narrow optical bandgaps because of the d-d electronic transition of compositional d transition metals and lone pair electrons effect of Se/Te, which hinder their applications in the high-energy field, such as deep-ultraviolet (deep-UV) region. In this work, a new fluorophosphate, (NH)[ScF(PO)](POF) exhibiting HTO-topological structures is reported.

Analysis of cardiac developmental toxicity induced by m-cresol in early life of zebrafish and its mechanism.

The compound m-Cresol, also referred to as 3-methylphenol,acts as a precursor in the creation of pesticides and plasticizers. This research has conducted a thorough evaluation of the toxic effects of m-cresol on the cardiac development of juvenile zebrafish, from 6 to 72 hpf. The study's results reveal that higher concentrations of m-Cresol, compared to lower ones, result in more severe heart abnormalities in zebrafish larvae.

Zebrafish as a model system for studying reproductive diseases.

Reproductive system diseases have become a major health challenge facing humans, so extensive investigations are needed to understand their complex pathogenesis and summarize effective treatments. In the study of reproductive diseases, mice are the most commonly used animal model. However, the cost and time required to establish mouse animal models are high.

Effect of Electroacupuncture Treatment on Bladder Function and Urodynamic Features of Neurogenic Bladder in Stroke: A Retrospective Study.

Background: Neurogenic bladder dysfunction is a common consequence of stroke, and it substantially impacts the quality of life and functional independence of affected individuals. Traditional treatment modalities have limitations in achieving optimal outcomes. This study aims to explore the effects of electroacupuncture treatment on bladder function and neurogenic bladder urodynamic characteristics in stroke patients.

Expression and correlation of the long noncoding RNA PDIA3P and FAK/TGF-β pathway in oral submucous fibrosis rats.

Unlabelled: Oral Submucous Fibrosis constitutes a severe condition affecting the lining of the mouth, which carries a risk of developing into oral squamous cell carcinoma, and seriously threaten individuals' lives. Currently, no specific treatment has been utilized to prevent OSF. The detailed mechanism of OSF is still elusive, and this study aims to clarify the mechanism of OSF.

Enhanced removal of sulfonamide antibiotics in water using high-performance S-nZVI/BC derived from rice straw.

Sulfonamide antibiotics (SAs) are widely used in the biomedical field but pose an environmental risk as ecotoxic pollutants. Developing eco-friendly methods to degrade SAs into harmless compounds is crucial. In this work, biochar (BC) was prepared from rice straw via pyrolysis and used to support S-nZVI, thereby forming the S-nZVI/BC composites.

Learning environment as a predictor for medical students' empathy: a multicenter cross-sectional study from 12 medical schools in China.

Background: Empathy of medical students is crucial, yet it tends to decline as students enter later academic years. Empathy appeared to be affected by the learning environment (LE), which could be a potential contributor. We conducted a cross-sectional study to investigate the association between LE and empathy.

Association Between Cognitive Frailty and Depression: A Prospective Cohort Study of Adults Aged 45 Years and Older in China.

Background: The interplay between cognitive frailty and depression remains inadequately understood, with a paucity of evidence from prospective cohort studies. Our study aims to elucidate the relationship between cognitive frailty and the risk of incident depression.

Methods: Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS) spanning 2011, 2013, and 2015, subjects were classified according to cognitive frailty criteria established by an international consensus panel.

A new genus, gen. nov., with two new species and the first description of the female of Long & Yu, 2022 (Arachnida, Araneae, Philodromidae) from China.

Three species of the spider family Philodromidae are reported from the south of China. A new genus, , is described from Jiangxi, Fujian, and Hunan Provinces. It can be distinguished from other genera of Philodromidae by the tegular apophysis of the palp and the cymbial process, as well as by its uniquely striped abdomen.

New insight of electrogenerated HO into oxychlorides inhibition and decontamination promotion: From radical to nonradical pathway during anodic oxidation of high Cl-laden wastewater process.

