115,571 results match your criteria: "Jinan University; Shenzhen[Affiliation]"

Natural Enemies Acquire More Prey Aphids from Hormone-Treated Insect-Attracting Plants.

Plants (Basel)

January 2025

Shandong Key Laboratory for Green Prevention and Control of Agricultural Pests, Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

Exogenous plant hormones regulate the agronomic and physiological performance of plants and thus can influence the abundance of insect groups. We surveyed the arthropods on flowering plants and found that the abundance of natural enemies and in the plots treated with salicylic acid (SA) and indole acetic acid (IAA) was significantly increased compared with those in the clean water (control) plots. Then, we investigated the effects of spraying SA, IAA, and clean water on the population parameters of reared on Our results from the age-stage, two-sex life table analysis revealed a significantly shorter pre-adult duration for aphids reared on SA-treated compared to those reared on the other two treatments.

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Development of Molecularly Imprinted Photonic Crystals Sensor for High-Sensitivity, Rapid Detection of Sulfamethazine in Food Samples.

Polymers (Basel)

January 2025

Shandong Key Laboratory of Healthy Food Resources Exploration and Creation, School of Food Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.

As a veterinary drug, sulfamethazine is frequently used to control animal diseases. In this study, a novel molecularly imprinted photonic crystal sensor for the fast visual detection of sulfamethazine in milk and chicken has been developed. Under optimum preparation conditions, a molecularly imprinted, photonic crystal with an anti-opal structure and a clear bright color was prepared and characterized.

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: Rhamnetin 3--α-rhamnoside (ARR) is a major flavonoid of the herb Franch. & Sav., which has been used for treating liver diseases in China.

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Within the framework of 6G networks, the rapid proliferation of Internet of Things (IoT) devices, coupled with their decentralized and heterogeneous characteristics, presents substantial security challenges. Conventional centralized systems face significant challenges in effectively managing the diverse range of IoT devices, and they are inadequate in addressing the requirements for reduced latency and the efficient processing and analysis of large-scale data. To tackle these challenges, this paper introduces a zero-trust access control framework that integrates blockchain technology with inner-product encryption.

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Developing a new type of circularly polarized luminescent active small organic molecule that combines high fluorescence quantum yield and luminescence dissymmetric factor in both solution and solid state is highly challenging but promising. In this context, we designed and synthesized a unique triarylborane-based [2.2]paracyclophane derivative, , in which an electron-accepting [(2-dimesitylboryl)phenyl]ethynyl group and an electron-donating -diphenylamino group are introduced into two different benzene rings of [2.

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The potential health risks posed by the coexistence of nanoplastics (NPs) and triclosan (TCS) have garnered significant attention. However, the effects and underlying mechanisms of NPs and TCS on key functional proteins at the molecular level remain poorly understood. This study reports the effect of polystyrene nanoplastics (PSNPs) on the binding of TCS to human serum albumin (HSA) using multispectral methods and molecular simulation systems.

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The scorpion Karsch is edible and has been an essential resource in traditional Chinese medicine for treating numerous diseases. In this study, two small peptides from hydrolysates were examined to elucidate their potential against gastric cancer. The small peptides (AK and GK) were identified using the LC-QTOF-MS-based approach.

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Recycling end-of-life wind turbines poses a significant challenge due to the increasing number of turbines going out of use. After many years of operation, turbines lose their functional properties, generating a substantial amount of composite waste that requires efficient and environmentally friendly processing methods. Wind turbine blades, in particular, are a problematic component in the recycling process due to their complex material composition.

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To provide insight into the interface structure in Ti particle-reinforced Mg matrix composites, this study investigates the inherent Mg/Ti interface structure formed during the solidification of supercooled Mg melt on a (0001)Ti substrate using ab initio molecular dynamics (AIMD) simulations and density function theory (DFT) calculation. The resulting interface exhibits an orientation relationship of 0001Mg//0001Ti with a lattice mismatch of approximately 8%. Detailed characterizations reveal the occurrences of 0001Mg plane rotation and vacancy formation to overcome the lattice mismatch at the inherent Mg/Ti interface while allowing Mg atoms to occupy the energetically favorable hollow sites above the Ti atomic layer.

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Carbon fiber reinforced plastics inevitably develop defects such as delamination, inclusions, and impacts during manufacturing and usage, which can adversely affect their performance. Ultrasonic phased array inspection is the most effective method for conducting nondestructive testing to ensure their quality. However, the diversity of defects within carbon fiber reinforced plastics makes it challenging for the current ultrasonic phased array inspection techniques to accurately identify these defects.

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Laser powder bed fusion (LPBF)-fabricated Ni-based alloys with high γ' phase fractions generally suffer from cracking that limits their applications. This study presents SD247, a novel alloy that overcomes the challenge of cracking issues and exhibits superior mechanical properties after heat treatment. Compared to CM247LC, SD247 exhibited a lower cracking tendency due to alloying element modification.

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Characterization of the Activities of Vorinostat Against .

Int J Mol Sci

January 2025

Department of Pathogen Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.

is a globally widespread pathogen of significant veterinary and medical importance, causing abortion or congenital disease in humans and other warm-blooded animals. Nevertheless, the current treatment options are restricted and sometimes result in toxic side effects. Hence, it is essential to discover drugs that demonstrate potent anti- activity.

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Optimization of SARS-CoV-2 M Inhibitors by a Structure-Based Multilevel Virtual Screening Method.

Int J Mol Sci

January 2025

Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.

With the aim of developing novel anti-SARS-CoV-2 drugs to address the ongoing evolution and emergence of drug-resistant strains, the reported SARS-CoV-2 M inhibitor was selected as a lead to find novel, highly potent, and broad-spectrum inhibitors. Using a fragment-based multilevel virtual screening strategy, 15 hit compounds were identified and subsequently synthesized. Among them, (IC = 1.

