Lymphoepithelial carcinoma of the oral cavity and pharynx: a SEER population-based cohort study.

Objectives: Lymphoepithelial carcinoma (LEC) of the oral cavity and pharynx is a rare cancer, with poorly understood clinicopathological characteristics and prognosis. Only a few case reports or small case series have been reported, so the characteristics and survival of patients with this disease remains unclear. The present study aimed to describe the clinicopathological characteristics and determine the factors associated with survival of this uncommon cancer.

Survival and risk factors of adenosquamous carcinoma in the oral and maxillofacial region: a population-based study.

Background: The features and prognosis of adenosquamous carcinoma (ASC) in oral and maxillofacial region have not thoroughly investigated, the purpose of this study is to describe clinicopathologic characteristics, treatment, and prognostic factors of this disease.

Methods: The data of 276 patients diagnosed with ASC in oral and maxillofacial region between 1975 and 2016 were collected from the Surveillance, Epidemiology, and End Results (SEER) database. The prognostic factors influencing overall survival (OS) and disease-specific survival (DSS) were identified by the Kaplan-Meier analysis and Cox regression analysis.

The combined application of rat bone marrow mesenchymal stem cells and bioceramic materials in the regeneration of dental pulp-like tissues.

This study aims to observe the effects of the combined application of rat bone marrow mesenchymal stem cells (rBMSCs) and a bioceramic material on pulp-like tissue formation. Rat incisor root fragments without pulp tissues were prepared and filled with a collagen scaffold seeded with rBMSCs, while one side of the root segment was covered by a bioceramic material (iRoot BP). After they were cultured for 12 hours, the root fragments were implanted subcutaneously for 3 months.

The effects of Sema3A overexpression on the proliferation and differentiation of rat gingival mesenchymal stem cells in the LPS-induced inflammatory environment.

Semaphorin3A has been identified as a potent osteoprotective factor that simultaneously inhibits bone resorption and promotes bone formation. The present study demonstrates the effect of the overexpression of Sema3A on the proliferation and differentiation of rat gingival mesenchymal stem cells (GMSCs) in the lipopolysaccharide (LPS)-induced inflammatory environment. rGMSCs were transfected with viral stocks of pLenO-GTP-Sema3A (Lv-Sema3A group) or pLenO-GTP (Lv-NC group), with rGMSCs as a control.

MiR-106a* inhibits oral squamous cell carcinoma progression by directly targeting MeCP2 and suppressing the Wnt/β-Catenin signaling pathway.

MicroRNAs (miRNAs) play critical roles in the tumorigenesis and progression of oral squamous cell carcinoma (OSCC). MiR-106a* functions as a tumor suppressor miRNA in several cancers; however, its role in OSCC has not been elucidated. We investigated the role of miR-106a* in human OSCC and explored its relevant mechanisms.

Cerium promotes bone marrow stromal cells migration and osteogenic differentiation via Smad1/5/8 signaling pathway.

Cerium (Ce), one of the lanthanides (Ln), displays a variety of biochemical and physiological effects. However, the potential effect and mechanism of Ce on bone metabolism are not well understood. In this study, we investigated the putative role of Ce in regulating the migration and osteogenic differentiation of bone marrow stromal cells (BMSCs) and the underlying mechanism.

[Fiber post versus metal screw post for repair of residual crowns and roots: a systematic review].

Purpose: To evaluate the restorative effectiveness of fiber post versus metal screw post through systematical review.

Methods: Randomized controlled trials (RCTs) data from the establishment of the database up to June 2013 were searched from MEDLINE (Ovid), PubMed, The Cochrane Library, Embase, Wanfang Data, VIP, CNKI and CBM using the designed strategy. After data extraction and quality review of the retrieved articles by two independent investigators, the softwares of RevMan 5.