Integration of protein interaction and gene co-expression information for identification of melanoma candidate genes.

Cutaneous melanoma is an aggressive form of skin cancer that causes death worldwide. Although much has been learned about the molecular basis of melanoma genesis and progression, there is also increasing appreciation for the continuing discovery of melanoma genes to improve the genetic understanding of this malignancy. In the present study, melanoma candidate genes were identified by analysis of the common network from cancer type-specific RNA-Seq co-expression data and protein-protein interaction profiles.

Modified Technique of Cultured Epithelial Cells Transplantation on Facial Segmental Vitiligo.

Background: Cultured epithelial cells transplantation is a known surgical technique for vitiligo.

Objective: To evaluate the factors influencing efficacy and safety of cultured epithelial cells transplantation in 9-month follow-up.

Methods: Demographic, clinical, and repigmentation outcomes were reviewed for patients with facial segmental vitiligo who had undergone cultured epithelial cells transplantation from November 2013 to July 2015 at the clinic of the Department of Dermatology, Huashan Hospital, China.