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ERF56, a member of the APETALA2/ETHYLENE-RESPONSIVE FACTOR (AP2/ERF) transcription factor (TF) family, was reported to be an early nitrate-responsive TF in . But the function of in nitrate signaling remains not entirely clear. This study aimed to investigate the role of in nitrate-dependent plant growth and nitrate signaling.

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Following the COVID-19 pandemic, the prevalence of pulmonary fibrosis has increased significantly, placing patients at higher risk and presenting new therapeutic challenges. Current anti-fibrotic drugs, such as Nintedanib, can slow the decline in lung function, but their severe side effects highlight the urgent need for safer and more targeted alternatives. This study explores the anti-fibrotic potential and underlying mechanisms of an endogenous peptide (P5) derived from fibroblast growth factor 2 (FGF2), developed by our research team.

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As the mobile cassette carrier of the methicillin resistance gene that is transported across staphylococci species, the evolution and origin of Staphylococcal Cassette Chromosome (SCC)-and in particular, the composition of and SCC-have been extensively discussed in the scientific literature; however, information regarding its dissemination across geographical limits and evolution over decades remains limited. In addition, whole-genome sequencing-based macro-analysis was unable to provide sufficiently detailed evolutionary information on SCC. Herein, the cassette chromosome recombinase genes , as essential components of SCC, were employed to explore the evolution of SCC.

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Genomic and Metabolomic Analyses of with Enhanced ε-Poly-l-lysine Production Through Adaptive Laboratory Evolution.

Microorganisms

January 2025

State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China.

ε-poly-l-lysine (ε-PL), a natural food preservative, has garnered widespread attention. It is mainly produced by , but the production by wild-type strains fails to meet the demands of industrialization. To address this issue, adaptive laboratory evolution (ALE) was successfully employed in this study, subjecting CICC 11022 to environmental stresses such as acidic pH and antibiotics (rifampicin, gentamicin, and streptomycin).

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Characterizing the Contaminant-Adhesion of a Dibenzofuran Degrader sp.

Microorganisms

January 2025

Shandong Provincial Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Qingdao 266237, China.

The adhesion between dibenzofuran (DF) and degrading bacteria is the first step of DF biodegradation and affects the efficient degradation of DF. However, their efficient adhesion mechanism at the molecular level remains unclear. Therefore, this study first examined the adhesive behaviors and molecular mechanisms of sp.

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The most economically important trait of the is meat quality. Protein deposition is essential in muscle growth and nutritional quality formation. The effects and potential mechanisms of feed protein sources on crustaceans' muscle protein deposition have not been elucidated.

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Antimicrobial resistant (AMR) () isolated from animals may lead to antibiotic treatment failure and economic losses to farmers. The co-existence of antimicrobial resistant genes (ARGs) in the same isolate presents a major challenge for the prevention and control of infection in multidrug-resistant (MDR) Gram-negative organisms. There have been a lot of studies on the antibiotic resistance of in livestock and poultry, but few of them have focused on clinical pathogens.

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Due to oxidative damage and mitochondrial dysfunction, boar semen cryopreservation remains a significant challenge. This study investigates the effects of pyrroloquinoline quinone (PQQ), a mitochondrial-targeted antioxidant, on the post-thaw boar sperm quality during cryopreservation. Boar semen was diluted in a freezing extender containing different concentrations of PQQ (0, 10, 100, 1000, 10,000 nM).

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Comparing the Structural and Physicochemical Properties of Highland Barley -Glucan from Different Sources: A Focus on Color.

Foods

January 2025

Shandong Key Laboratory of Healthy Food Resources Exploration and Creation, School of Food Sciences and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Daxue Road, Changqing District, Jinan 250353, China.

Herein, -glucan (BG) was extracted from different colored varieties of highland barley (HB, ), defined as BBG, WBG, and LBG depending on the colors of black, white, and blue and their molecular structure and physicochemical properties were investigated through a series of technical methods. The high-performance anion-exchange chromatography (HPAEC) results indicated the extracted BBG, LBG, and WBG mainly comprised glucose regardless of color. The molecular weight (M) of BBG, LBG, and WBG were 55.

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Classification of Strawberry Maturity Stages and Varieties Using Neural Networks Based on Volatile Organic Compounds.

Foods

January 2025

College of Biosystems Engineering and Food Science, Key Laboratory of Agro-Products Postharvest Handling of Ministry of Agriculture and Rural Affairs, Zhejiang University, Hangzhou 310058, China.

Volatile organic compounds (VOCs) are closely associated with the maturity and variety of strawberries. However, the complexity of VOCs hinders their potential application in strawberry classification. This study developed a novel classification workflow using strawberry VOC profiles and machine learning (ML) models for precise fruit classification.

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Background: Ageing results in diminished adaptability, as well as declines in physiological and psychological functions and resilience. The epigenetic clock 'Phenotypic Age' (PhenoAge) represents 'preclinical ageing'. Phenotypic Age Acceleration (PhenoAgeAccel) is defined as the residual from a linear regression model predicting PhenoAge on the basis of chronological age.

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A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation.

J Transl Med

January 2025

State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P. R. China.

Background: The high mortality rate of metastatic colorectal cancer (CRC) is primarily attributed to resistance to chemotherapy, where cancer stem cells (CSCs) play a crucial role. Deubiquitinating enzymes are essential regulators of CSC maintenance, making them potential targets for eliminating CSCs and overcoming chemotherapy resistance. This study aims to identify key deubiquitinating enzymes regulating CSCs and drug resistance of CRC.

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