Anodic oxidation (AO) has been extensively hailed as a robust and promising technology for pollutant degradation, but the parasitic formation of oxychlorides (ClO) would induce a seriously over-evaluated electrochemical COD removal performance and dramatical biotoxicity increasement of the AO-treated Cl-laden effluents. Herein, we shed new light on the roles of HO high-efficiently electrogenerated in three-dimensional (3D) reactor in inhibiting ClO production and promoting pollutant degradation, which has been overlooked in previous literature. Total yield of ClO in phenol simulated wastewater containing 30 mM Cl was dropped from 25 mM and 24.

Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos.

Dipropyl phthalate (DPRP), a plasticizer commonly utilized in the plastics industry, has been identified in food and the environment and has the potential to present a hazard to human health and the environment. In this study, the first comprehensive evaluation of DPRP-induced craniofacial chondrogenic defects was conducted using a zebrafish model. Zebrafish embryos were exposed to 1, 2, and 4 mg/L DPRP from 6 to 96 h post-fertilization.

Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae.

With the widespread application of pesticides, water pollution problems are becoming more and more serious, which is very likely to cause harm to fish. Lower vertebrates, including fish, have the ability to repair damaged tissues. The spread of pesticides in the water may affect their regeneration process after injury, leading to their death, thereby affecting the survival rate of the population.

Unveiling the critical role of surface adsorbed oxygen species for efficiently photothermocatalytic oxidation of VOCs: Replenishing the active surface lattice oxygen sites.

Surface oxygen species play a crucial role in the photothermocatalytic oxidation of volatile organic compounds (VOCs), but their exact functions and evolutionary processes remain unclear. Herein, a series of spinel CoMnO catalysts are synthesized and employed for photothermocatalytic oxidation of toluene. CoMnO catalysts achieve 91.

Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999-2020.

Background: Previous studies have established a correlation between elevated levels of remnant cholesterol (RC) and the occurrence of type 2 diabetes mellitus (T2D) as well as insulin resistance (IR); however, the precise nature of these associations remains incompletely elucidated. This study aimed to evaluate the relationships between RC and IR, as well as RC and T2D, and to determine the extent to which IR mediated the relationship between RC and T2D.

Methods: This was an observational study that utilized cross-sectional methods to examine the general population in the National Health and Nutrition Examination Survey (NHANES) 1999-2020.

The triglyceride-glucose index and risk of cognitive impairment: a systematic review and meta-analysis with inclusion of two national databases.

Background: To investigate the relationship between the triglyceride and glucose (TyG) index and cognitive impairment (CI).

Methods: Five authoritative databases were systematically searched for potentially relevant studies on 'TyG index' and 'CI' from inception to 27 April 2024. Two representative databases from the United Kingdom and United States were also included.

Exploring the predictors of foreign language anxiety: the roles of language proficiency, language exposure, and cognitive control.

This research delves into unexplored territories of Foreign Language Anxiety (FLA), going beyond the traditional focus on language proficiency. We examined the nuanced roles of language exposure and individual differences in cognitive control abilities in shaping FLA. By engaging 46 English learners in a comprehensive assessment, our analysis uncovered significant yet distinct contributions of these factors to various aspects of FLA.

Prognostic Factors in Postoperative Brain Metastases Derive From Non-small Cell Lung Cancer: A Retrospective Analysis.

Background: Brain metastases are crucial in cancer progression, requiring focused efforts on the screening, early detection, and treatment. However, accurate forecasting the postoperative prognosis of patients with non-small cell lung cancer brain metastasis remains a challenge. This retrospective study aims to discern the factors that influence the prognosis of such patients.

Relationship between serum carotenoids and telomere length in overweight or obese individuals.

Background: Previous researches have demonstrated an association between carotenoids and elongated telomeres. Nonetheless, there is scant scientific evidence examining this relationship in individuals who are overweight or obese, a demographic more predisposed to accelerated aging. This study aims to elucidate the correlation between serum carotenoid concentrations and telomere length within this population group.